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point decrease » point increase (Expand Search)
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), nn decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 wt » _ wt (Expand Search), 5 ht (Expand Search), i wt (Expand Search)
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19301
FIGURE 5 from Discovery and Characterization of ZL-2201, a Potent, Highly Selective, and Orally Bioavailable Small-molecule DNA-PK Inhibitor
Published 2023“…<p>Phosphoproteomic screen identifies MCM2 Ser108 phosphorylation decreased by ZL-2201. <b>A,</b> Simple Western showing inhibition of pDNA-PK upon treatment with PRKDC siRNA, 300 nmol/L and 3.5 μmol/L of ZL-2201 ± 10 μmol/L bleomycin used in phospho-MS screen analysis. …”
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19302
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19303
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19304
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19305
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19306
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19307
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19308
A representative case of a 68-year-old man with local tumor progression.
Published 2019“…<p>A 68-year-old man (body weight, 70.4 kg; BMI, 24.1 kg/m<sup>2</sup>) underwent multiphasic hepatic CT with dual source DECT at half reduced contrast medium dose. …”
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19309
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19310
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19311
BAG5 inhibited PINK1 degradation.
Published 2014“…<p><b>A:</b> HEK-293 cells were transfected with EGFP-N3, EGFP-BAG5, negative control siRNA (NC) or BAG5 siRNA for 24 h or 48 h. …”
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19312
Table1_Diacerein reduces inflammasome activation and SARS-CoV-2 virus replication: a proof-of-concept translational study.xlsx
Published 2024“…Diacerein has emerged as a potential therapy for COVID-19 due to its potential impact in decreasing the inflammasome activation and coronavirus replication. …”
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19313
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19314
Data_Sheet_5_Construction and Analysis of a ceRNA Network in Cardiac Fibroblast During Fibrosis Based on in vivo and in vitro Data.PDF
Published 2021“…Finally, two mRNA [ADAM metallopeptidase domain 19, (ADAM19) and transforming growth factor beta induced, (TGFBI)], three microRNA (miR-9-5p, miR-124-3p, and miR-153-3p) and two lncRNA (LINC00511 and SNHG15) constituted our ceRNA network. siRNA against LINC00511 increased miR-124-3p and miR-9-5p expression, and decreased ADAM19 and TGFBI expression, whereas siRNA against SNHG15 increased miR-153-3p and decreased ADAM19 expression. …”
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19315
Model parameters.
Published 2024“…If the mask-wearing rate increases from 0% to 50%, the infection risk of norovirus would be decreased by 48.0% (95% CI, 43.5–52.3%). Furthermore, using antimicrobial copper/copper-nickel alloy coatings for most public surfaces could reduce the infection risk by 15.9%-99.2%.…”
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19316
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19317
table1_Health-Related Quality of Life Based on EQ-5D Utility Score in Patients With Tuberculosis: A Systematic Review.pdf
Published 2021“…</p><p>Conclusion: This study showed that the HRQOL based on the EQ-5D utility score of TB patients has significantly decreased, and the TB treatment has a significantly positive effect on the quality of life of patients.…”
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19318
Semaglutide ameliorates cardiac remodeling in male mice by optimizing energy substrate utilization through the Creb5/NR4a1 axis
Published 2024“…The disorders of mitochondrial function and myocardial glucolipid metabolism were significantly ameliorated after NR4a1 knockdown. Overall, Sema ameliorates myocardial glucose, lipid, and energy metabolism disorders by regulating Creb5/NR4a1, thereby protecting against pathological myocardial remodeling. …”
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19319
CXCR3 Antagonism of SDF-1(5-67) Restores Trabecular Function and Prevents Retinal Neurodegeneration in a Rat Model of Ocular Hypertension
Published 2012“…Here we show that the chemokine CXCL12, its truncated form SDF-1(5-67), and the receptors CXCR4 and CXCR3 are expressed in human glaucomatous trabecular tissue and a human trabecular cell line. …”
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19320