Compromised angiogenesis and vascular Integrity in impaired diabetic wound healing by Uzoagu A. Okonkwo (8754933)

“…As compared to wild type, vessel surface area, branch junction number, total vessel length, and total branch number were significantly decreased in wounds of diabetic mice as compared to WT mice. …”

Discovery of Novel Substituted <i>N</i>‑(4-Amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide Analogues as Potent Human Adenovirus Inhibitors by Jimin Xu (2208961)

“…Notably, among these derivatives, compound <b>15</b> showed improved anti-HAdV activity (IC₅₀ = 0.27 μM), significantly decreased cytotoxicity (CC₅₀ = 156.8 μM), and low <i>in vivo</i> toxicity (maximum tolerated dose = 150 mg/kg in hamster) as compared with niclosamide, supporting its further <i>in vivo</i> efficacy studies for the treatment of HAdV infections.…”

Pre-incubation of SB105-A10 either with HIV-1_IIIb or HIV-1_ada strains inhibits the viral infectivity in dilution assay. by Isabella Bon (467395)

“…<p>HIV-1 strains were incubated for 1 hour at 37°C with SB105-A10 (20 µg/ml; 4.2 µM). Following this incubation the samples were diluted 50-fold to reduce dendrimer concentrations to a level below that at which SB105-A10 significantly inhibits HIV replication and challenged with activated PBMCs. …”

Comparison of TPH2 expression in the ventral tegmental area and raphe. by Motoki Imai (7324697)

Time course of viral DNA and CP mRNA accumulation in <i>N</i>. <i>benthamiana</i> plants infiltrated with wild type or <i>cle-</i> mutant TGMV or CaLCuV. by Jacqueline Williams (3493745)

Purine Metabolism changes in response to liver irradiation. by Irwin Jack Kurland (749962)

Alpha rhythm cluster. by Eduardo Ekman Schenberg (801650)

“…B) Post-hoc analysis revealed decreases in the cluster depicted at left to be significant after 50 minutes from ingestion of ayahuasca (*p<0.05, corrected). …”

SARS-CoV-2 infected Tryptophan hydroxylase 2 (TPH2)-positive cells in the ventral tegmental area. by Motoki Imai (7324697)

SARS-CoV-2 infected Tryptophan hydroxylase 2 (TPH2)-positive cells in the ventral tegmental area. by Motoki Imai (7324697)

CREB Targets Define the Gene Expression Signature of Malignancies Having Reduced Levels of the Tumor Suppressor Tristetraprolin by Mohammad Fallahi (200679)

“…These analyses defined a signature of 50 genes differentially regulated between high and low <i>TTP</i>-expressing tumors. …”

A. Quality of evidence: TOTVA vs. COT. B. Quality of evidence: TOTVA vs. NTET (including robotic approaches). by Huixia Ren (500186)

Passenger mutations accurately classify human tumors by Marina Salvadores (6589187)

“…In particular, introducing the RMD features into a combined classification model increased the fraction of diagnosed patients by 50 percentage points (at 20% FDR). …”

The Association of Geographic Coordinates with Mortality in People with Lower and Higher Education and with Mortality Inequalities in Spain by Enrique Regidor (636687)

“…</p><p>Methods</p><p>Data are from a nation-wide prospective study covering all persons living in Spain's 50 provinces in 2001. …”

Correlations between the percentage of total sperm motility and GABA A-α1 receptor expression in sperm. by Paweena Kaewman (14329011)

Propofol enables sustained alpha firing in thalamus. by Austin E. Soplata (4676017)

Analysis of <i>gstA2</i> expression in RNAi-<i>gstA2</i> knockdown cells. by Mamatha Garige (10719830)

“…M, molecular weight markers (50–2000 bp); <i>rnla</i> (70 bp). Western blot analysis of these cells with a rabbit anti-DdGSTA2 polyclonal antibody indicated ~80% decrease in GSTA2 protein (D, E).…”

Single simulation illustrating trough-max and the switch to peak-max. by Austin E. Soplata (4676017)

(a, b). The statistical error analyses for the models using the same dataset. by Fahd Saeed Alakbari (10701871)

Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells through Lead Optimization by Yin Yuan (597540)

“…Among them, compound 7c exhibited the best inhibitory activity with an IC₅₀ value of 41.8 nM. Furthermore, it was found that <b>7c</b> decreased the expression of stemness markers, spheroid formation, and metastatic ability as well as tumor-initiation capability in a concentration-dependent manner in vitro and in vivo. …”

Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells through Lead Optimization by Yin Yuan (597540)

“…Among them, compound 7c exhibited the best inhibitory activity with an IC₅₀ value of 41.8 nM. Furthermore, it was found that <b>7c</b> decreased the expression of stemness markers, spheroid formation, and metastatic ability as well as tumor-initiation capability in a concentration-dependent manner in vitro and in vivo. …”