VPA and NAM treatment modulates H3K27 acetylation at the promoters of myeloid specific genes. by Marije Bartels (532852)

“…Data represent a Venn diagram comparing the number of genes identified based on a >2-fold increase or decrease in H3K27 acetylation levels compared to the control (A). …”

Pituitary Adenylate Cyclase Activating Peptide Deficient Mice Exhibit Impaired Thymic and Extrathymic Regulatory T Cell Proliferation during EAE by Yossan-Var Tan (322523)

“…In addition to these Treg alterations, a specific reduction of Th2 cells (about 4-fold) was observed in the lymph nodes in PACAP KO mice, with no effects on Th1 and Th17 subsets, whereas in the CNS, Th1 and Th17 cells were increased and Th2 decreased. …”

Table_1_Effect of Abdominal Circumference on the Irradiated Bowel Volume in Pelvic Radiotherapy for Rectal Cancer Patients: Implications for the Radiotherapy-Related Intestinal Tox... by Gang Wang (36685)

“…In adjuvant radiotherapy patients, we further discovered the threshold effect between AC and irradiated bowel volume, as AC was greater than the inflection point (about 71 cm), irradiated bowel volume decreased rapidly with the increase in AC. t-test showed that in patients with small AC (<71 cm), the irradiated bowel volume was significantly higher than that of patients with medium-large AC (≥71 cm). …”

Macrophages Have Distinct Transcriptional Responses to Vacuolar and Cytosolic L. monocytogenes Infection by Jess H Leber (4401)

“…Red indicates an increase in RNA abundance relative to uninfected macrophages, and green indicates a decrease. Genes identified by SAM and at least 4-fold induced in WT macrophages by <i>hly− L. monocytogenes</i> are indicated as targets of the “Vacuolar Response”. …”

The MEDII-associated mesoderm suppressing activity is found within the small molecular weight components of the medium. by James N. Hughes (319868)

“…Aggregates were transferred to unsupplemented medium or medium supplemented with 50% MEDII, 50% E or R and cultured for a further 2 days before reduction to a single cell suspension. …”

<i>In silico</i> inflammation profiles of aging in human tissues: Sex-specific lymphocyte signatures in skin. by William R. Swindell (175427)

“…Dark red colors indicate cases in which signature transcripts for a given cell population increase with age (i.e., the ratio of age-increased to age-decreased signature transcripts is greater than one). …”

Data Sheet 1_Impact of fluoxetine exposure on Lymnaea stagnalis and its developing eggs: integrating untargeted lipidomics, targeted metabolomics, and classical risk assessment.doc... by Diana Ilyaskina (20667155)

“…In the albumen gland, we detected a decrease of key lipid classes, including sphingomyelins and fatty acids, which can be linked with impaired egg quality. …”

SRM measurements of a subset of <i>C. jejuni</i> metabolic enzymes. by Xiaoyun Liu (154889)

“…</p>3<p>Fold change of fragment ion intensities between the 2 h and 20 h samples; negative values denote decreased levels in the 20 h samples.…”

Gas exchanges and production of watermelon plant under salinity management and nitrogen fertilization by Saulo Soares da Silva (7291103)

“…The watermelon plant expresses a greater sensitivity to saline stress in the vegetative and flowering phases, a situation that results in a decreased fruit size.…”

The effects of PC1, PC2 and IFT88 siRNA knockdown on hASC primary cilia. by Josephine C. Bodle (584791)

“…Cilia expression on hASC: (a) Non-targeting scramble siRNA baseline cilia expression on approximately 50% of the hASC population (b) PC1 and (c) PC2 knockdown conditions express more cilia observed in a curved conformation and a minimal decrease in cilia population frequency, (d) IFT88 knockdown confers a reduction in cilia frequency on the hASC population. …”

Effect of RAMP1 mRNA knockdown on TT cells. by Aditya J. Desai (508657)

“…<p>(A) mRNA expression levels of RAMP1, RAMP2 and CaSR in TT cells transfected with RAMP1 or scrambled siRNA, 72 hr post-transfection expressed as fold change normalised to Actβ. …”

Induction of intracellular metabolic activators by sofosbuvir. by Yongyut Pewkliang (4799217)

“…The gene expression was shown as fold-changes over the corresponding untreated groups. imHC and Huh7 were infected with HCVcc (genotype 2a) at MOI 1 and subsequently exposed to various concentrations of sofosbuvir for 7 days. …”

Data Sheet 1_Long-term outcomes according to absolute value vs. percentage reduction in low-density lipoprotein cholesterol levels after acute myocardial infarction.pdf by Kyung Hoon Cho (12176516)

“…In a multivariable Cox time-to-event analysis with LDL-C < 50% reduction from baseline as the reference, ≥50% LDL-C reduction from baseline was independently associated with a decreased incidence of MACE (adjusted hazard ratio, 0.76; 95% confidence interval, 0.62–0.92).…”

Chromatin relaxation affects spliceosome recruitment to nascent RNA and binding of splicing factors to ncRNAs. by Ignacio E. Schor (120406)

“…Each junction was analyzed separately, and for each junction genes included in the analysis (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0048084#s3" target="_blank">Materials and Methods</a>) were divided into categories of increased (Up), decreased (Down) or unchanged (less than 2-fold change in any direction) U2AF65 counts in a region of +/−100 nt around the corresponding junction. …”

VAPB is required for tumor growth <i>in vivo</i>. by Meghana Rao (130226)

Correlation of virus and cell morphology during the time course of MARV infection. by Sonja Welsch (196838)

Sequential Injection Analysis of Butyrylcholinesterase Using Butyrylcholine Ion-Selective Electrode Detector (Supporting Information) by Narimasa KOIZUMI (13719592)

“…In the present SIA method using the BuCh-ISE detector based on <i>α</i>-cyclodextrin membrane, BChE in the concentration range of 0.015–0.50 units/mL was determined at a BuCh concentration of 2.0 mmol dm⁻³ and a reaction time of 5.0 min. …”

Effect of Squeeze Casting on Microhardness and Microstructure of Al-3Cu-xSi Alloy by Ronaldo Oliveira (7453877)

“…This process provides changes in the microstructure which lead to changes in the mechanical properties of the material such as the increase in the microhardness of the processed alloy. alloys Al-5,5% Si-3% Cu, Al-7,5% Si-3% and Al-9% Si-3% Cu alloys were solidified by the squeeze casting process to analyze the microstructural and microhardness variations. Pressures of 0 MPa, 50 MPa, 100 MPa and 150 Mpa were used. In general, with increasing pressure and composition, the λ2 values decrease from the metal/mold interface, especially at pressures of 150 MPa and Composition of 9%Si, on the other hand the increase of these variables leads to the formation of more phases Al2Cu metastable that have a decrease in the Microhardness of the material, in addition to the formation of other phases due to the proximity to the eutetic.…”

NF-κβ, COX, and ROS involvement in EP bridge formation. by Brett G. Zani (254541)

“…<b>C–D:</b> SC-514 or indomethacin (INDO, 50 µM), a COX pathway inhibitor, caused ∼2–3 fold increases in EP bridges, arrows denote EP bridges, for both EPs/ECs and EPs/FBs after 48 h, n = 6−8. …”

Supplementary Material for: Eculizumab Modifies Outcomes in Adults with Atypical Hemolytic Uremic Syndrome with Acute Kidney Injury by Cao M. (4161253)

“…<b><i>Conclusion:</i></b> Eculizumab shows greater efficacy than PE/PI alone for the treatment of adult aHUS patients with AKI. …”