Schematic of experimental paradigms. by Shiva Farashahi (5018381)

“…Following the appearance of the fixation cross and information about the maximum reward (50 and 100 points), subjects were presented with a diminishing arc informing them about the rate of reward decrease on a given trial. …”

Image_1_The global regulator FpLaeB is required for the regulation of growth, development, and virulence in Fusarium pseudograminearum.tif by Yuxing Wu (3818197)

Preferential down-regulation of miRNAs and overexpression of XY genes in GCKO testis samples by P18. by Anne R. Greenlee (304274)

“…B) Validation of Febit miRNA array fold changes by qRT-PCR and primers amplifying miR-34b-3p, -15b-5p, -19a and -191. In comparison to WT (n  = 3; RFC  = 1.0), significant reductions in GCKO miRNA expression were observed using qRT-PCR and P18 RNA from GCKO testes (n = 3). …”

Targeted deletion of PPARγin macrophages inhibits lung cancer metastasis in an orthotopic mouse model of non-small cell lung cancer. by Howard Li (194066)

“…<p>Following lethal irradiation, WT C57BL/6 mice received bone marrow from either PPARγ-Mac^neg (KO) or PPARγ^flox/flox (Flox) donor mice as described in the “<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0028133#s4" target="_blank">Methods</a>” section. …”

Physiological indices of irrigated rice affected by flooding and nitrogen fertilization by Alberto Baêta dos Santos (8074955)

Classification analysis. by Shayoni Ray (179927)

Detergent-free staining shows all Sdc constructs localize to the synapse. by Margaret U. Nguyen (3177789)

Piroxicam and vehicle control do not impact canine UC cells <i>in vitro</i>. by Jordon M. Inkol (11237604)

“…<p>Representative IC50 curves for piroxicam treatment of AXA, Orig, and SH cells show no dose dependent decrease in cell viability up to 1mM (A). …”

dFmr1 regulates heart rate. by Stefanie Mares Novak (826953)

“…<b>(B)</b> Loss of dFmr1 (<i>dFmr1</i>^<i>3/50M</i>, N = 16) results in a statistically significant decrease in heart rate when compared to wild type (<i>w</i>^<i>1118</i>, N = 10). …”

Uniportal VATS Right Lower Lobectomy and Lymphadenectomy: Step-by-Step by Hussein Elkhayat (4426768)

Table_1_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.XLSX by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_1_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.PDF by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_3_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.PDF by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_2_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.pdf by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_4_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.PDF by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Loss of intestinal epithelial Shh signaling deregulates intestinal crypt epithelial proliferation. by Jessica Gagné-Sansfaçon (571087)

“…Proliferation assays were performed by PCNA immunostaining (G and H, green labeling), with Evans blue serving as counterstain (red staining). Mutants displayed a decrease in cell proliferation as shown by a decrease in the number of PCNA-labeled proliferating cells (H) when compared to controls (G). …”

Test scores and ordering costs. by Jinghong Ma (1755838)

Displacement of site marker ligands bound to HSA in presence of increasing PS concentrations. by Shevin R. Feroz (468333)

“…Spectra marked as ‘a’, ‘b’, ‘c’ and ‘d’ refer to 10 µM BR, 10 µM HSA, 50 µM PS and PS–HSA (5∶1) complex, respectively. …”

Other glycines substitutions that destabilize BH4-Bcl-2’s by Giovanni Monaco (452223)

“…Data points represent means ± SEM. * indicates a statistically significant difference from vehicle control.…”

Nonhistaminergic itch requires Pirt. by Kush N. Patel (350598)

“…(<b>D</b>, <b>E</b>) The 5HT₂-selective agonist α-Me-5HT (30 µg) produces decreased scratching in KO mice (n = 8; WT, n = 13). …”