Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice حسب Julie Decock (44558)

"…We have intercrossed Mmp8-null mice with the Polyoma virus middle T oncogene-driven (MMTV-PyMT) mouse model of mammary cancer to explore the effects of loss of MMP-8 on the incidence and progression of mammary carcinomas. …"

Cerebrospinal α‐Synuclein Oligomers Reflect Disease Motor Severity in DeNoPa Longitudinal Cohort حسب Nour K. Majbour (8809316)

Resveratrol-Elicited PKC Inhibition Counteracts NOX-Mediated Endothelial to Mesenchymal Transition in Human Retinal Endothelial Cells Exposed to High Glucose حسب Roberta Giordo (299595)

"…Treatment of HRECs with HG increased intracellular ROS levels and promoted phenotype shifting towards EndMT, evidenced by decreased expression of endothelial markers concomitant with increased expression of mesenchymal ones. …"

Angiotensin II AT1 receptor internalization, translocation and de novo synthesis modulate cytosolic and nuclear calcium in human vascular smooth muscle cells حسب Sleiman, S.

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Fanconi–Bickel Syndrome: A Review of the Mechanisms That Lead to Dysglycaemia حسب Sanaa Sharari (12561952)

"…<p dir="ltr">Accumulation of glycogen in the kidney and liver is the main feature of Fanconi–Bickel Syndrome (FBS), a rare disorder of carbohydrate metabolism inherited in an autosomal recessive manner due to SLC2A2 gene mutations. …"

Deep Learning for Dynamic Wildlife Monitoring: A Real-Time Approach حسب Abdul Basit Mughal (22929001)

"…The parameters of the fine-tuned YOLOv11 decreased by 30% relative to the previous version, resulting in a very small model size of 5.5 MB and reduced processing time. …"

Acute spasticity in malignant MCA stroke: a case report and review of literature حسب Muhammad Faizan (12710607)

"…However, an acute onset of spasticity at presentation is extremely rare. We report a case of a 40-year-old male patient who presented with spasticity accompanied by aphasia and decreased consciousness. …"

A Severe Case of Overlap of Morphea and Eosinophilic Fasciitis after Burn Injuries حسب Hania Sami (21436013)

"…<h3>Background</h3><p dir="ltr">Generalized morphea is a rare fibrosing skin illness that progresses from erythematous, violet‐colored skin patches to sclerotic plaques. …"

Simultaneous Bilateral Neck of Femur Fracture in a Young Adult with Underlying Metabolic Disturbances حسب Eslam Alkaramani (14570439)

"…<em>Conclusion</em>. We report this rare case of bilateral neck of femur fracture in a young adult after a generalized seizure attack with underlying metabolic disturbances. …"

Clinical characteristics and treatment outcomes of coats disease in a Saudi Arabian population حسب Al-Qahtani, Abdullah

"…Conclusion: Although rare, Coats disease is usually advanced at presentation and has a poor visual prognosis in the Saudi population, like in other populations. …"
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Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases حسب Yousef Yahia (19756989)

"…<h3>Background</h3><p dir="ltr">Mirizzi Syndrome (MS) is a rare complication of gallstone disease that poses diagnostic and management challenges.…"

A single-institution review of 157 patients presenting with benign and malignant tumors of the ampulla of Vater حسب Azar, Riad

"…Based on our finding that nearly half the patients with T1 tumors had positive lymph nodes, we recommend pancreaticoduodenectomy for any patient with biopsy proven adenocarcinoma who is a suitable candidate for surgery. With the exception of individuals with familial adenomatous polyposis (FAP), adenomas of the ampulla of Vater arise sporadically and rarely. …"
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Automated detection of posterior urethral valves in voiding cystourethrography images: A novel AI-Based pipeline for enhanced diagnosis and classification حسب Saidul Kabir (15302407)

"…</p><h3>Conclusion </h3><p dir="ltr">PUV detection from VCUG images through automated segmentation and processing can reduce subjectivity and decrease physician workloads. The proposed approach can serve as a foundation for future efforts to fully automate PUV diagnosis and follow-up.…"

PGAP3 Associated with Hyperphosphatasia with Mental Retardation Plays a Novel Role in Brain Morphogenesis and Neuronal Wiring at Early Development حسب Sahar I. Da’as (9631717)

"…Here, we report a novel homozygous nonsense mutation in PGAP3 (c.265C>T-p.Gln89*), in a 3-year-old boy with unique novel clinical features. …"

Successful minimally invasive management of nonvascular grade IV blunt renal trauma with complete transection in a 7-year-old girl حسب Zlatan Zvizdic (9212371)

"…We also present a brief literature review on this rare lesion in children.…"

The persistence of hippocampal-based memory requires protein synthesis mediated by the prion-like protein CPEB3 حسب Stephan, Joseph S.

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The Effect of Recombinant Anthrax Lethal Toxin on Breast Cancer Cell Motility, Adhesion, and Invasion حسب El Chami, Dana

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Geomorphological changes in the coastal area of Farasan Al-Kabir Island (Saudi Arabia) since mid Holocene based on a multi-proxy approach حسب Pavlopoulos, Kosmas

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Prostaglandin E2 regulates the level and stability of cyclooxygenase-2 mRNA through activation of p38 mitogen-activated protein kinase in interleukin-1β-treated human synovial fibr... حسب Faour, Wissam

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The contribution of autophagy in glioblastoma multiforme cells treated with human recombinant arginase I-induced arginine deprivation. (c2018) حسب El Jbeily, Elie

"…Protein analysis through western blots was conducted to check for the conversion/activation of LC3-I to LC3-II and for the activation of mtTOR to PmTOR. The activation of LC3-I peaked in control conditions (chloroquine treatment), considerably decreased in cells treated with the highest arginase concentration, then increased again in cells treated with both arginase at its highest concentration and chloroquine. mTOR is active in control cells, while at highest arginase concentration there is an inactivation of mTOR resulting in the activation of autophagy. …"
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