Lifespan of long-lived mitochondrial mutants is dependent on DAF-16 interacting proteins IMB-2, CST-1/CST-2 and BAR-1. by Megan M. Senchuk (4925752)

“…Knockdown of the protein kinase <i>cst-1/cst-2</i> using RNAi also decreases the lifespan of <i>clk-1</i> (<b>D</b>), <i>isp-1</i> (<b>E</b>)and <i>nuo-6</i> (<b>F</b>) mutants. …”

Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2‑Related Factor 2 (KEAP1:NRF2) Protein–Protein Interaction with High Cell Potency Identi... by Thomas G. Davies (2606863)

NRF2 positively modulates CSCC cellular malignant phenotypes. by Jun-Qi Ma (135472)

“…<p>A, D, G and J: Cell apoptosis, Proliferation, Migration and invasion in Siha cells, respectively (Normal controls). B, E, H and K: a Knockdown of NRF2 increased cell apoptosis, decreased cell proliferation, migration and invasion, which significantly decreased malignant phenotypes of Siha cells. …”

CO and O₂ Binding to Pseudo-tetradentate Ligand−Copper(I) Complexes with a Variable N-Donor Moiety: Kinetic/Thermodynamic Investigation Reveals Ligand-Induced Changes in... by Heather R. Lucas (2258476)

“…The change in mechanism was not simply related to alterations in ^DLCu^II/I geometries or the order in which O₂ and THF coordinate. …”

CO and O₂ Binding to Pseudo-tetradentate Ligand−Copper(I) Complexes with a Variable N-Donor Moiety: Kinetic/Thermodynamic Investigation Reveals Ligand-Induced Changes in... by Heather R. Lucas (2258476)

“…The change in mechanism was not simply related to alterations in ^DLCu^II/I geometries or the order in which O₂ and THF coordinate. …”

CO and O₂ Binding to Pseudo-tetradentate Ligand−Copper(I) Complexes with a Variable N-Donor Moiety: Kinetic/Thermodynamic Investigation Reveals Ligand-Induced Changes in... by Heather R. Lucas (2258476)

“…The change in mechanism was not simply related to alterations in ^DLCu^II/I geometries or the order in which O₂ and THF coordinate. …”

Chronic Sleep Deprivation-Induced Proteome Changes in Astrocytes of the Rat Hypothalamus by Jae-Hong Kim (124622)

“…Comparisons of the proteome profiles of hypothalamic astrocytes revealed that chronic partial SD increased (≥1.5-fold) 89 proteins and decreased (≤0.7-fold) 50 proteins; these changes in protein expression were validated by western blot or immunohistochemistry. …”

Chronic Sleep Deprivation-Induced Proteome Changes in Astrocytes of the Rat Hypothalamus by Jae-Hong Kim (124622)

“…Comparisons of the proteome profiles of hypothalamic astrocytes revealed that chronic partial SD increased (≥1.5-fold) 89 proteins and decreased (≤0.7-fold) 50 proteins; these changes in protein expression were validated by western blot or immunohistochemistry. …”

Chronic Sleep Deprivation-Induced Proteome Changes in Astrocytes of the Rat Hypothalamus by Jae-Hong Kim (124622)

“…Comparisons of the proteome profiles of hypothalamic astrocytes revealed that chronic partial SD increased (≥1.5-fold) 89 proteins and decreased (≤0.7-fold) 50 proteins; these changes in protein expression were validated by western blot or immunohistochemistry. …”

Chronic Sleep Deprivation-Induced Proteome Changes in Astrocytes of the Rat Hypothalamus by Jae-Hong Kim (124622)

“…Comparisons of the proteome profiles of hypothalamic astrocytes revealed that chronic partial SD increased (≥1.5-fold) 89 proteins and decreased (≤0.7-fold) 50 proteins; these changes in protein expression were validated by western blot or immunohistochemistry. …”

Effects of chlorpyrifos on the crustacean <i>Litopenaeus vannamei</i> by Edisson Duarte-Restrepo (8703723)

“…In addition, inhibition of acetylcholinesterase (AChE) was determined in the brain. LC₅₀ (96-hours) was 2.10 μg/L of chlorpyrifos. …”

Reversal of GABAergic postsynaptic currents by the ANO2 inhibitor. by Weiping Zhang (311523)

“…<b>(C)</b> During the continued presence of the ANO2 inhibitor, virtually all postsynaptic currents reverse to positive polarity (Cl^- influx) indicating that GABAergic synapses experience an E_Cl more negative than V_hold. …”

Determination of substrate binding affinity of PKM2 variants. by Suparno Nandi (7285886)

“…(D-F) PEP binding affinities of (D) PKM2 R106A (E) PKM2 N70D (F) PKM2 N75L in the absence and presence of the AAs (color scheme for the AAs is identical to (C)). …”

Involvement of ANO2 in depolarization-induced depression of inhibition. by Weiping Zhang (311523)

“…<i>Lower traces</i>: postsynaptic currents, recorded immediately after the climbing-fiber stimulation, displayed decreased amplitudes. <b>(F)</b> IPSCs recorded from a Purkinje cell of an Ano2^-/—mouse before <i>(upper traces)</i> and immediately after <i>(lower traces)</i> CF-activation. …”

The influence of fluoxetine treatment on <i>P</i>. <i>berghei</i> pathogenesis. by Li Gao (131516)

H₂S protected human pulmonary artery endothelial cells (HPAECs) from O₂-induced toxicity. by Arul Vadivel (424484)

“…(<b>E</b>) After 48 hours culture in hyperoxia (95%), ROS activity evaluated by measuring the dichlorofluorescein (DCF) shows that hyperoxia increases the ROS production in HPAECs, treatment with GYY4137 significantly decreased the ROS (n = 6/group, *P<0.005 Hyperoxia vs O₂+H₂S).…”

Potassium Zinc Borohydrides Containing Triangular [Zn(BH₄)₃]⁻ and Tetrahedral [Zn(BH₄)_<i>x</i>Cl_4–<i>x</i>]<sup>2–... by Radovan Černý (1441396)

“…Tetragonal K₃Zn(BH₄)_<i>x</i>Cl_5–<i>x</i> is a substitutional and deformation variant of the tetragonal (<i>I</i>4/<i>mcm</i>) Cs₃CoCl₅ structure type possibly with the space group <i>P</i>4₂/<i>ncm</i>. K₃Zn(BH₄)_<i>x</i>Cl_5–<i>x</i> decomposes nearly at the same temperature as KZn(BH₄)₃, i.e., at ∼400 K, with the formation of K₂Zn(BH₄)_<i>x</i>Cl_4–<i>x</i> and KBH₄, indicating that the compound is an adduct of the two latter compounds.…”

Potassium Zinc Borohydrides Containing Triangular [Zn(BH₄)₃]⁻ and Tetrahedral [Zn(BH₄)_<i>x</i>Cl_4–<i>x</i>]<sup>2–... by Radovan Černý (1441396)

“…Tetragonal K₃Zn(BH₄)_<i>x</i>Cl_5–<i>x</i> is a substitutional and deformation variant of the tetragonal (<i>I</i>4/<i>mcm</i>) Cs₃CoCl₅ structure type possibly with the space group <i>P</i>4₂/<i>ncm</i>. K₃Zn(BH₄)_<i>x</i>Cl_5–<i>x</i> decomposes nearly at the same temperature as KZn(BH₄)₃, i.e., at ∼400 K, with the formation of K₂Zn(BH₄)_<i>x</i>Cl_4–<i>x</i> and KBH₄, indicating that the compound is an adduct of the two latter compounds.…”

G6 Reduces the Levels of Vimentin Protein within T98G-derived Tumors. by Rebekah Baskin (622078)

“…Scale bars represent either 50 µm (top panels) or 10 µm (bottom panels). D) The intensity of vimentin staining was quantified via relative pixel counting and the average pixel counts were then plotted as a function treatment group. …”

LBH589 treatment inhibited the growth of SK-NEP-1 xenograft tumors in nude mice. by Tao Yan-Fang (770096)

“…Down regulation of Bcl-2 and cleaved PARP and caspase 9 was observed after 24 hours of treatment with 50nM and 100nM LBH589. …”