<i>In vivo</i> mitochondrial metabolism in SOD1^−/− mice. by Michael P. Siegel (195229)

“…Data are expressed as means ± SEM with n = 4–5 per group. In C, data are normalized to control averages. …”

Impact of Age on the Cerebrovascular Proteomes of Wild-Type and Tg-SwDI Mice by James L. Searcy (225690)

“…Over 650 proteins were quantified in vessel-enriched fractions from the brains of 3 and 9 month-old wild-type (WT) and Tg-SwDI mice. Sixty-five proteins were significantly increased in older WT animals and included several basement membrane proteins (nidogen-1, basement membrane-specific heparan sulfate proteoglycan core protein, laminin subunit gamma-1 precursor and collagen alpha-2(IV) chain preproprotein). …”

ChIP-seq findings for <i>Pax6</i> and <i>Spry4</i> that lack RARE enhancers or silencers. by Marie Berenguer (8856509)

“…(A) <i>Pax6</i> has 2 RA-regulated peaks (red bars) for H3K27ac (decreased) when RA is lost in E8.5 trunk tissue from <i>Aldh1a2</i>-/- (KO) compared with WT; these RA-regulated peaks do not contain RAREs, suggesting that transcription of <i>Pax6</i> is indirectly activated by RA. …”

Table_1_Clinical and Functional Genetic Characterization of the Role of Cardiac Calcium Channel Variants in the Early Repolarization Syndrome.XLSX by Xiu Chen (1880425)

“…</p><p>Results: Among 104 ERS probands, 16 carried pathogenic variants in calcium-channel genes (32.2 ± 14.6 years old, 87.5% male). The symptoms at diagnosis included syncope (56.3%), ventricular tachycardia/fibrillation (62.5%), and SCD (56.3%). …”

Mossy fiber synaptic LTP - induced by place field specific spiking activity of dentate gyrus granule cells - is presynaptically expressed. by Anja Gundlfinger (366062)

“…Potentiation to ∼220% of control values was visible 30 min after spike train. Data was binned to 0.5 min time points and depicts mean ± sem. (<b>C</b>) CV² analysis of data from experiments in A. …”

Rae1 regulates proliferation in <i>Drosophila</i> and in mammalian cells. by Maryam Jahanshahi (474646)

“…(F) Quantification of pHH3 staining in wing discs undergoing <i>Rae1</i> reduction through heterozygosity at the <i>Rae1</i> locus (<i>c5gal4</i>, <i>Rae1</i>^<i>ex28</i><i>/+</i>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1006198#pgen.1006198.s005" target="_blank">S5K Fig</a>), <i>Rae1</i> RNAi in the whole wing disc (<i>c5>Rae1</i>^<i>IRV</i>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1006198#pgen.1006198.s005" target="_blank">S5L Fig</a>) or both (<i>c5>Rae1</i>^<i>IRV</i>, <i>Rae1</i>^<i>ex28</i><i>/+</i>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1006198#pgen.1006198.s005" target="_blank">S5M Fig</a>) show an increase in pHH3 positive cells relative to control wing discs (<i>c5gal4/+</i>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1006198#pgen.1006198.s005" target="_blank">S5J Fig</a>). …”

<i>C. elegans</i> EGL-4 regulates quinine sensitivity in ASH. by Michelle C. Krzyzanowski (433112)

“…<p>(A) <i>egl-4(lof)</i> animals respond better than wild-type animals to dilute (1 mM) quinine, while <i>egl-4(gof)</i> animals show a decreased sensitivity to 10 mM quinine, when compared to wild-type animals. p<0.0001 for each. …”

Average internal state of the colony for various colony sizes (<i>N</i> = 20–200 at increments of 20 workers). by Simeon Adejumo (14838827)

“…At smaller colony sizes (<i>N</i> = 20, 40, and 60), the average internal state of workers decreases as a function of time and stabilises at a point which is lower than the initial value. …”

Perifosine targets the Aldefluor-positive cell population in breast cancer xenografts. by Hasan Korkaya (159560)

“…Scale bars = 100 µm. Data represent the mean±SD of experiments with five mice in each group.…”

Pharmacokinetics and pharmacodynamics after treatment of DIO-mice with HI, X10 and IGF-1 by sc injection. by Henning Hvid (486358)

“…Dotted line indicates mean blood glucose at time 0. Error bars; SEM. C: Plasma concentrations 0.5 h and >5 h after treatment with HI or X10, 600 nmol/kg. …”

Comparison of Invasive Blood Pressure Measurements from the Caudal Ventral Artery and the Femoral Artery in Male Adult SD and Wistar Rats by Ying Wang (11406)

“…</p> <p>Results</p><p>There was a significant difference in the rate of distal ischemia between femoral and caudal ventral arteries after catheterization (25% <i>vs</i> 5%, <i>P</i><0.05). The overall mean gradient and the mean gradient under a steady hemodynamic state were 4.9±3.7 mm Hg and 5.5±2.5 mm Hg, respectively. …”

Lysosomal degradation is impaired in cystinosis cells. by Ekaterina A. Ivanova (713261)

“…<p>(a) Trafficking and degradation of endocytic cargo was evaluated by means of fluorescently labelled Alexa-555-BSA and fluorogenic substrate DQ-BSA: control and cystinotic ciPTEC cells were incubated with 5 μg/ml of each substrate for 2 h, washed and analyzed under confocal microscope (live imaging). …”

Effect of palladin depletion on terminal differentiation of C2C12 cells. by Ngoc-Uyen-Nhi Nguyen (723223)

“…<b>(C)</b> Fusion index analysis of stable transfectants at day 5 (left) and day 7 (right) of differentiation. …”

Blue fluorescent cGMP sensor Cygnus. by Yusuke Niino (253286)

“…Half-maximal effective concentration (EC₅₀) values for cGMP and cAMP were 1.0±0.2 µM and 0.4±0.3 mM (means ± s.e.m., <i>n</i> = 4), respectively. (D) Comparative measurements of cGMP dynamics in PC12 cells expressing cGES-DE5 and Cygnus. …”

Immunohistochemical staining for LAMP-1 (CD107a) of CT26.CL25 tumors. by Pawel Mroz (156435)

“…CT26.CL25 PDT treated tumors day 5. D. CT26.CL25 non-treated, contralateral tumors day 5. …”

Endogenous ROS modulate the nitrite-induced hypoxic vasodilation response. by Matthias Totzeck (620367)

“…Incubation of SOD mimic tempol with catalase and with catalase/ebselen significantly increased the vasodilation response at 10 and 15 min (*<i>P</i><0.05, n = 3–5). Values are means±s.e.m.</p>…”

Figure 4, supplementary figure 6 by Kristen Pleil (11084931)

“…</b>a) Systemic E2 synthesis inhibition in high ovarian E2 mice using the aromatase inhibitor letrozole (LET, 10 mg/kg). b) Effects of LET administration on EtOH consumption (N’s = 13 saline VEH, 19 LET). c) Effects of LET administration on elevated plus maze (EPM) % time spent in the open arms (left) or distance traveled (right; N’s = 15 VEH, 14 LET). d) Intra-BNST infusion of LET (1 μg in 200 nl/side) in high E2 status females. e) Effects of intra-BNST LET on EtOH consumption (N’s = 7 VEH, 6 LET). f) Intra-BNST infusion of E2 (20 pg in 200 nl/side) or membrane-impermeable E2 (mE2, 55 pg in 200 nl/side) in low E2 status females. g) Effects of intra-BNST E2 on EtOH consumption (N’s = 8 VEH, 7 E2). h) Effects of intra-BNST mE2 on EtOH consumption (N’s = 12 VEH, 11 mE2). i) Effects of intra-BNST E2 on EPM % time spent in the open arms (left) or distance traveled (right; N’s = 7 VEH, 8 E2). j) Effects of bath application of E2/mE2 on excitatory synaptic transmission in BNSTCRF neurons during slice electrophysiology recordings in low ovarian E2 status female CRF-CrexAi9 reporters. k) Spontaneous excitatory postsynaptic currents (sEPSCs) maximum delta from % baseline during E2/mE2 wash on (E2 nM: 0.01: N = 2, 2 cells; 1: N = 4, 4 cells; 10: N = 5, 7 cells; 100: N = 4, 4 cells; 1000: N = 3, 5 cells; 100 nM mE2: N = 3, 6 cells; l and m are the same cells). l) Time course of BNSTCRF neurons that displayed increase/decrease/no change in sEPSC frequency and amplitude (m) % change from baseline during E2 application and proportion of responding categories (pie charts). …”

NK cell depletion following DC expansion interferes with the regulation of decidual angiogenesis. by Irene Tirado González (130195)

“…DC expansion led to a significant decrease in sFlt-1 concentrations from gd 5.5 to gd 7.5. …”

Summary of 2D-GE Differential Protein Spots. by Stephanie M. Cologna (125652)

“…In week one, 22 were unique to this time point whereas 8 were unique to week three and 37 were unique to week five. …”

Carotenoids, sugars, ascorbic acid, total phenolics, and antioxidant activity of murici from Brazilian Cerrado during refrigerated storage by Celso Martins Belisário (8651982)