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Multiple homologs of 16p12.1 genes contribute to neurodevelopmental defects in <i>Drosophila melanogaster</i> and <i>X</i>. <i>laevis</i>.
Published 2021“…Knockdown of <i>cdr2</i> (n = 54, two-tailed student’s t-test, *p = 7.75 ×10<sup>−4</sup>), <i>polr3e</i> (n = 37, *p = 1.97 ×10<sup>−13</sup>) and <i>mosmo</i> (n = 50, *p = 1.36 ×10<sup>−11</sup>) led to decreased face width, while knockdown of <i>polr3e</i> (*p = 3.29 ×10<sup>−16</sup>) and <i>mosmo</i> (*p = 1.47 ×10<sup>−8</sup>) led to decreased orofacial area. …”
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DataSheet_1_Decrease in Serum Urate Level Is Associated With Loss of Visceral Fat in Male Gout Patients.docx
Published 2021“…</p>Results<p>ULT resulted in a mean (standard deviation) decrease in SU level (464.22 ± 110.21 μmol/L at baseline, 360.93 ± 91.66 μmol/L at the final visit, p <0.001) accompanied by a decrease in median (interquartile range) VFA [97.30 (81.15–118.55) at baseline, 90.90 (75.85–110.05) at the final visit, p < 0.001]. …”
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DataSheet_1_Interventions to Decrease Carotid-Intima Media Thickness in Children and Adolescents With Type 1 Diabetes: A Systematic Review and Meta-Analysis.docx
Published 2022“…CIMT measurement was rated at a higher quality on all reliability domains in 3 (50%) studies. …”
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Homologs of 16p12.1 genes contribute towards neurodevelopmental defects through weak genetic interactions and combined independent effects.
Published 2021“…<p>(<b>A</b>) We generated eye-specific <i>GMR-GAL4</i> recombinant lines for the four 16p12.1 homologs to test a total of twelve pairwise interactions for modulation of eye defects. …”
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In <i>Drosophila</i> DSK and TO inhibits Gr64f gene transcription and optogenetic activation of Dsk-GAL4 neurons decreases the sensitivity of gustatory neurons in starved flies.
Published 2021“…(<b>F</b>) Expression pattern of <i>Dsk</i>-GAL4 in the brain revealed by anti-GFP (F1) and anti-DSK (F2). Scale bars, 50 μm. (<b>G</b>) Electrophysiological recordings reveal that starved flies (24 h) show increased sensitivity of GRNs compared with refed flies (fed 1.5 h after starvation) and optogenetic activation of <i>Dsk</i>-GAL4 neurons (30 min) decreases the sensitivity of gustatory neurons in starved flies (24 h). …”
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The primers related to FAM50A.
Published 2025“…Knockdown of FAM50A decreased cell proliferation ability, the proportion of EdU positive cells, and the number of CRC cell colonies, whereas overexpressing FAM50A promoted proliferative phenotypes. …”
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Table_1_Decreased synaptic vesicle glycoprotein 2A binding in a rodent model of familial Alzheimer's disease detected by [18F]SDM-16.DOCX
Published 2023“…</p>Conclusions<p>In conclusion, [<sup>18</sup>F]SDM-16 was used to detect decreased SV2A levels in the brain of APP/PS1 AD mouse model at one year old. …”
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Trial profile.
Published 2024“…<div><p>HIV acquisition risk with norethisterone (NET) enanthate (NET-EN) is reportedly less than for depo-medroxyprogesterone acetate intramuscular (DMPA-IM). We investigated the effects of these progestin-only injectable contraceptives on serum testosterone and sex hormone binding globulin (SHBG) levels, since these may play a role in sexual behavior and HIV acquisition. …”