Blue fluorescent cGMP sensor Cygnus. by Yusuke Niino (253286)

“…(F) cGMP imaging in primary rat hippocampal neurons using Cygnus. A representative fluorescence image (upper) and a trace of the response to 50 µM SNAP (lower) are shown (<i>n</i> = 6). …”

Soluble RGMA.Fc selectively inhibits BMP induction of hepcidin promoter luciferase activity. by Qifang Wu (131118)

“…(<b>B</b>) Hep3B cells were transfected as indicated in Panel <b>A</b>. Transfected cells were incubated alone, with 25 ng/ml BMP6 ligand, or with 25 ng/mL BMP6 ligand plus 0.2 to 50 µg/ml RGMA.Fc or HJV.Fc as indicated followed by measurement of relative luciferase activity. …”

Fig 3 - by Aakash Pandey (17735915)

“…Range of bTB prevalence changes for 50% changes in harvest rates in Alpena County. The upper dashed line represents results for a 50% decrease in harvest rate, lower represents the result for a 50% increase in harvest rate and the solid line represents baseline predictions (maintaining harvest at current levels).…”

Data_Sheet_1_The Impacts of Climate Change on Land Hydroclimatology of the Laurentian Great Lakes Basin.PDF by Narayan K. Shrestha (13025667)

“…Minimum temperature is expected to increase in a higher rate than maximum temperature. Ensemble results from the hydrological model show projected decrease in snowpack (29–58%). …”

<i>Sting</i>^<i>Gt/Gt</i> mice display improve clearance of <i>S</i>. <i>aureus</i> following cutaneous challenge. by Philip O. Scumpia (4246900)

“…(B) Left panel shows Total Flux over 5 minutes, and Right panel shows Mean Radiance (Photons/second). * denotes p<0.05 by one way ANOVA with Tukey’s test for <i>Sting</i>^<i>Gt/Gt</i> mice when compared to WT mice at each time point and represents an n = 8 mice over two separate experiments. ** denotes p<0.05 by one-way ANOVA with Tukey’s test at each time point for <i>Myd88</i>^-/- mice when compared to WT mice at each time point and represents an n = 5 for <i>Myd88</i>^-/- compared to n = 8 WT mice. …”

Syndecan-1 Regulates Vascular Smooth Muscle Cell Phenotype by Somali Chaterji (527203)

“…Gene expression and western blotting studies indicated decreased levels of α-smooth muscle actin (α-SMA), calponin, and other vSMC-specific differentiation markers in S1KO relative to WT cells. …”

Nonlinear fits for expression levels with age of eight genes during Development. by Christopher T. Primiani (588504)

White shark relative decline in abundance. by Tobey H. Curtis (576240)

“…<p>Estimates of relative decline in abundance (filled circles) with 95% credible intervals (dashed lines) for any reference year between 1960 and 1986 assuming no change in observation effort (black plot), a 25% and 50% increase in observation effort (green and red plots, respectively), and a 25% and 50% decrease in observation effort (blue and purple plots, respectively). …”

Knockdown of p63 affects cellular morphology, proliferation and migration. by Ari Jon Arason (398271)

List of PCL compounds confirmed in dose-response assays. by Stella M. Bernardo (650493)

“…<p>*The arrow indicates whether a compound elicited an increase (inducer) or decrease (inhibitor) in expression levels, as measured by fold-response of the GFP-tagged protein.…”

MIGRATION AND COMMUTING IN THE AREAS OF INFLUENCE OF THE BRAZILIAN METROPOLISES by Carlos Lobo (4650766)

Expression patterns in the four expression clusters. by Hong Xu (71477)

Figure S1 - Fluphenazine Reduces Proteotoxicity in <i>C. elegans</i> and Mammalian Models of Alpha-1-Antitrypsin Deficiency by Jie Li (15030)

“…Animals treated with 50 µM Flu had a modest but statistically significantly (p<0.05) decrease in lifespan. …”

<i>fstr-1/2</i> RNAi speeds up <i>clk-1(−)</i> animals. by David Cristina (265223)

“…<i>fstr-1/2</i> RNAi treatment significantly reduced the average thrashing rate of wild-type animals and significantly increased the average thrashing rate of <i>clk-1(−)</i> mutants. WT subjected to control RNAi: 115.6±3.1 thrashes/min; WT subjected to <i>fstr-1/2</i> RNAi: 97.5±4.3 thrashes/min; <i>clk-1(−)</i> mutants subjected to control RNAi: 61.2±5 thrashes/min; <i>clk-1(−)</i> mutants subjected to <i>fstr-1/2</i> RNAi: 78.9±5.7 thrashes/min. …”

Activation of AMPK prevented drug-induced hepatocellular injury and hepatocyte depolarization. by Sun Woo Sophie Kang (3280878)

“…After hepatocytes were treated with various concentrations of acetaminophen (APAP) or diclofenac (Diclo), dose-viability response curves were obtained for (<b>A</b>) acetaminophen (1–20mM, 24hr) in rat hepatocytes, (<b>B</b>) diclofenac (50–800μM, 24hr) in rat hepatocytes, (<b>C</b>) acetaminophen (1–50mM, 24hr) in human hepatocytes, and (<b>D</b>) diclofenac (100–3000μM, 24hr) in human hepatocytes. …”

HAMLET-antibiotic combination treatment eradicates pneumococci during nasopharyngeal colonization. by Laura R. Marks (311432)

“…<p>(A and B) Mice were colonized with <i>S. pneumoniae</i> EF3030 for 48 hours, treated intranasally with various doses of gentamicin in the presence (red circles) or absence (black squares) of HAMLET (50 µg) for 6 hours, and the bacterial burden associated with the nasal lavage (A) and the nasopharyngeal tissue (B) was determined. …”

Supplementary Material for: Effects of roxadustat on thyroid profiles in patients and animals with chronic kidney disease by Li W. (3610583)

“…Methods In this retrospective study (2019-2023) at Shenzhen Second People's Hospital, patients were categorized based on TSH reduction during follow-up (≥50% decrease vs<50% decrease). Thyroid profiles, clinical symptoms, and laboratory indicators were analyzed. …”

Failure of adaptive mechanisms leads to cardiac dysfunction and reduction in adult life span of <i>dcerk¹</i>. by Niraj K. Nirala (424266)

Exogenous VEGF rescues <i>Yy1</i> cKO yolk sac defects. by Siyeon Rhee (390224)

“…<p>A–Y) WT and cKO embryos cultured from 8.5–9.5<i> dpc</i> in the presence (+VEGF) or absence (−VEGF) of VEGF. …”

HIV-1 CA mutant-NUP153_C binding and sensitivity to Trim-NUP153_C restriction or NUP153 depletion. by Kenneth A. Matreyek (469236)

“…Points are color-coded based on NUP153_C binding phenotype: grey, not significantly different from WT; white, significantly decreased from WT; black, significantly increased from WT. …”