Mice deficient in P2Y₁₂ are protected from global cerebral ischemia and also have decreased microglia surrounding areas of injury. by Corey M. Webster (442040)

“…<p>Following bilateral common carotid artery occlusion for 12 min followed by 3 d reperfusion, P2Y₁₂ deficient mice (P2Y₁₂^+/−) suffered less injury to hippocampal CA1 compared to wildtype (WT) mice. …”

Soil Carbon Stocks Decrease following Conversion of Secondary Forests to Rubber (<i>Hevea brasiliensis</i>) Plantations by Marleen de Blécourt (435325)

Decrease in sterol accumulation in NPC1 mutant cells expressing TgNCR1-hNPC1. by Bao Lige (113279)

Translocation of EHEC-Hly to mitochondria results in cytosolic cytochrome c release and ΔΨ_m decrease. by Martina Bielaszewska (79970)

“…The sizes of immunoreactive bands are indicated. (<b>C, D</b>) Intensities of the cytochrome c signals in mitochondrial (mito) and cytosolic (cyto) fractions shown in panels A and B were quantified in HBMEC (<b>C</b>) and Caco-2 cells (<b>D</b>) using densitometry, expressed in arbitrary densitometric units (DU) and are presented as means ± standard deviations from three independent experiments. * Significantly decreased (<i>p</i><0.05) compared to mitochondrial cytochrome c in control cells; ** significantly increased (<i>p</i><0.05) compared to cytosolic cytochrome c in control cells (unpaired Student's <i>t</i> test). …”

<i>c-REL</i> knockout leads to significantly decreased expression levels of NF-κB family member and cell cycle-associated genes. by Carsten Slotta (4326091)

“…<p><b>A:</b> qPCR analysis showing significantly decreased mRNA levels of NF-κB family members <i>RELA</i>, <i>NFKB1 (p50)</i>, <i>NFKB2</i> (<i>p52)</i>, <i>IKBKE</i> and <i>TBK1</i> in <i>c-REL</i> knockout cells compared to wildtype cells. …”

CRISPR/Cas9-mediated deletion of <i>c-REL</i> results in a decreased proliferation of HeLa Kyoto cell accompanied by strongly reduced amounts of histone H2B. by Carsten Slotta (4326091)

“…<b>C:</b> Flow cytometric analysis of Annexin V-stained <i>c-REL</i>^-/- and wt HeLa Kyoto cells revealed only slightly increased amounts of apoptotic cells upon <i>c</i>-REL deletion in comparison to wt. <b>D:</b> Flow cytometric analysis of histone H2B-mCherry showed a strongly decreased amount of the H2B protein in 41.48% of <i>c-REL</i>^-/- HeLa Kyoto cells, which was observable in only 8.67% of HeLa Kyoto wt cells.…”

Effects of suppression of cofilin activation or overexpresssion of TJ proteins on the capsaicin-induced cofilin dephosphorylation and decrease in occludin expression. by Tomoko Shiobara (486327)

Exposure to EtBr decreases mtRNA in rat striatal co-cultures, purified neuronal cultures, and astrocytes. by Emily Booth Warren (4276333)

“…Error bars reflect delta-method propagated +/-SEM, with level of significance determined following Dunn’s post-hoc test. 2D[<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0190456#pone.0190456.ref005" target="_blank">5</a>] = 5ng/ml EtBr for 2 days, 4D[<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0190456#pone.0190456.ref005" target="_blank">5</a>] = 5ng/ml EtBr for 4 days, 2D[<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0190456#pone.0190456.ref050" target="_blank">50</a>] = 50ng/ml EtBr for 2 days, 4D[<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0190456#pone.0190456.ref050" target="_blank">50</a>] = 50ng/ml EtBr for 4 days. …”

Decreased miR-29b/c in GC tissue samples. by He Cui (229445)

Rho kinase (ROCK) inhibitors promote neurite elongation of human model neurons. by Frank Roloff (695802)

Decreased ocular size lesions in dogs treated with oxfendazole. by Vito Colella (725841)

DualAG decreased TG synthesis in DIO mice. by Vijay R. More (4532392)

The TLR4 activator LPS decreases photoreceptor viability and reducesWnt-mediated protection from oxidative stress. by Hyun Yi (57741)

“…<p>(A) Muller glia-photoreceptor cultures were incubated for 24 hr in 0.4 mM H₂O₂ to induce oxidative stress, with and without recombinant Wnt3a (150 ng/ml) or the TLR4 activator LPS (5 and 50 µg/ml). …”

Inhibition of ACC leads to decreased de novo lipogenesis in both U87 and U87 EGFRvIII but reduced the number of U87 EGFRvIII cells to a greater extent. by Jessica E. C. Jones (541168)

Identification of novel, small molecule TTBK1 inhibitor which dose dependently decreases tau phosphorylation at S422. by Gregory M. Dillon (8681430)

Dynamics of a Stick−Jump Contact Line of Water Drops on a Strip Surface by Xueyun Zhang (507745)

“…A 2D model was applied to analyze the contact line motion on the patterned surfaces, which showed reasonable agreement with the experimental results.…”

IC₅₀s data of antimalarials against controls. by Winnie Okore (14139712)

Depletion of <i>cyd-1</i> leads to decreased oocyte quality and increased apoptosis without affecting the DNA damage response (DDR). by Umanshi Rautela (20235283)

Decreased dendritic spine density in the mature cortex of <i>Cln6^nclf</i> mice. by Jeremy P. Morgan (479017)

<i>In vitro</i> application of ARTN decreased ATF3 expression in GFRα3-positive neurons. by Ting Wang (16292)

“…<p>In control conditions, most GFRα3-positive neurons expressed ATF3 at 1 d (96.7±0.5%) (<b><i>A–C</i></b>, arrows) and 4 d (97.2±0.4%) (<b><i>G–I</i></b>; arrows) after plating. …”