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19881
The effect of dopamine on Δψ<sub>m</sub> and [Ca<sup>2+</sup>]<sub>c</sub> in midbrain neurons and astrocytes.
Published 2013“…Furthermore this increase in [Ca<sup>2+</sup>]<sub>c</sub> is associated with a reduction in ΔΨ<sub>m</sub>. Application of 50 mM KCl induces a further rise in [Ca<sup>2+</sup>]<sub>c</sub> and profound mitochondrial depolarisation. …”
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19882
How Stable Are 2H-MoS<sub>2</sub> Edges under Hydrogen Evolution Reaction Conditions?
Published 2021“…Hence, we suggest that the 50%S S-edge evolves over time toward a 0%S S-edge, covered by surface OH that will block permanently the active sites.…”
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19883
DataSheet1_Dynamics of trace and rare earth elements during long-term (over 4 years) decomposition in Scots pine and Norway spruce forest stands, Southern Sweden.docx
Published 2023“…The changes in concentration and amount of trace elements resulted in two main types of dynamics: 1) both concentration and amount increased for Fe, Al, Ti, Cu, Mo, V, Zr, Sb, As, Cs, Pb, Th, and U; 2) concentration increased but amount decreased for Ni, Zn, Li, and Sr. …”
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19884
Poly Q aggregates alter the expressions of miR-125b, miR-150, p53, RelA/NFkB and miR-146a.
Published 2011“…(<b>C</b>) Similarly, miR-146a expression (n = 4, p = 0.011), miR-125b expression (n = 2, p = 0.048) and miR-150 expressions (n = 2, p = 0.039) were decreased significantly in ST<i>Hdh<sup>Q7</sup>/Hdh<sup>Q7</sup></i> cells 48 hours post transfection with 83Q DsRed compared to ST<i>Hdh<sup>Q7</sup>/Hdh<sup>Q7</sup></i> cells 48 hours post transfection with empty vector DsRed. miR-17-5p was used as endogenous control to calculate fold change in each case; (<b>D</b>) Immunoblotting with cell extracts prepared from HYPK-GFP transfected ST<i>Hdh<sup>Q7</sup>/Hdh<sup>Q7</sup></i> cells and Hsp70-GFP transfected ST<i>Hdh<sup>Q7</sup>/Hdh<sup>Q7</sup></i> cells showed increase in the expression of HYPK (in panel I probed by anti-HYPK antibody) and Hsp70 (in panel II probed by anti-GFP antibody) respectively compared to those obtained in ST<i>Hdh<sup>Q7</sup>/Hdh<sup>Q7</sup></i> cells transfected with empty vector GFP-C1.…”
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19885
Intron Retention in mRNA Encoding Ancillary Subunit of Insect Voltage-Gated Sodium Channel Modulates Channel Expression, Gating Regulation and Drug Sensitivity
Published 2013“…We investigated the gating and pharmacological properties of the <i>Drosophila</i> Na<sub>v</sub> channel variant (DmNa<sub>v</sub>1-1) co-expressed with DmTEH1, PaTEH1A, PaTEH1B or a truncated mutant PaTEH1Δ(270-280) in <i>Xenopus</i> oocytes. PaTEH1B caused a 2.2-fold current density decrease, concomitant with an equivalent α-subunit incorporation decrease in the plasma membrane, compared to PaTEH1A and PaTEH1Δ(270-280). …”
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19886
DataSheet_1_An anti-sortilin affibody-peptide fusion inhibits sortilin-mediated progranulin degradation.docx
Published 2024“…Treating PGRN-secreting and sortilin-expressing human glioblastoma U-251 cells with the fusion protein increased extracellular PGRN levels up to 2.5-fold, with an EC<sub>50</sub> value of 1.3 nM. …”
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19887
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19888
Total nuclease activity, Dnase1 and Dnase1l1-3 expression in kidneys from BALB/c and (NZBxNZW)F1 mice.
Published 2010“…(<i>A</i>) Kidney lysates (black) or sera (grey), in which total protein was measured, and protein content of the samples normalized using BCA assay (Pierce), were applied onto 1% agarose gels containing calf thymus DNA and ethidium bromide in a CaCl<sub>2</sub>- and MgCl<sub>2</sub>- containing buffer, pH 7.6, and incubated in a humidified chamber at 37°C for 24 hours. …”
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19889
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19890
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19891
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19892
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19893
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19894
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19895
Silencing expression of Foxo1 increases Na<sub>V</sub>1.5 expression.
Published 2012“…<p>Western blots showed decrease of Foxo1 protein by 50 MOI (n = 4) and 100 MOI Adv-Foxo1 RNAi (n = 4) increased Na<sub>V</sub>1.5 protein in HL-1 cells in comparison with 100 MOI Adv-scramble RNAi (n = 4) (A) and this inhibition reached the significant difference (*p<0.05) at 100 MOI Adv-Foxo1-RNAi (C). …”
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19896
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19897
PDGF-BB mediated NIH-3T3 fibroblast chemotaxis is inhibited by MANS pretreatment.
Published 2013“…Data shown represents the average number of cells in 10 high-powered fields from four individual experiments with “a” and “b” denoting a significant decrease in percent (%) wound closure relative to RNS and VC treatment, respectively (p<0.05).…”
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19898
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19899
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19900
Several other FANC factors show a similar influence as FANCA on Alt-EJ and HR.
Published 2015“…*indicates nonspecific band. Also shown is the fold decrease in target mRNA after the respective siRNA treatment, as quantified by qRT-PCR (2<sup>ΔΔCt</sup>, based on normalization to actin and siCTRL treated cells, as in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004943#pgen.1004943.g001" target="_blank">Fig. 1D</a>), for siRNA pools of seven FANC genes (C, E, F, G, M, L, and I). …”