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17961
Figure S1 - Fluphenazine Reduces Proteotoxicity in <i>C. elegans</i> and Mammalian Models of Alpha-1-Antitrypsin Deficiency
Published 2014“…Animals treated with 50 µM Flu had a modest but statistically significantly (p<0.05) decrease in lifespan. …”
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17962
Activation of AMPK prevented drug-induced hepatocellular injury and hepatocyte depolarization.
Published 2016“…After hepatocytes were treated with various concentrations of acetaminophen (APAP) or diclofenac (Diclo), dose-viability response curves were obtained for (<b>A</b>) acetaminophen (1–20mM, 24hr) in rat hepatocytes, (<b>B</b>) diclofenac (50–800μM, 24hr) in rat hepatocytes, (<b>C</b>) acetaminophen (1–50mM, 24hr) in human hepatocytes, and (<b>D</b>) diclofenac (100–3000μM, 24hr) in human hepatocytes. …”
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17963
Supplementary Material for: Effects of roxadustat on thyroid profiles in patients and animals with chronic kidney disease
Published 2024“…Methods In this retrospective study (2019-2023) at Shenzhen Second People's Hospital, patients were categorized based on TSH reduction during follow-up (≥50% decrease vs<50% decrease). Thyroid profiles, clinical symptoms, and laboratory indicators were analyzed. …”
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17964
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17965
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17966
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17967
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17968
<i>In vitro</i> T2* measurement of macrophages labeled with iron oxide.
Published 2012“…The T2* of the FION-labeled macrophages was decreased when the incubation concentration reached 50 µg Fe/mL (9.09±6.02 ms), however, the T2* of the macrophages labeled with 100 (µg Fe/mL) Feridex (62.50±7.69 ms) was higher than that of the macrophages labeled 12.5 µg Fe/mL FIONs (33.33±6.02 ms).…”
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17969
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17970
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17971
Western blot showing LOX-12 expression:
Published 2012“…</b> (<b>C</b>) Michaelis-Menten plot of LOX-12 activity versus arachidonic acid concentration showing decrease in activity at different concentrations (0, 25, 50, 75,100 µM) of YWCS. …”
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17972
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17973
New insights into the limited thermotolerance of anhydrobiotic tardigrades
Published 2020“…Here, we investigate the effect of 1 week of high temperature exposures on desiccated tardigrades with the aim of elucidating whether exposure-times longer than 24 hours decrease survival even further. From our analyses we estimate a significant decrease in the 50% mortality temperature from 63ºC to 56ºC for <i>Ramazzottius varieornatus</i> exposed to high temperatures in the desiccated tun state for 24 hours and 1 week, respectively. …”
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17974
Nanobody treatment leads to changes in norovirus capsid morphology.
Published 2017“…Nano-26, Nano-85, and citrate caused a significant decrease in genome copy levels compared to Nano-14. …”
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17975
FigShare Figure 4. Targetable sites to introduce pathogenic variants with prime editors.
Published 2020“…<b>(a)</b> Total number of ClinVar pathogenic variants, broken down by mutation type (transition, transversion, insertion or deletion) and the decrease in the percentage that can be introduced with prime editing under different conditions. …”
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17976
Sec24D regulates intracellular Proinsulin abundance.
Published 2020“…(B) Densitometric quantification of the relative abundance of Sec24D in transiently transfected Min-6 cells indicate a decrease in Sec24D levels of ~50% when transfected with Sec24D-targeted siRNA vs. controls (n = 5, p = 0.0117). …”
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17977
Examination of human interference and abundance upon plants and animals species richness
Published 2016“…<p><b>Meta Data:</b></p> <p>1) Abundance Native Plants: This is a discrete variable. A 50 m transect was placed along the length of the pond area and the impermeable surface. …”
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17978
Characteristics induced by 2 weeks exposure of SRA01/04 cells to low-doses of H<sub>2</sub>O<sub>2</sub>.
Published 2013“…<p>A. Shows that cell viability (Left) of SRA01/04 cells decreases with increasing concentrations of H<sub>2</sub>O<sub>2</sub> as measured by the MTT assay (Mean± SD; n = 5.). …”
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17979
Cytochalasin Delocalizes VASP from the Leading Edge, Changing the F-Actin Network and Cell Shape
Published 2007“…<div><p>(A) Time-lapse images show that overexpressed EGFP-VASP, which is enriched at the leading edge before addition of 1.0 μM cytochalasin D (time: 1:00, left panel), becomes weaker at the leading edge ∼2 min after cytochalasin treatment (time: 2:50, middle panel). …”
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17980
S9 Fig -
Published 2021“…HFFs were infected with VACV at an MOI of 2 in the presence or absence of 50 μM PD0325901 for 24 h. A plaque assay was performed to measure virus titers. …”