Splicing assays of wt and mutant pre-mRNA in the absence and presence of wild-type StpA and mutant G126V-StpA by Rupert Grossberger (9105)

“…The reactions were performed in the presence of 5 mM MgCl, 0.5 mM GTP, 50 mM Tris–HCl (pH 7.3) and 0.4 mM spermidine (see Materials and Methods). () Splicing of the wt intron pre-RNA without added protein (full circles), with the addition of 1.4 μM wild-type StpA (full squares) or 1.4 μM G126V-StpA mutant (empty squares). () Splicing of the C865U pre-RNA intron mutant without protein (full circles), with addition of 1.4 μM wild-type StpA (full squares) or 1.4 μM G126V-StpA mutant (empty squares). …”

Expression of a 65kDa isoform of eIF2Bε leads to a global decrease in protein synthesis. by Lauren K. Brady (4479244)

Blocking C5L2 decreased C5a-primed neutrophils for ANCA-induced respiratory burst. by Jian Hao (160736)

RhoE gt/gt mice show a delay in neuromuscular junction maturation and a decrease in the number of spinal motoneurons. by Enric Mocholí (223047)

IC₅₀ values of REJO SP mutants vs. WT by MAbs targeting V2i, V3, V2q, and the CD4bs and by CD-IgG2. by Chitra Upadhyay (817121)

Histological findings of adult WT and <i>Gli1</i>^+/− mice. by Yoshiaki Kitaura (644233)

PM exposure affects small airways to a greater degree in WT compared to Ager^-/- mice. by Erin J. Caraher (4445902)

“…<p>(A) WT-PM mice had significantly elevated tissue resistance at 1Hz p<0.001 (*). …”

Decreased CCL2 levels protect A20^AEC-KO mice against influenza A infection by Jonathan Maelfait (181048)

Kinetic and equilibrium constants for binding of WT and mutant FVIII-C2 proteins to BO2C11. by Jasper C. Lin (685807)

“…The kinetic range for the Biacore T100 is: k_a constants from ~10³–10⁷ M^-1s^-1; k_d constants from ~10^-5–0.5 s^-1. …”

Inhibition of the EphA4-c-Abl pathway decreases the loss of dendritic spines and apoptosis induced by AβOs. by Lina M. Vargas (540995)

Fli-1 directly activates miR-17-92 promoter and contributes to miR-17 and miR-20a expression in NN10#5 cells. by Samer Kayali (133888)

“…<p>A: NN10#5 cells have been cultured for two days in absence or presence of Dox used to induce Fli-1 knock-down before analysis. …”

Results of XCOM and step velocity. by Saori Miyagishima (14593506)

Subjects:

MDSCs decrease the frequency of Th17 cells in mice with DSS-induced colitis. by Jing Zhang (23775)

“…A) Adoptive transfer of MDSCs decreased serum IL-17 level in DSS-treated WT mice. …”

Summary of five key points guiding the Safe Steps evaluation and implementation. by Esario IV Daguman (21474116)

M^pro confers a significant reduction in growth in yeast caused by decreases in a variety of cellular proteins. by Jin Ou (16914305)

Increase of total proteinuria and decrease of renal function in mice lacking CD73. by Cornelia Blume (321209)

Cdk5 inhibition by olomoucine prevents the fragmentation of the Golgi and decreases Tau secretion. by Nguyen-Vi Mohamed (323606)

Deletion of STX1B decreases the size of RRP in glutamatergic and GABAergic synapses. by Tatsuya Mishima (529071)

“…<p>(A) Average EPSC evoked by application of 0.5 M hypertonic sucrose solution for 15 s in WT and STX1B^−/− neurons (left). …”

Human RBS cells showed severely slow proliferation and decreased protein translation. by Baoshan Xu (158726)

Deficiency in ArgEF but not ArgB decreases extra- and intracellular siderophore production. by Nicola Beckmann (194193)