BRD4 and LANA protein form LLPS. by Tomoki Inagaki (12903779)

Exercise improved lipid metabolism and insulin sensitivity in rats fed a high-fat diet by regulating glucose transporter 4 (GLUT4) and musclin expression by J. Yu (770485)

“…Rats fed with standard food served as normal control. We found that 8-week swimming intervention significantly decreased body weight (from 516.23±46.27 to 455.43±32.55 g) and visceral fat content (from 39.36±2.50 to 33.02±2.24 g) but increased insulin sensitivity index of the rats fed with a high-fat diet. …”

The Natural Anticancer Agent Plumbagin Induces Potent Cytotoxicity in MCF-7 Human Breast Cancer Cells by Inhibiting a PI-5 Kinase for ROS Generation by Ju-Hee Lee (135452)

“…In MCF7 human breast cancer cells, plumbagin significantly decreased the level of a human ortholog, 1, 4-phopshatidylinositol 5-kinase (PI5K)-1B, of yeast its3, and knockdown of PI5K-1B using siPI5K-1B increased the ROS level and decreased cell viability. …”

Data_Sheet_1_Perceived Social Support Protects Lonely People Against COVID-19 Anxiety: A Three-Wave Longitudinal Study in China.pdf by Jianjie Xu (9609167)

“…To examine the relationship between loneliness, perceived social support, and anxiety, we measured 222 Chinese participants’ (54.50% female, M_age = 31.53, SD = 8.17) trait loneliness, chronic anxiety before the outbreak, COVID-19 anxiety at the peak and decline stages of COVID-19, and their perceived social support across the three time points. …”

Disease Progression in MRL/lpr Lupus-Prone Mice Is Reduced by NCS 613, a Specific Cyclic Nucleotide Phosphodiesterase Type 4 (PDE4) Inhibitor by Thérèse Keravis (188522)

“…NCS 613 is a potent inhibitor, which is more selective for the PDE4C subtype (IC₅₀ = 1.4 nM) than the other subtypes (PDE4A, IC₅₀ = 44 nM; PDE4B, IC₅₀ = 48 nM; and PDE4D, IC₅₀ = 14 nM). …”

Metabolic factors, lifestyle habits, and possible polyneuropathy in early type 2 diabetes: A nationwide study of 5,249 patients in the Danish DD2 cohort by Diana H. Christensen (8599231)

“…Smoking: aPR 1.50 (1.24; 1.81) and lack of physical activity (0 vs ≥3 days/week): aPR 1.61 (1.39; 1.85) were also associated with DPN. …”

Comparison of CYP26A1, CYP26B1 and LRAT expression in normal colonic mucosa, primary colorectal cancer and lymph node metastasis. by Gordon T. Brown (532127)

Summary of mid/peri-pubertal EtOH exposure on miRNA and mRNA gene expression. by Sarah A. Prins (507483)

M002 treatment of neuroblastoma xenografts. by Lauren A. Gillory (469462)

“…In the SK-N-AS xenografts <b>A</b>, there was a significant decrease in tumor growth beginning at day 7 that continued to the end of the study. …”

Characterization of a novel antibiofilm effect of nitric oxide-releasing aspirin (NCX-4040) on <i>Candida albicans</i> isolates from denture stomatitis patients by Francisco Madariaga-Venegas (4020002)

“…<i>albicans</i>, making them promising candidates for treatment. In this study, we evaluated the antifungal/antibiofilm effect of a nitric-oxide releasing aspirin (NO-ASA) on <i>C</i>. …”

DataSheet_1_Treating performance of a commercial-scale constructed wetland system for aquaculture effluents from intensive inland Micropterus salmoides farm.docx by Bing Li (43671)

“…Thus, it is highly necessary to treat the effluents from inland fish farm. In this study, we built a commercial-scale integrated constructed wetland (CW) system with vertical subsurface flow, and monitored the purifying effect. …”

Data_Sheet_1_Computer-Based Executive Function Training for Combat Veterans With PTSD: A Pilot Clinical Trial Assessing Feasibility and Predictors of Dropout.docx by Ashley N. Clausen (3109596)

“…Further, these treatments do not directly target associated neuropsychological deficits. Here, we describe the methods and feasibility for computer-based executive function training (EFT), a potential alternative or adjunctive PTSD treatment.…”

Table 1_The role of serum albumin and albumin-related nutritional indices in predicting post-stroke cognitive impairment: a systematic review and meta-analysis.docx by Yan-qiu Wang (20565725)

“…We systematically searched six databases with a time frame from the date of database establishment to March 29, 2025. …”

Presentation_1_Lateral Preoptic Area Neurons Activated by Angiotensin-(1–7) Increase Intravesical Pressure: A Novel Feature in Central Micturition Control.pptx by Gustavo B. Lamy (11111085)

“…Unilateral or bilateral injections of A-779 into the LPA decreased IP (−15.88 ± 2.76 and −27.30 ± 3.40%, respectively) and elicited no changes in MAP, HR, and RC. …”

Table 4_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.docx by Tien Le (634791)

Table 5_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.docx by Tien Le (634791)

Protons cause a greater increase in persistent sodium current in C373F/E1784K Na_V1.5. by Colin H. Peters (4430245)

“…The E1784K mutant increases the fraction of charge which recovers with the fast time constant of recovery and decreases the fraction of slow charge return. (<b>F <i>inset</i></b>) To measure the rate of gating current deactivation, we depolarized cells to 0mV (c) following a conditioning pulse to 0mV (a) and a recovery pulse of variable length to -150mV (b).…”

Analgesic prescriptions received by patients before commencing the BOA model of care for osteoarthritis: a Swedish national registry study with matched reference and clinical guide... by Allan Abbott (6032138)

“…Since guideline publication, the proportion of the OA cohort having no dispensed prescription analgesics prior to non-pharmacological primary care intervention concordantly increased by 5.0% (95% CI 4.2–5.9). Furthermore, dispensed prescriptions concordantly decreased for non-selective NSAIDs –8.6% (CI –9.6 to –7.6), weak opioids –6.8% (CI –7.7 to –5.9), glucosamine –9.5% (CI –9.8 to –8.8). and hyaluronic acid –1.6% (CI –1.8 to –1.5) but discordantly increased for strong opioids 2.8% (CI 2.1–3.4) and glucocorticoid intra-articular injection for hip OA 2.1% (CI 1.0–3.1).…”

Is India ready for mental health apps (MHApps)? A quantitative-qualitative exploration of caregivers’ perspective on smartphone-based solutions for managing severe mental illnesses... by Koushik Sinha Deb (5770781)

Table 1_Manure substitution for chemical nitrogen enhances soil quality without compromising maize yield: a short-term field experiment in Northeast China.xlsx by Chao Zhou (471522)

“…Nonetheless, how organic manure substitution regulates microbial communities to influence soil quality and crop yield remains unclear. </p>Methods<p>A one-year field experiment comprising four organic manure substitution rates (25%, 50%, 75%, and 100%) along with a no-substitution control was conducted. …”