RAGE blocking and APP inhibition synergistically reduce oxidative stress, apoptosis and rescue sequential gliocentric cell fate change in DS HNPs. by Jie Lu (139953)

“…(B) Graphs show the S100B stimulation for 24 hours dose dependently increase H₂O₂ production and decrease mitochondrial membrane potential which can be blocked by RAGE antibody (1 µg/ml) or dalteparin sodium (1 IU/ml) (<b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0022126#pone.0022126.s005" target="_blank">Figure S5A</a></b>). …”

K-Rta physically associates with SUMO. by Yoshihiro Izumiya (449433)

“…Increasing amounts of K-Rta Wt or K-RtaΔSIM3&5 (0.25, 0.5, or 1.0 ug) were cotransfected with SUMO. …”

Facile synthesis of narrow particle size distribution, high solid content, cationic polymer latexes by macroemulsion polymerization-based particle coagulation mechanism by Yang Bai (198601)

“…<p>In this study, a novel approach for preparing 50 wt% solid content cationic poly(methyl methacrylate) (PMMA) latexes with narrow particle size distribution (PSD) using macroemulsion polymerization was proposed. …”

Comparison of the rescue ability of Gas7 wild-type and mutant protein. by Bo-Tsang Huang (162584)

“…All plasmids were transiently transfected (0.5 µg) into 293 T cells. Western blot detected Gas7, GAPDH, and GFP. …”

The airway intrinsic BX-C code determines the outcome of <i>hh</i> signaling. by Ryo Matsuda (685668)

“…Note that Salm expression in DT shows a posterior-to-anterior decrease. Upon overexpression of <i>Ubx</i> (G), <i>abdA</i> (H) or <i>AbdB</i> (I), DTa1 becomes negative for Kni and positive for Salm (asterisks). …”

Data_Sheet_4_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

Data_Sheet_1_Unequal Impact of COVID-19 on Private and Academic Neurosurgical Workforce: Results of an International Survey.PDF by Sami Ridwan (11510080)

“…</p><p>Conclusion: The lockdown imposed in many countries by the COVID-19 outbreak called for immediate modification of working routine and resulted in a dramatic decrease of elective surgical procedures. …”

Data_Sheet_2_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

Data_Sheet_1_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

4-Phenyl-1,3-thiazole-2-amines as scaffolds for new antileishmanial agents by Carina Agostinho Rodrigues (5887349)

“…A target fishing study suggested that S-methyl-5-thioadenosine phosphorylase is a potential target to these compounds, which could be explored to enhance activity and decrease the potential toxic side effects. …”

Climatic factors driving vegetation declines in the 2005 and 2010 Amazon droughts by Wenqian Zhao (3937202)

“…The results showed that (i) in the Amazon vegetation greenness responded to precipitation, radiation and temperature, with apparent time lags for most averaging interval periods associated with vegetation index responses of 0–4, 0–9 and 0–6 months, respectively; (ii) on average, the three climatic factors without time lags explained 27.28±21.73% (mean±1 SD) of vegetation index variation in the Amazon basin, and this value increased by 12.22% and reached 39.50±27.85% when time lags were considered; (iii) vegetation greenness in this region in non-drought years was primarily affected by precipitation and shortwave radiation, and these two factors altogether accounted for 93.47% of the total explanation; and (iv) in the common epicenter of the two droughts, pixels with a significant variation in precipitation, radiation and temperature accounted for 36.68%, 40.07% and 10.40%, respectively, of all pixels showing a significant decrease in vegetation index in 2005, and 15.69%, 2.01% and 45.25% in 2010, respectively. …”

Table_1_In vitro investigation of the antiviral activity of propolis and chitosan nanoparticles against the genotype VII Newcastle disease virus.DOCX by Noura Alkhalefa (13387473)

“…The median tissue culture infectious dose (TCID50) assay demonstrated that the nanoparticles have antiviral effects after NDV exposure resulting in significant decrease in viral titer (TCID50) by 2, 2.66, and 2.5 log10 at 62 μg/ml of chitosan, 13 μg/ml of propolis, and 30 μg/ml of the propolis–chitosan mixture, respectively, compared with the control TCID50 value of 4 log10. …”

Data_Sheet_5_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

Table_1_In vitro investigation of the antiviral activity of propolis and chitosan nanoparticles against the genotype VII Newcastle disease virus.DOCX by Noura Alkhalefa (13387473)

“…The median tissue culture infectious dose (TCID50) assay demonstrated that the nanoparticles have antiviral effects after NDV exposure resulting in significant decrease in viral titer (TCID50) by 2, 2.66, and 2.5 log10 at 62 μg/ml of chitosan, 13 μg/ml of propolis, and 30 μg/ml of the propolis–chitosan mixture, respectively, compared with the control TCID50 value of 4 log10. …”

Data_Sheet_3_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

L1 overexpression in SENAs reduces the scar volume after transplantation into the compression-lesioned spinal cord of adult mice. by Yi-Fang Cui (227234)

“…(<b>C</b>) Immunofluorescence of a parasagittal section stained with antibodies against GFAP (red) at the lesion site six weeks after transplantation of L1 overexpressing SENAs (L1), wild-type (WT) SENAs, or sham-injection of PBS. Mean relative scar volumes ± SEM are displayed in the diagram (L1, n = 7; WT, n = 7, PBS, n = 5). …”

Effects of SNF1 pathway mutations on GFP-PTS1 distribution. by Xiao-Qing Zeng (103514)

“…Enlarged peroxisomes were more frequently observed in <i>ΔMosnf1</i> and <i>ΔMosak1ΔMotos3</i> than WT. Arrows point to peroxisomes. Bar  = 5 µm. (<b>B</b>) Colocalization of GFP-PST1-positive peroxisomes and CMAC-stained vacuoles. …”

The effects of C3 deficiency on inflammation and survival after LPS/D-GalN injection. by Shihui Sun (180042)

“…<p>(A) The response patterns to different ALT concentrations in C3^−/− and wt mice (n = 4–5). (B–D) The serum levels of proinflammatory cytokines after LPS/D-GalN injection. …”

Metronidazole-treated <i>Tg(Inta11:NTR)</i> larvae show defects in median fin fold mesenchyme migration, a reduction in median and pectoral fin fold size and a reduction in endoske... by Robert L. Lalonde (4840260)

“…Endoskeletal disc values are based on measurements of 5, 5, and 8 fins (n = 5 fins, n = 5 fins, n = 8 fins) for treatment controls and Inta11: NTR + MTZ larvae respectively. …”

Distal cue novelty task. by Desiree R. Seib (5249750)

“…<p>A) Rats decreased exploration of the objects over the 6 trials (Mauchly’s test P = 0.2; trial effect, F_5,135 = 44, P<0.001, partial η² = 0.62) and did not increase exploration upon changes to the distal context on trial 6 (trial 6 vs trials 1–4 all P<0.01, trial 6 vs trial 5 P = 0.3). …”