CAR undergoes RIP by the γ-secretase complex. by Nadia Houri (451445)

“…Drug treatments resulted in accumulation of CAR CTF1 (20 kDa) and a decrease in CAR CTF2 (14 kDa) levels in a dose-dependent manner. …”

H-89 reduces the signal from RLuc8 in single cells. by Katie J. Herbst (263656)

“…Additional doses of H-89 decrease the signal further. (B) Channel intensity images (top) and pseudocolor images (bottom) of cells corresponding to (A) at t = 15 min (before H-89 addition) and t = 50 min (when signal has reached maximum inhibition).…”

Displacement plots of ethidium bromide-DNA complexes by polyamines. by Ayesha Kabir (436717)

“…<p>Relative fluorescence intensity decrease of ethidium bromide (1.2 μM)-DNA(12.0 μM) complex induced by the binding of (A) spermine with CP DNA(-▪-), EC DNA (-•-), ML DNA (-▴-) and (B) spermidine with CP DNA(-▪-), EC DNA (-•-), ML DNA (-▴-) conducted in 10 mM SHE buffer pH 7.0 at 293.15 K (Inset: The values of IC₅₀ of CP, EC and ML DNA shown as a bar graph).…”

Stress-induced cortisol responses in 5 dpf larvae. by Chen-Min Yeh (225051)

“…<p>(<b>A</b>) Cortisol response of 5 dpf zebrafish larvae to various stressors: non-exposed controls (N=11), temperature increase (N=8), temperature decrease (N=8), ammonia solution (50 mg ml^-1; N=11), pH shock (1 mM; N=10), osmotic shock (250 mM; N=10), EtOH (2%; N=11), and CuSO₄ (50 µM; N=12). …”

The N-terminus of PrP modulates mutant PrP metabolism. by Aarthi Ashok (262860)

“…The right panel shows the fate of unglycosylated PrP, without or with 5 µM MG132. (C) Lysates harvested after pulse labeling with S³⁵-methionine from cells expressing wtPrP, wtPrPΔN, PrP(H187R) and PrP(H187R)ΔN were separated into detergent soluble (S) and insoluble (P) fractions, immunoprecipitated, and analyzed by autoradiography. …”

Results of the hierarchical Kalman filter simulations of offset analgesia. by Malin Ramne (19996885)

Ginger inhibits cell growth and modulates angiogenic factors in ovarian cancer cells-6 by Jennifer Rhode (86654)

27_Clusters_excelFile by Kenneth D. Belanger (773857)

FGFR activation in mammary epithelial cells and breast cancer cells promotes macrophage recruitment. by Johanna R. Reed (306158)

Myocardin Family Members Drive Formation of Caveolae by Katarzyna K. Krawczyk (779848)

Relative diver effects – fixed distance and immediate return. by Luke C. Dickens (223801)

“…<p>Relative diver effects on estimated reef fish densities comparing counts over a fixed distance 50 m transect and counts along the tape immediately after deployment. …”

Amount and type of maternal dietary fat induced altered ACh-induced vaso-relaxation in the offspring. by Christopher J. Kelsall (173702)

“…<p>(A)–(D), Values are mean ± SD (n = 6/group) concentration which produced 50% maximum response (EC₅₀) such that increasing values on the y-axis correspond to decreasing vaso-relaxation responses. …”

Effects of different parameters on Rnf2 binding. by Nikolaj Dietrich (181521)

“…Densities, within each bin, depend on the number of peaks, whereas the color-coding corresponds to the average Rnf2<i>_Rest−/−</i>/Rnf2<i>_Wt</i> ratio with red, green and blue illustrating increased, unaffected, or decreased signal, respectively. …”

MIA pathway is required for liver and pancreas development. by Anna M. Sokol (5992973)

“…(B) Whole mount <i>in situ</i> hybridization demonstrates a decreased expression of <i>rbp2b</i> and the liver marker <i>ceruloplasmin</i> (<i>cp</i>), in the liver of <i>mia40a</i> larvae at 5 dpf. n: number of analysed individuals. …”

S15 Fig - by Marta Rudzite (15991136)

“…<p><b>Set of simulation outputs (A) corresponding to <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1011428#ppat.1011428.g005" target="_blank">Fig 5C</a> with non-lytic toxin-based interactions. …”

Intravesical MIF and MIF receptors mediate PAR4-induced bladder hyperalgesia. by Shaojing Ye (11320474)

“…A) In mice pre-treated with intravesical PBS, intravesical PAR4 peptide resulted in a marked and significant decrease in 50% threshold score when compared to scrambled peptide treatment. …”

Disruption of Astrocyte Communication by Carbenoxolone During Shockwave-Induced Stress by Serina Yan (22416354)

“…<p dir="ltr">This study investigates how carbenoxolone (CBX), a gap junction inhibitor, alters calcium signaling in astrocytes following laser-induced shockwave (LIS) injury. …”

OsMADS23 mediates ABA sensitivity and ABA-induced stomatal movement in rice. by Xingxing Li (321490)

“…Scale bars, 2 cm. <b>(D)</b> Decrease rate of shoot and root length in 1 μM ABA compared to mock on day 4. …”

Merlin negatively regulates SC NPC growth and glial differentiation in a Rac1- and ErbB2-dependent manner. by Cynthia Garcia (562261)

“…(<b>B</b>) Pharmacologic Rac1inhibition decreases <i>Nf2</i>−/− SC NPC neurosphere diameters (Vehicle: WT vs. …”

Reduced neutrophil influx after renal I/R in the mutant mice for collagen XV and XVIII. by Azadeh Zaferani (625709)

“…At day 1 after reperfusion double mutant mice showed a decreased number of neutrophils compared to WT mice (p<0.05). …”