Data_Sheet_1_Treatment Outcome of a Combined Dose-Escalated Treatment Regime With Helical TomoTherapy® and Active Raster-Scanning Carbon Ion Boost for Adenocarcinomas of the Head a... by Sati Akbaba (7213499)

“…While bimodal RT for ITAC resulted in a significantly decreased 3-year LC rate of 50 vs. 93% for each SGAC and SDAC (p < 0.01), no statistical significant survival differences could be identified across the three groups regarding OS (p = 0.08) and PFS (p = 0.063). 3-year OS was 88% for SGAC, 78% for SDAC and 67% for ITAC and 3-year PFS was 72% for SGAC, 53% for SDAC and 44% for ITAC, respectively. …”

Data_Sheet_2_Treatment Outcome of a Combined Dose-Escalated Treatment Regime With Helical TomoTherapy® and Active Raster-Scanning Carbon Ion Boost for Adenocarcinomas of the Head a... by Sati Akbaba (7213499)

“…While bimodal RT for ITAC resulted in a significantly decreased 3-year LC rate of 50 vs. 93% for each SGAC and SDAC (p < 0.01), no statistical significant survival differences could be identified across the three groups regarding OS (p = 0.08) and PFS (p = 0.063). 3-year OS was 88% for SGAC, 78% for SDAC and 67% for ITAC and 3-year PFS was 72% for SGAC, 53% for SDAC and 44% for ITAC, respectively. …”

Image_12_TGF-β2 Induces Gli1 in a Smad3-Dependent Manner Against Cerebral Ischemia/Reperfusion Injury After Isoflurane Post-conditioning in Rats.TIF by Li Peng (83452)

DataSheet1_Sodium Tanshinone IIA Sulfonate as a Potent IDO1/TDO2 Dual Inhibitor Enhances Anti-PD1 Therapy for Colorectal Cancer in Mice.pdf by Rongjie Zhang (5625083)

“…Here, we discovered that sodium tanshinone IIA sulfonate (STS), a sulfonate derived from tanshinone IIA (TSN), reduced the enzymatic activities of IDO1 and TDO2 with a half inhibitory concentration (IC₅₀) of less than 10 μM using enzymatic assays for natural product screening. …”

An investigation of the equine epidermal growth factor system during hyperinsulinemic laminitis - Fig 2 by Melody A. de Laat (7037468)

“…There was no immunostaining of the basement membrane. A: Bar = 50 μm, B: Bar = 50 μm, C and D: Bar = 20 μm.…”

table3_miRNome profiling of LSC-enriched CD34+CD38−CD26+ fraction in Ph+ CML-CP samples from Argentinean patients: a potential new pharmacogenomic tool.xlsx by María Sol Ruiz (9966293)

table2_miRNome profiling of LSC-enriched CD34+CD38−CD26+ fraction in Ph+ CML-CP samples from Argentinean patients: a potential new pharmacogenomic tool.xlsx by María Sol Ruiz (9966293)

table1_miRNome profiling of LSC-enriched CD34+CD38−CD26+ fraction in Ph+ CML-CP samples from Argentinean patients: a potential new pharmacogenomic tool.xlsx by María Sol Ruiz (9966293)

datasheet1_miRNome profiling of LSC-enriched CD34+CD38−CD26+ fraction in Ph+ CML-CP samples from Argentinean patients: a potential new pharmacogenomic tool.pdf by María Sol Ruiz (9966293)

Data Sheet 1_Dietary seaweed extract mitigates oxidative stress in Nile tilapia by modulating inflammatory response and gut microbiota.docx by Muhammad A. B. Siddik (6569957)

Treatment consequence and adverse events of cyclin-dependent kinase 4/6 inhibitors on patients with hormone receptor-positive, HER2-negative metastatic breast cancer: a systematic... by Hsiang-Ying Wu (22212274)

“…</p> <p>Eleven clinical trials published between 2015 and 2022 were included in our meta-analysis, with a total of 5572 eligible patients. This meta-analysis found that HR(+)/HER2(−) metastatic breast cancer treated with CDK4/6 inhibitors plus endocrine therapy can significantly improve progression-free survival(PFS) (HR: 0.55; <i>p</i> < 0.001), overall survival (OS) (HR: 0.79; <i>p</i> < 0.001), objective response rate (RR = 1.50; <i>p</i> < 0.001), clinical benefit rate (RR = 1.18; <i>p</i> < 0.001) and decrease progressive disease rate (RR = 0.49; <i>p</i> < 0.001). …”

Empirical results from the slime mould experiment. by James A. R. Marshall (7444412)

“…<p>Decreasing latencies to reach a food source as a function of the magnitude of the equal alternatives. …”

The filamin mutant forms localize to the Z-disc with different intensities. by Lucas A. B. Fisher (18865005)

datasheet1_Antihypertensive Effect of a Novel Angiotensin II Receptor Blocker Fluorophenyl Benzimidazole: Contribution of cGMP, Voltage-dependent Calcium Channels, and BKCa Channel... by Hina Iqbal (10496588)

“…</p><p>Results: FPD significantly decreased blood pressure in SHR. It relaxed superior mesenteric arteries in a concentration-dependent manner and significantly inhibited angiotensin II-induced contraction. …”

Data Sheet 1_Impact of early enteral nutrition on the prognosis of mechanically ventilated patients with chronic obstructive pulmonary disease: a retrospective cohort study based o... by Lamei Ouyang (20555782)

“…However, the EEN group exhibited a significantly shorter duration of mechanical ventilation (127.50 vs. 137.94 h, p = 0.023), reduced ICU length of stay (9.08 vs. 10.07 days, p < 0.01) and total hospitalization (14.64 vs. 16.63 days, p = 0.001). …”

Data Sheet 1_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.pdf... by Zilun Wu (18696883)

“…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. A stark disparity remains, with low-SDI regions accounting for over 67% of deaths and DALYs. …”

Tornado diagram of the one-way sensitivity analyses. by Iris W. A. Boot (18823769)

Data_Sheet_1_The Efficacy and Safety of Pirfenidone Combined With Immunosuppressant Therapy in Connective Tissue Disease-Associated Interstitial Lung Disease: A 24-Week Prospective... by Jiaqi Wang (369548)

“…However, in IIM patients with a non-UIP tendency, PFD displayed better therapeutic effects than the control (10.50 vs. 1.00%). …”

DataSheet1_Traditional Chinese Medicine Qingre Huoxue Treatment vs. the Combination of Methotrexate and Hydroxychloroquine for Active Rheumatoid Arthritis: A Multicenter, Double-Bl... by Xun Gong (82361)

“…The secondary outcome measures were treatment response rate according to American College of Rheumatology 20, 50, and 70% improvement criteria (ACR-20/50/70) and the rate of treatment-related adverse events (TRAEs). …”

Data Sheet 1_Lethal and sublethal effects of chemical and bio-insecticides on Spodoptera frugiperda adults: new perspectives for “attract-and-kill” control strategies.pdf by Nourhan A. El-Said (22434748)

“…In the current research, the lethal and sublethal impacts of five insecticides were evaluated against adult S. frugiperda, with a particular focus on chlorantraniliprole. Of the tested compounds, chlorantraniliprole revealed the highest toxicity (LC₅₀ = 1.29 mg/L). …”