Implementation of a National Reference Laboratory for Buruli Ulcer Disease in Togo by Marcus Beissner (139059)

“…Compared to a previous study, the rate of BUD patients with non-ulcerative lesions increased from 37% to 50%, the mean duration of disease before clinical diagnosis decreased significantly from 182.6 to 82.1 days among patients with ulcerative lesions, and the percentage of category III lesions decreased from 30.3% to 19.2%.…”

Image_1_Cardiac resynchronization therapy in heart failure patients by using left bundle branch pacing.TIF by Ying Gu (203149)

“…</p>Results<p>Left bundle branch pacing was successful in all 34 patients (mean age 65.6 ± 11.2 years, 67.6% men). A significant decrease in QRS duration (QRSd) was observed after the LBBP operation for 1 month (153.2 ± 1.7 vs. 111.9 ± 2.6 ms, p < 0.01). …”

Hunchback directly represses <i>eve3+7</i>. by Ben J. Vincent (5727950)

“…Top: wild-type <i>eve3+7</i> (wt: n = 26; <i>sna</i>::<i>hb</i>: n = 19); Bottom: <i>eve3+7mutHb</i> (wt: n = 9; <i>sna</i>::<i>hb</i>: n = 13). …”

Intracellular LF82 multiplication requires stress responses. by Gaëlle Demarre (249248)

“…Horizontal lines indicate viability decrease by 2, 5 and 10 fold compared to WT LF82. Data were analyzed using a Student’s <i>t</i> test: * <i>P</i> <0.05, ** <i>P</i> <0.01, *** <i>P</i> <0.001, **** <i>P</i> <0.0001 (black stars correspond to mutant vs WT, blue stars correspond to mutant vs its complementation).…”

VACV infection induces non-canonical STAT3 phosphorylation at S727 in a VGF-dependent manner. by Anil Pant (10074299)

“…HFFs were infected with MOI of 5 of WT-VACV with or without 3 μM afatinib treatment. …”

Sacrifice Template Strategy to the Fabrication of a Self-Cleaning Nanofibrous Membrane for Efficient Crude Oil-in-Water Emulsion Separation with High Flux by Mingming Wu (268965)

“…More importantly, the as-prepared MCNM still maintained exceptional underwater superoleophobicity in harsh environment (3.5 wt % NaCl, 4 M HCl, 50 °C hot water) even after ultrasound for 1 h. …”

Merlin loss increases SC NPC growth, glial differentiation and cell survival. by Cynthia Garcia (562261)

“…(<b>G</b>) <i>Nf2 loss</i> results in increased glial (3-fold) (p = 0.0002; two-tailed Mann-Whitney U-test), but decreased neuronal (4.6-fold) (p<0.0001; two-tailed Mann-Whitney U-test) and oligodendrocyte (5-fold) differentiation (p<0.0001; two-tailed Mann-Whitney U-test). …”

Toll-Like Receptor 9 Deficiency Protects Mice against <i>Pseudomonas aeruginosa</i> Lung Infection by Fatima BenMohamed (530333)

“…While a number of studies have demonstrated the roles of TLR2, TLR4 and TLR5 in host defense againt <i>P. aeruginosa</i> infection, the implication of TLR9 in this process has been overlooked. …”

Th17 cells can inhibit <i>T</i>. <i>cruzi</i> intracellular growth in macrophages <i>in vitro</i> by inducing NADPH oxidase via IL-17A. by Catherine W. Cai (3188976)

“…<p>PEMs were infected with trypomastigotes for 3 hours (MOI = 5). <i>T</i>. <i>cruzi</i>-specific TCR Tg Th1 or Th17 cells were then added to macrophages 1:25. …”

Sacrifice Template Strategy to the Fabrication of a Self-Cleaning Nanofibrous Membrane for Efficient Crude Oil-in-Water Emulsion Separation with High Flux by Mingming Wu (268965)

“…More importantly, the as-prepared MCNM still maintained exceptional underwater superoleophobicity in harsh environment (3.5 wt % NaCl, 4 M HCl, 50 °C hot water) even after ultrasound for 1 h. …”

<i>dhs-16</i> mutant animals are deficient in lathosterone. by Joshua Wollam (172952)

“…(D) LC/MS/MS analysis of lipid extracts from L3 stage animals reveals that lathosterone levels are reduced in <i>dhs-16(tm1890)</i> mutant animals compared to N2 wild-type (WT) animals, shown quantitatively in (E). Lathosterone levels are significantly reduced in <i>dhs-16</i> animals relative to N2 wild-type (3.5-fold decrease; <i>N</i> = 7, M ± SD; **<i>p</i><0.001). …”

Sacrifice Template Strategy to the Fabrication of a Self-Cleaning Nanofibrous Membrane for Efficient Crude Oil-in-Water Emulsion Separation with High Flux by Mingming Wu (268965)

“…More importantly, the as-prepared MCNM still maintained exceptional underwater superoleophobicity in harsh environment (3.5 wt % NaCl, 4 M HCl, 50 °C hot water) even after ultrasound for 1 h. …”

Disruption of core-AP2M1 binding abolishes recruitment of AP2M1 to LD and alters the sub-cellular localization of core and its colocalization with E2. by Gregory Neveu (142972)

“…TGN46 (green), demonstrating decreased localization of core to TGN in Huh-7.5 cells electroporated with J6/JFH RNA harboring the Y136A core mutation (right panel) compared with WT core (left panel). …”

RSK2 activates the Atm/p53-dependent DNA damage pathway under genotoxic stress. by Han Chi Lim (439624)

“…RSK2 activates the Atm/p53-dependent DNA damage pathway under genotoxic stress in MEFs. RSK2 WT and KO MEFs were isolated from E14.5 mouse embryos. …”

<i>Slytherin</i> external phenotype, genotype, cloning and mRNA rescue of <i>srn</i> mutants. by Yuanquan Song (238595)

“…In embryos injected with WT <i>gmds-gfp</i> mRNA, the percentage of mutants scored by external phenotypes was significantly decreased, to ca. 5% (<i>gmds-wtL-gfp</i> 5.4±2.5%, 401 embryos, 3 carrier pairs; <i>gmds-wtS-gfp</i> 5.1±0.6%, 587 embryos, 4 carrier pairs; one-way ANOVA, followed by Dunn's pairwise comparison, p<0.05). …”

Effects of the transobturator tape procedure on overactive bladder symptoms and quality of life: a prospective study by Salih Polat (8185269)

“…At the first-year follow-up, 52 patients (50.0%) and 59 patients (56.7%) reported cure in preoperative urgency and urgency incontinence, respectively. …”

Effect of rapamycin/FK506 pharmacology on caste characters in honey bees (Vehicle = 2% ethanol in insect saline; FK+R = sequential treatment of FK506, rapamycin; R = rapamycin; W =... by Avani Patel (30611)

“…Corbicula is associated with low basitarsus length/width ratio <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0000509#pone.0000509-Dedej1" target="_blank">[9]</a>, and in accord R individuals showed a decrease in this Basitarsal Index (BI) mean±s. e. noted in d (ANOVA: <i>F</i>_3,21 = 21.48, <i>P</i><0.00001, Fisher LSD: <i>P</i><0.00001; vs. between Vehicle and FK+R controls and between worker-destined groups <i>P</i>>0.50). e–g, rapamycin/FK506 pharmacology did not affect worker-destined bees. …”

Data Sheet 1_The effect of Traditional Chinese Medicine on patients undergoing targeted therapy for primary liver cancer: a systematic review and meta-analysis.docx by Hongting Yan (13242201)

“…</p>Results<p>Targeted therapy for liver cancer patients who received TCM treatment showed improvements in objective response rate (ORR) (RR, 1.49 [1.33-1.66], P < 0.0001), disease control rate (DCR) (RR, 1.32 [1.25,1.40], P < 0.0001), the 1-year survival (RR, 1.50 [1.20,1.88]; P = 0.0004) and Karnofsky Performance Status (KPS) (SMD, 1.34 [0.86,1.81]; P < 0.0001), and can reduce the incidence of adverse events, as well as to some extent decrease the production of tumor markers and related inflammatory factors.…”

Honokiol chemo-sensitizes pancreatic cancer cells to gemcitabine treatment. by Sumit Arora (297389)

“…Data are presented as relative percent viability with respect to untreated or honokiol only-treated cells to control for the growth suppressive effects of honokiol (mean± SD; n = 3. *, p<0.05). A significant decrease in IC₅₀ values of gemcitabine was observed in cells co-treated with honokiol. …”

Evaluating the role of Ht31 on synaptic plasticity. by Myungsook Kim (2166613)

“…<p>(A) Ht31 disruption of PKA anchoring decreases PKA activity and phosphorylation of downstream targets in the model. …”