Overexpression <i>TRIM37</i> enhances PEX5 protein stability by promoting PEX5 monoubiquitination. by Lai Jiang (2401513)

PV1 treatment ameliorates EAU. by Pedro Henrique Papotto (791904)

Downregulation of TRIM37 expression exacerbates pathological damage in the MS model. by Lai Jiang (2401513)

“…Scale bar = 50 μm. (h) qRT-PCR (n = 6) and <b>(i, j)</b> Western blot (n = 3) both showed a significant decrease in the <i>TRIM37</i> mRNA and protein levels in the LPC-induced MS model compared to the control group. * <i><i>P</i></i> < 0.05, ** <i><i>P</i></i> < 0.01, *** <i><i>P</i></i> < 0.001, **** <i><i>P</i></i> < 0.0001, ns = not significant.…”

Further optimisation and <i>in vitro</i> characterization of influenza A reporter viruses. by Monique I. Spronken (779529)

“…Silent mutations were introduced into the PA packaging region present in the PA CDS (mPR) and the dPR was decreased from 149 to 50 nucleotides (sPR). (B) Virus titres of the wild-type and eGFP reporter viruses based on data from three individually rescued viruses. …”

Temsirolimus Partially Rescues the Hutchinson-Gilford Progeria Cellular Phenotype by Diana Gabriel (3608093)

“…The <i>LMNA</i> mutation results in the deletion of 50 amino acids from the carboxy-terminal region of prelamin A, producing the truncated, farnesylated protein progerin. …”

Illustrations of the SeqFold2D network and the Stralign dataset. by Xiangyun Qiu (316117)

Surface-Enhanced Counter Electrode Materials for the Fabrication of Ultradurable Electrochromic Devices by Rana Ahmad (9329093)

“…During prolonged cycling (20,000 and 50,000 cycles), the overall total resistance of ECDs remains fairly unchanged, while the capacitance decreases due to a loss of the pseudocapacitive component associated with electrochromic molecules. …”

Quercetin inhibited ERS and mitigated HG+OGD/R treated HT22 injury through activating SIRT1 and suppressing PERK signaling. by Jing Yang (13969)

Overexpression <i>TRIM37</i> inhibits inflammatory infiltration and alleviates demyelination in EAE model mice. by Lai Jiang (2401513)

Dopamine D₃/D₂ Receptor Ligands Based on Cariprazine for the Treatment of Psychostimulant Use Disorders That May Be Dual Diagnosed with Affective Disorders by Emma S. Gogarnoiu (13206131)

“…Cariprazine and two lead analogues, <b>13a</b> and <b>13e</b>, decreased cocaine self-administration (FR2; 1–10 mg/kg, i.p.) in rats, suggesting that partial agonists/antagonists with modest D₃R/D₂R selectivity may be effective in treating PSUD and potentially comorbidities with other affective disorders.…”

Data_Sheet_1_Linkage analysis and residual heterozygotes derived near isogenic lines reveals a novel protein quantitative trait loci from a Glycine soja accession.docx by Yia Yang (13172682)

“…We identified two genomic regions based on recombination events which had significant increases of 0.65 and 0.72% in seed protein content without a significant decrease in seed oil content. A new Kompetitive allele-specific polymerase chain reaction (KASP) assay, which will be useful for introgression of this trait into modern elite G. max cultivars, was developed in one region. …”

Column-based Technology for CD9-HPLC Immunoaffinity Isolation of Serum Extracellular Vesicles by Jianhui Zhu (678784)

“…The CD9-HPLC-IAC method achieved EV isolation from 40 μL of serum in 30 min with a yield of 8.0 × 10⁹ EVs, where EVs were further processed with a postcolumn cleaning step using the 50 kDa molecular weight cut-off filter for the buffer exchange, concentration, and reduction of potentially coeluting serum proteins. …”

Nutritional profile of patients in a multidisciplinary treatment program for severe obesity and preoperative bariatric surgery by Fernanda Cristina Carvalho Mattos MAGNO (6380201)

“…Vegetables intake was high in all appointments in the pre-operative period and, although low, the whole grain products consumption has increased during the pre-operative period achieving 30% of the study population. CONCLUSION: There was a decrease in body weight, a trend in the decrease of the body mass index and waist circumference and quantitative and qualitative improvement of food consumption.…”

FOXO3a down-regulates <i>PRNP</i> expression by binding to its promoter. by Ting Liu (45625)

“…Compared with the control, the co-transfection with FOXO1 and FOXO3a led to a 10–30% decrease in luciferase units in 10% FBS medium, whereas a 30–45% decrease was detected when the cells were serum starved. …”

Experimental design used in broiler chickens. by Oumayma Arbani (21001472)

“…At 21 days of age, Groups A and B were challenged by oculo-nasal route with 10⁷ EID₅₀ of H9N2 strains, isolated respectively during 2016 and 2022. …”

Basic characteristics included in the study. by Juan Gu (288925)

“…Statistical analyses were conducted using Stata version 14.0. A fixed-effects model was applied if P > 0.1 and I² ≤ 50%; otherwise, a random-effects model was used to account for significant heterogeneity Publication bias was assessed using funnel plots and Egger’s test. …”

Publication bias of the risk of all groups. by Juan Gu (288925)

“…Statistical analyses were conducted using Stata version 14.0. A fixed-effects model was applied if P > 0.1 and I² ≤ 50%; otherwise, a random-effects model was used to account for significant heterogeneity Publication bias was assessed using funnel plots and Egger’s test. …”

Study selection process. by Juan Gu (288925)

“…Statistical analyses were conducted using Stata version 14.0. A fixed-effects model was applied if P > 0.1 and I² ≤ 50%; otherwise, a random-effects model was used to account for significant heterogeneity Publication bias was assessed using funnel plots and Egger’s test. …”

Chinese Herbal Medicine for Aspirin Resistance: A Systematic Review and Meta-Analysis by Hanyu Chen (2735152)

“…And one trial showed that CHM plus aspirin could decrease the National Institutes of Health Stroke Scale (NHISS) score (P<0.05) and increase the Barthel Index (BI) score (P<0.05). 4 trials stated that there were no adverse effects occurred in intervention group, and analysis showed significant difference of CHM or CHM plus aspirin in reducing the occurrence of adverse events (FE, RR = 0.22, 95%CI[0.13, 0.39], P<0.00001). 5 trials claimed that the CHM monotherapy and CHM adjunctive therapy for AR did not add the risk of bleeding (FE, RR = 0.50, 95%CI[0.20, 1.22], P = 0.13>0.05).…”

Structure of Phloroglucinol. by Hammad Ahmed (7526297)

“…Our data showed that PHL significantly decreased the formation of AGEs with an IC₅₀ value of 0.3mM. …”