Diagnosis of Morquio Syndrome in Dried Blood Spots Based on a New MRM-MS Assay by Claudia Cozma (766350)

“…<div><p>Background</p><p>Mucopolysaccharidosis IVA (MPS IVA; Morquio A disease) is an autosomal recessive disease caused and characterized by a decreased activity of N-acetylgalactosamine-6-sulfate sulfatase (GALNS), resulting in accumulation of keratan sulfate and chondroitin-6-sulfate in tissues and secondary organ damage. …”

Table 1_Preventive beneficial effects of cannabidiol in a reserpine-induced progressive model of parkinsonism.docx by Alvaro C. Lima (11601898)

“…The pathophysiology of PD involves a gradual decrease in dopaminergic neurons in the substantia nigra, increased inflammatory parameters, and augmented oxidative stress in this region. …”

Demonstration of robustness and tunability of our text-based hedonometer, and reasoning for choice of a specific metric. by Peter Sheridan Dodds (188891)

“…Lastly, in plot <b>F</b> (which uses plot <b>A</b>'s legend), we show how coverage of words decreases with word rank. …”

Comparative Proteomic Profiling of 3T3-L1 Adipocyte Differentiation Using SILAC Quantification by Sunkyu Choi (2141545)

“…A search for Chromosome-Centric Human Proteome Project (C-HPP) using neXtprot highlighted one protein with a protein existence uncertain (PE5) and 17 proteins as functionally uncharacterized protein existence 1 (uPE1). …”

Cilostazol inhibits endothelin-induced cytosolic calcium increase and vasoconstiction in mouse femoral arteries. a. by Yoshifumi Kawanabe (308848)

Base-case cost-effectiveness analysis with deterministic sensitivity analysis from a societal perspective. by May Ee Png (627594)

“…</p><p>* Baseline+workdays lost at 0.5 days.</p>†<p> Baseline+workdays lost at 3 days.…”

Telomestatin induces a de-localization of Topo III from TIN2 and TRF1. by Nassima Temime-Smaali (260017)

“…<p>Representative images are of untreated MRC5-V1/YFP-Topo III cells or cells treated for 48 h with 2 µM telomestatin. …”

Comparison of human PRMT7-mediated methylation of human and Xenopus H2B (23–37) peptide substrates over time. by Timothy J. Bondoc (15810634)

Significantly associated SNPs with dEBV for height at withers using a mixed-model approach. by Heidi Signer-Hasler (164244)

“…(additive or allelic) test for association between SNP and trait; the Bonferroni-corrected threshold for a 5% genome-wide significance level is p_BONF = 1.31×10⁻⁶.…”

eLORETA wire diagram illustrating significantly increased functional connectivity (<i>lagged</i> phase synchronization) in the beta2 frequency band in right frontotemporal circuits... by Leonides Canuet (305945)

Funnel plot with nonparametric trim-and-fill analysis for maxillary first (a) and second (b) molar. by Seyed Mohsen Hasheminia (21702533)

Image_1_Risk Factors of Silicosis Progression: A Retrospective Cohort Study in China.TIF by Hua Quan (12339904)

“…Forced vital capacity decreased after 1-year (241.5 vs. 55.2 mL) and 2-year (328.1 vs. 68.8 mL) follow-up in the two groups (AS vs. non-AS). …”

Table_1_Cell-Free DNA as a Diagnostic and Prognostic Biomarker in Dogs With Tumors.XLSX by Jihu Kim (11439451)

“…Dogs with neoplasia and a plasma cfDNA concentration above 1,247.5 μg/L had shorter survival rates than those with levels below this threshold (26.5 vs. 86.1%, respectively, P < 0.05). …”

Table_1_Risk Factors of Silicosis Progression: A Retrospective Cohort Study in China.docx by Hua Quan (12339904)

“…Forced vital capacity decreased after 1-year (241.5 vs. 55.2 mL) and 2-year (328.1 vs. 68.8 mL) follow-up in the two groups (AS vs. non-AS). …”

Use of a Novel Chagas Urine Nanoparticle Test (Chunap) for Diagnosis of Congenital Chagas Disease by Yagahira E. Castro-Sesquen (284439)

“…The nanoparticles concentrate <i>T. cruzi</i> antigens by 100 fold (western blot detection limit decreased from 50 ng/ml to 0.5 ng/ml). The sensitivity of Chunap in a single specimen at one month of age was 91.3% (21/23, 95% CI: 71.92%–98.68%), comparable to PCR in two specimens at 0 and 1 month (91.3%) and significantly higher than microscopy in two specimens (34.8%, 95% CI: 16.42%–57.26%). …”

Solution Properties and Practical Limits of Concentrated Electrolytes for Nonaqueous Redox Flow Batteries by Jingjing Zhang (163589)

“…In this study, we show that ion diffusivities and conductivities of ROM-containing electrolytes reach maxima around 0.5 M and decrease significantly at higher concentrations; realistic limits are established for variations of these parameters. …”

Chronic treatment of non-small-cell lung cancer cells with gefitinib leads to an epigenetic loss of epithelial properties associated with reductions in microRNA-155 and -200c by Michiko Narita (124347)

“…</p><p>Methods and results</p><p>To establish gefitinib-resistant NSCLC cells, gefitinib-sensitive HCC827 cells, which exhibit an in-frame deletion [E746-A750] in EGFR exon 19, were exposed to gefitinib for at least 1.5 months. …”

Effect of Paricalcitol vs Calcitriol on Hemoglobin Levels in Chronic Kidney Disease Patients: A Randomized Trial by Eleonora Riccio (451487)

“…Subjects in Paricalcitol experienced a significant monthly increase of Hb levels equal to +0.16 g/dL [95% C.I. 0.10 to +0.22, p<0.001) while in Group Calcitriol, Hb decrease throughout the follow-up with an average monthly rate of -0.10 g/dL (95% C.I.: -0.17 to -0.04, p<0.001). …”

A 10-Year Analysis of the Effects of Media Coverage of Regulatory Warnings on Antidepressant Use in The Netherlands and UK by Juan Francisco Hernandez (135605)

“…A small decrease of −0.6 DDDs/month (−1.2; −0.05) was observed in Dutch SSRI use shortly after 2003–2004. …”

Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism by Tzu-Yin Lee (4518055)

“…<i>atg5</i>^−/− platelets also exhibited a lower aggregation in response to agonists, and platelet-specific <i>atg5</i>^−/− mice exhibited delayed thrombus formation in mesenteric microvessles and decreased mortality rate due to pulmonary thrombosis. …”