Table_11_Colistin Resistant A. baumannii: Genomic and Transcriptomic Traits Acquired Under Colistin Therapy.XLSX by Viviana Cafiso (188805)

“…The transcript analysis of the “COL-R related genes” and the RNA-seq data confirmed pmrCAB over-expression responsible for a greater positive net cell-charge, and lpxACD under-expression in COL-R causing a decreased LPS production, as main mechanisms of colistin resistance. …”

Comparisons of the studied mutations to a canonical GST from S. japonicum. by Aleksi Sutinen (10039145)

Aberrant Apoptotic Response of Colorectal Cancer Cells to Novel Nucleoside Analogues by Leonie Harmse (798112)

“…Despite marginal changes to the mitochondrial membrane potential, all three nucleosides caused a significant increase in cytosolic cytochrome c (<i>p</i>>0.05), with a corresponding decrease in mitochondrial cytochrome c. …”

<i>Kdm6a</i>^<i>-/-</i> cells exhibit dysregulated chondrogenesis. by Christine W. Gao (18794576)

Inhibitory synapses control decorrelation between <i>U</i>_<i>e</i> and mean noisy input. by Scott Rich (9873638)

“…<p><b>A–D</b>: Plots of the Pearson correlation coefficient between <i>U</i>_<i>e</i> (during baseline activity) and the mean (over all neurons during baseline activity) noisy input to the microcircuit as a function of the input correlation <i>c</i> (x-axis) and synaptic strengths (color coding). …”

DataSheet_1_Heritability and circulating concentrations of pregnancy-associated plasma protein-A and stanniocalcin-2 in elderly monozygotic and dizygotic twins.pdf by Rikke Hjortebjerg (16010939)

Bayesian estimate of the effective reproduction number <i>R_e</i> over time (from simulated data). by Remco Bouckaert (550308)

“…<p>Towards the end of the 3.5 years of the underlying epidemic process, <i>R_e</i> decreases below 1, which indicates a declining epidemic.…”

DYRK2 Negatively Regulates Cardiomyocyte Growth by Mediating Repressor Function of GSK-3β on eIF2Bε by Celine S. Weiss (453817)

“…</p><p>Results</p><p>(1) Under baseline conditions eIF2Bε transgenic mice showed no difference in cardiac phenotype compared to wild type, whereas in the mutant eIF2Bε-S⁵³⁵A an increase in LV/tibia length (7.5±0.4 mg/mm vs. 6.2±0.2 mg/mm, p<0.001) and cardiomyocyte cross sectional area (13004±570 vs. 10843±347 RU, p<0.01) was observed. (2) Cardiac overexpression of eIF2Bε did not change the response of the heart to pathologic stress induced by chronic isoproterenol treatment. (3) Cardiac overexpression of the eIF2Bε transgene was followed by overexpression of DYRK2 which is known to prime the inhibitory action of GSK-3β on eIF2Bε, while DYRK1A and GSK-3β itself were not increased. (4) In C57BL/6 mice after 48 h of isoproterenol-stimulation or aortic banding, eIF2Bε was increased and DYRK2 was concomitantly decreased. (5) In line with these in vivo findings, siRNA knockdown of DYRK2 in cultured cardiomyocytes resulted in decreased levels of p(S535)- eIF2Bε, (6) whereas adenoviral induced overexpression of DYRK2 was accompanied by clearly increased phosphorylation of eIF2Bε, indicating a coordinated response pattern (7) Adenoviral induced overexpression of DYRK2 leads to significantly reduced cardiomyocyte size and diminishes hypertrophic response to adrenergic stimulation.…”

Convergence (i.e., declining dissimilarity) of butterfly community and plant community within degraded sites to reference sites over time. by John T. Delaney (3335448)

Data_Sheet_1_Repurposing Ellipticine Hydrochloride to Combat Colistin-Resistant Extraintestinal Pathogenic E. coli (ExPEC).doc by Hao Lu (354247)

“…EH treatment significantly decreased the levels of a variety of pro-inflammatory factors, such as TNF-α and IL-6. …”

Glycemic levels measured for 3 hours from the extracorporeal circulation of perfused intestinal segment. by Matteo Dell’Anno (10724418)

The eNOS immunohistochemical staining of rat corpus cavernosum in NC, BIIAL, HFD, BCH and MS groups after 12 weeks. by Chao Hu (293389)

“…<p>Sections were made transversal to the penile axis. (A) Normal eNOS expression was observed in the NC group. …”

Physiotherapeutic approach for pain and quality of life of a hemophilic patient. Case report by Matheus Santos Gomes Jorge (4717800)

“…Patient was submitted to eight physiotherapy sessions, once a week, with mean duration of 50 minutes, between May and June 2015. …”

Potency and production of the three main neural cell lineages from E11.5 and P0 NS upon differentiation. by Lorelei D. Shoemaker (253366)

“…Significant differences in the generation of di- and multi-potent NS existed between E11.5 (G) and P0 (H) NS cultures, including an increase in P0 NS containing only O/A at Day 7 (p<0.05), and decreases in tripotent P0 NS at Day 7 (p<0.05) and at Day 14 (p<0.01). …”

CSF N-Glycan Profiles to Investigate Biomarkers in Brain Developmental Disorders: Application to Leukodystrophies Related to eIF2B Mutations by Anne Fogli (138515)

“…We investigated the CSF glycome of eIF2B-mutated patients and age-matched normal individuals in order to further characterize the glycosylation defect for possible use as a biomarker.…”

Table_1_Lactate Dehydrogenase as a Potential Therapeutic Drug Target to Control Babesia bigemina.docx by Lan He (219448)

“…Gossypol has a significant (P < 0.0001) inhibitory effect on the in vitro growth of B. bigemina, with IC₅₀ of 43.97 mM after 72 h of treatment. …”

Image_1_Lactate Dehydrogenase as a Potential Therapeutic Drug Target to Control Babesia bigemina.tif by Lan He (219448)

“…Gossypol has a significant (P < 0.0001) inhibitory effect on the in vitro growth of B. bigemina, with IC₅₀ of 43.97 mM after 72 h of treatment. …”

Repression of let-7a and let-7b is dependent on ATM phosphorylation of p53. by Anthony D. Saleh (342299)

Overall structure of GDAP1. by Aleksi Sutinen (10039145)

SAXS analysis. by Aleksi Sutinen (10039145)