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point decrease » point increase (Expand Search)
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), nn decrease (Expand Search)
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20221
Table_5_Integrative Analysis of LGR5/6 Gene Variants, Gut Microbiota Composition and Osteoporosis Risk in Elderly Population.DOCX
Published 2021“…The rs10920362 CT/TT genotype associated with a decreased relative abundance of Actinobacteria (β = −1.32, P < 0.001), Bifidobacteriaceae (β = −1.70, P < 0.001), and Bifidobacterium (β = −1.70, P < 0.001) compared to the CC genotype.…”
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20222
TRPM7 regulates intracellular Ca<sup>2+</sup> and Mg<sup>2+</sup> concentration of cortical astrocytes.
Published 2015“…However, knockdown of TRPM7 in mouse cortical astrocytes significantly decreases intracellular Mg<sup>2+</sup> by 43.5% ± 9.8% (*, <i>p</i> < 0.05, n = 4). …”
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20223
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20224
Ontogeny of the B- and T-cell response in a primary Zika virus infection of a dengue-naïve individual during the 2016 outbreak in Miami, FL
Published 2017“…We collected blood from a female with a maculopapular rash at day (D) 5 and D7 post onset of symptoms (POS) and we continued weekly blood draws out to D148 POS. …”
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20225
Silencing TRPM7 in Mouse Cortical Astrocytes Impairs Cell Proliferation and Migration via ERK and JNK Signaling Pathways
Published 2015“…Knocking down TRPM7 with specific siRNA impairs the proliferation and migration of astrocytes by 40.2% ± 3.9% and 40.1% ± 11.5%, respectively. Consistently, inhibition of TRPM7 with 2-aminoethoxydiphenyl borate (2-APB) also decreases astrocyte proliferation and migration by 46.1% ± 2.5% and 64.2% ± 2.4%. …”
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20226
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20227
Stem Cell-Derived, microRNA-Carrying Extracellular Vesicles: A Novel Approach to Interfering with Mesangial Cell Collagen Production in a Hyperglycaemic Setting
Published 2016“…This resulted in STAT5 down-regulation and a decrease in miR-21 content, TGFβ expression and matrix protein synthesis within MCs. …”
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20228
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20229
Noise pollution limits metal bioaccumulation and growth rate in a filter feeder, the Pacific oyster <i>Magallana gigas</i>
Published 2018“…This latter conclusion points towards a potential risk in terms of ecosystem productivity.…”
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20230
SHOULD MALE CIRCUMCISION BE PROMOTED IN DEVELOPING COUNTRIES AS MAJOR MEANS OF HIV PREVENTION by Wazhma Hakimi.pdf
Published 2020“…However, male circumcision (MC) has been known as a religious or traditional ritual, it was suggested as a mean for prevention of sexually transmitted infections (STIs) in 1850s. …”
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20231
Synonymous Rare Arginine Codons and tRNA Abundance Affect Protein Production and Quality of TEV Protease Variant
Published 2014“…<div><p>It has been identified that a TEV protease (TEVp) variant, TEVp<sup>5M</sup>, displays improved solubility. …”
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20232
microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration - Fig 6
Published 2016“…After vacuum evaporation of HFIP, aliquoted peptide was re-suspended with DMSO to 5 mM and diluted to 5 μM into the cell culture media; <b>(B)</b> cells were treated with a scrambled miRNA-34a sequence (miRNA-34a-<b>sc</b>; 30 nM;, control, <b>a-d</b>, middle row); or <b>(C)</b> with an LNA-stabilized miRNA-34a (30 nM; miRNA-34a stressed; <b>a-d</b>; bottom row); treatments were for 24 hr before incubation with 5 uM of Aβ42 (made up as in [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.ref033" target="_blank">33</a>]) for another 24 hr before assay; MG cells were subsequently stained using a murine amyloid beta MABN10 (red fluorescence λ<sub>max</sub>~650 nm; anti-Aβ antibody, clone W0-2; Millipore, Bellerica MA), a TREM-2 antibody (M-227): sc-48765 (green fluorescence; λ<sub>max</sub>~510 nm; Santa Cruz, Santa Cruz CA) or DAPI nuclear stain (blue fluorescence; λ<sub>max</sub>~470 nm) as in <b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.g003" target="_blank">Fig 3</a>;</b> arrows indicate Aβ42 uptake into MG cells; note decreased presence of TREM2 in miRNA-34a treated MG cells (bottom row, panel B) and decrease in ingested Aβ42 peptide within C8B4 cells (<b>C</b>; bottom row, panel <b>d</b>). …”
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20233
Changes after 45 minutes in the proportion of LTP, LTD or no plasticity responses observed in L5PyNs population induced by the HFS protocol in the presence of D1R agonist or antago...
Published 2015“…<p>(A and D) Percentages of L5PyNs displaying LTP, LTD or no plasticity in 129/Sv mice and 5-HT<sub>1A</sub>R-KO mice in control conditions. …”
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20234
All-Atom Simulations Reveal the Effect of Membrane Composition on the Signaling of the NKG2A/CD94/HLA‑E Immune Receptor Complex
Published 2024“…Our results reveal significant variations in the behavior of the immune complex structure across five different membrane compositions, which include POPC, POPA, DPPC, and DLPC phospholipids, and a mixed POPC/cholesterol system. …”
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20235
BrdU assay in control siRNA (blue bars) and in PAX6 knockdown (red bars) limbal epithelial cells (LECs) without and after 1µM or 5µM RA incubation for 48 hours.
Published 2025“…Significant p values (<0.05) are highlighted. BrdU assay shows a significantly lower proliferation rate in the PAX6 siRNA knockdown group than in control siRNA group (p < 0.001). 5µM RA treatment significantly decreased proliferation rate in controls (p = 0.025). …”
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20236
Table_5_Bacillus velezensis B105-8, a potential and efficient biocontrol agent in control of maize stalk rot caused by Fusarium graminearum.DOCX
Published 2024“…S-NP activity showed an initial increase with a peak of 20,337 nmol/h/g, followed by a decrease, but activity remained significantly better than control treatment with chemical fungicides. …”
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20237
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20238
Islet2a morphant, but not mutant, larvae have a reduced number of dSMNs.
Published 2018“…(E-G) In live 72 hpf tg(islet1:gfp) larvae, dSMNs appeared normal in number and morphology in homozygous mutant (mut; G) compared to heterozygous (het; F) and homozygous wildtype (wt; E) 72 hpf embryos. (H) Cell counts indicated that the number of dSMN somas was not reduced in mutant (n = 9) compared to wildtype (n = 5) or heterozygous (n = 8) <i>islet2a</i> 72 hpf embryos.…”
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20239
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20240
Comparing Cosine and Sine Functions for Calculating the Magnetic Shielding of <sup>29</sup>Si Nuclei across Siliceous Zeolites
Published 2023“…The models, along with α-quartz, were considered to evaluate the advantages of the effects on both chemical shifts and chemical shift anisotropies, as measured for α-quartz and ZSM-12. The decrease of the O dipole with the Si–O–Si angle is usually interpreted as a variation of the electronic density at the O lone pairs. …”