Pharmacodynamic effects of dasatinib on the Src pathway. by Aaron J. Scott (4412410)

“…<p>A) Treatment with dasatinib (0.8 μmol/L) at 0.5h, 1h, 2h, 4h, and 8h significantly reduced the activation of Src, FAK and paxillin at all time points examined in the HCT116 sensitive CRC cell line when compared to control. …”

Phase diagrams in the Δ<i>c</i>/<i>c</i>—Δ<i>ζ</i>/<i>ζ</i> plane for different shock lengths. by Dhruv Sharma (10219121)

“…<i>Middle Row</i>: Shock lasts for 6 months. A decrease in the region of no-crisis is observed. …”

HS-dependent infectivity of the CHIKV E2 mutants by removal of HS on MC3T3-E1 cells. by Christina L. Gardner (369959)

“…For all of the CHIKV E2 mutants, with the exception of LR-159R at 0.5 U/mL of Hep III, had a significant decrease in infectivity compared to the mock-treated control (<i>p<0.01</i>).…”

Volcano plot of protein abundance changes during peak infection at MOI = 1. by Jacque C. Young (161065)

“…Red color indicates an increase in abundance, green a decrease in abundance, and grey, no change. Diamonds represent host proteins: 1.) glyceraldehyde -3-phosphate dehydrogenase, 2.) pyruvate kinase, 3.) 3-phosphoglycerate kinase, 4.) ribosomal protein S9, 5.) ribosomal protein S8, 6.) …”

Data_Sheet_4_Flavonoid Derivative of Cannabis Demonstrates Therapeutic Potential in Preclinical Models of Metastatic Pancreatic Cancer.pdf by Michele Moreau (5726120)

“…<p>Pancreatic cancer is particularly refractory to modern therapies, with a 5-year survival rate for patients at a dismal 8%. …”

Image 2_Spatial deciphering of the transcriptomic heterogeneity of tumor spread through air spaces in lung cancer.tif by Wenhao Wang (515852)

“…Meanwhile, an increase in CD4 T memory cells and a decrease in B cells were observed in the tumor immune microenvironment of STAS. …”

Image 4_Spatial deciphering of the transcriptomic heterogeneity of tumor spread through air spaces in lung cancer.tif by Wenhao Wang (515852)

“…Meanwhile, an increase in CD4 T memory cells and a decrease in B cells were observed in the tumor immune microenvironment of STAS. …”

The half-life of Cln2 is not reduced in <i>rts1</i>Δ cells. by Karen Artiles (257262)

“…<p>(A) Inactivation of the SCF E3 ubiquitin ligase does not cause increased Cln2 protein levels in <i>rts1</i>Δ cells. …”

Effect of Particle Shape on Capillary Forces Acting on Particles at the Air–Water Interface by Nirmalya Chatterjee (171737)

“…The particles (5 mm nominal size) were made of polyacrylate and were fabricated using a 3D printer. …”

The cephalic lateral line system of temperate perches (Perciformes: Percichthyidae) from Argentinean Patagonia by Rocío M. Vega (12844196)

“…Specimens were bleached in 5% H2O2 and the canal systems of their cephalic lateral line were filled with hematoxylin. …”

Molecular Tectonics. Disruption of Self-Association in Melts Derived from Hydrogen-Bonded Solids by Danielle Boils (2707627)

“…In tectons <b>3</b>−<b>5</b>, for example, simple triaminotriazine groups grafted to a nominally tetrahedral tetraphenylmethyl core form intermolecular hydrogen bonds according to reliable motifs, and crystallization thereby leads to the formation of porous three-dimensional networks. …”

Droplet Microfluidic System with On-Demand Trapping and Releasing of Droplet for Drug Screening Applications by Matthew Courtney (3396641)

“…This work demonstrates a droplet microfluidic platform that has the potential to significantly reduce the reagent consumption and shorten the reaction and analysis time by utilizing nanoliter-sized droplets as a replacement of wells. …”

raw data of "Helicobacter hepaticus promotes hepatic steatosis through CdtB-induced mitochondrial stress and lipid metabolism reprogramming" by Quan Zhang (20376574)

“…Furthermore, we identify that CdtB translocates to mitochondria with the assistance of Hsp90, leading to a decrease in the activity of mitochondrial respiratory complex V due to its interaction with ATP5A1. …”

Data_Sheet_3_Flavonoid Derivative of Cannabis Demonstrates Therapeutic Potential in Preclinical Models of Metastatic Pancreatic Cancer.pdf by Michele Moreau (5726120)

“…<p>Pancreatic cancer is particularly refractory to modern therapies, with a 5-year survival rate for patients at a dismal 8%. …”

Predicted Functional RNAs within Coding Regions Constrain Evolutionary Rates of Yeast Proteins by Charles D. Warden (85098)

“…We then analyzed the impact of coding fRNAs on the evolutionary rate of protein-coding genes because a decrease in evolutionary rate implies constraint due to biological functionality. …”

Data Sheet 1_Spatial deciphering of the transcriptomic heterogeneity of tumor spread through air spaces in lung cancer.zip by Wenhao Wang (515852)

“…Meanwhile, an increase in CD4 T memory cells and a decrease in B cells were observed in the tumor immune microenvironment of STAS. …”

Deletion of Dclk1 exacerbates colonic barrier dysfunction following DSS treatment. by Dongfeng Qu (455807)

“…Western blot analysis of tight junction and adherens junction proteins demonstrated a decrease in Claudin-1, Claudin-7, and E-cadherin in the Villin^Cre;Dclk1^f/f mice after DSS treatment; <b>D.…”

Cryopreservation Causes Genetic and Epigenetic Changes in Zebrafish Genital Ridges by Marta F. Riesco (425309)

“…Our results indicated that cryopreservation produced a decrease in most of the zebrafish studied transcripts (<i>cxcr4b, pou5f1, vasa</i> and <i>sox2</i>) and upregulation of heat shock proteins (<i>hsp70, hsp90</i>). …”

Figure 7 by Ana Carmena (274350)

“…</p> <p>Lane 4, 5 and 6: The addition of increasing amounts of Dsh leads to a decrease in the amount of *Ras^V12 co-IP with Cno.…”

Chromosome Segregation Analysis in Human Embryos Obtained from Couples Involving Male Carriers of Reciprocal or Robertsonian Translocation by Ahmet Yilmaz (132195)

“…Involvement of non-acrocentric chromosome(s) or terminal breakpoint(s) in reciprocal translocations was associated with an increase in the percent of embryos consistent with adjacent 1 but with a decrease in 3∶1 segregation. Similar results were obtained in the analysis of nontransferred embryos donated for research. 3∶1 segregation was the most frequent segregation type in both day 3 (31%) and spare (35%) embryos obtained from carriers of t(11;22)(q23;q11), the only non-random REC with the same breakpoint reported in a large number of unrelated families mainly identified by the birth of a child with derivative chromosome 22. …”