Beta-adrenergic activation induces cardiac collapse by aggravating cardiomyocyte contractile dysfunction in bupivacaine intoxication by Jun Li (6494)

“…The percentage of the sarcomere shortening (bl% peak h), departure velocity (dep v) of sarcomere shortening and time to 50% of the peak speed of myocyte contraction (Tp50) was assessed by a video-based edge-detection system. …”

Ductal branching is dependent upon phenotype heterogeneity within MCF10A in 3-D culture. by Russell Gould (3603524)

“…For compaction and tubular assays, cells were embedded into collagen gels for 72 hrs, and the extent of tubulogenesis was measured at 7 days. (A-D) Within MCF10A, TGF−<i>β</i>2 (10ng/ml) enhanced invasion and contractile properties while, VEGFA (50ng/ml) promoted increased migration. …”

Aβ-induced BACE1 mRNA and protein expressions in activated N2a Swe cells and their reductions by taxifolin and cilostazol. by So Youn Park (141327)

“…Significant decreases in BACE1 protein expression by taxifolin (50 or 100 μM), cilostazol (30 μM), and by 30 μM quercetin (a flavonoid) after 24 hr of treatment. …”

Ubr3 is required for Hh signaling and proper optic vesicle morphogenesis. by Tongchao Li (115391)

table1_Pharmacogenetics–Based Preliminary Algorithm to Predict the Incidence of Infection in Patients Receiving Cytotoxic Chemotherapy for Hematological Malignancies: A Discovery C... by Matias F. Martinez (10281068)

“…</p><p>Pharmacokinetics-related polymorphisms incorporated into the model were CYP3A4 rs2242480C>T and OAT4 rs11231809T>A. Immune/inflammatory response-related polymorphisms were TLR2 rs4696480T>A and IL-6 rs1800796C>G. …”

Declining ELT-2 expression during aging limits lifespan. by Frederick G. Mann (263292)

Data_Sheet_1_Agronomic evaluation of shade tolerance of 16 spring Camelina sativa (L.) Crantz genotypes under different artificial shade levels using a modified membership function... by Yawen Wang (1578763)

“…The mean chlorophyll pigments, including the total chlorophyll and chlorophyll a and b across the 16 genotypes increased as shade level increased, while the chlorophyll fluorescence parameter F_v/F_m, chlorophyll a/b, leaf area, the number of silicles and branches plant⁻¹ decreased as shade level increased. …”

Image_1_Agronomic evaluation of shade tolerance of 16 spring Camelina sativa (L.) Crantz genotypes under different artificial shade levels using a modified membership function.JPEG by Yawen Wang (1578763)

“…The mean chlorophyll pigments, including the total chlorophyll and chlorophyll a and b across the 16 genotypes increased as shade level increased, while the chlorophyll fluorescence parameter F_v/F_m, chlorophyll a/b, leaf area, the number of silicles and branches plant⁻¹ decreased as shade level increased. …”

Differentially expressed genes in <i>erg251Δ/Δ</i> in YPAD compared to wild-type in YPAD. by Xin Zhou (54275)

S2 Fig - by Pierre Ganault (17972799)

Results of t-tests comparing nutrient supply rates (micrograms / 10cm² / burial length) in sterilized versus live soil, in seedling pots. by Katherine E. A. Wood (17325907)

Effect of okadaic acid (OKA) on exflagellation and ookinete formation. by Yonghui Feng (12227596)

Relationships between each parameter relative change and stent wire mesh density. by Shunsuke Masuda (12859231)

Semi-log plot of the number of cities in IT provinces, <i>N</i>_{<i>c</i>,<i>p</i>}; the provinces are ranked by their decreasing “order of importance”, for various years;... by Marcel Ausloos (748325)

Semi-log plot of the number of cities in IT provinces, <i>N</i>_{<i>c</i>,<i>p</i>}; the provinces are ranked according to their decreasing “order of importance”, for vario... by Marcel Ausloos (748325)

Thalamic DBS modulates VPC occurrence over acute and longer time frames. by Michelle J. Redinbaugh (13029044)

The ORF7a protein of SARS-CoV-2 initiates autophagy and limits autophagosome-lysosome fusion via degradation of SNAP29 to promote virus replication by Peili Hou (4737219)

“…In this study, we demonstrate that overexpression of the SARS-CoV-2 ORF7a protein activates LC3-II and leads to the accumulation of autophagosomes in multiple cell lines, while knockdown of the viral <i>ORF7a</i> gene via shRNAs targeting <i>ORF7a</i> sgRNA during SARS-CoV-2 infection decreased autophagy levels. …”

Effect of cell shapes on cluster sizes. by Mrinmoy Mukherjee (5463848)

“…<p>(A) The mean cluster size () of H cells as a function of targeted perimeter of the H cells (<i>p</i>₀) for different values of <i>μ</i> at Γ = 3 calculated at mcs = 50000. is similar for <i>p</i>₀ = [23, 25] and decreases gradually with either an increase or decrease in <i>p</i>₀. …”

Exercise-linked skeletal irisin ameliorates diabetes-associated osteoporosis by inhibiting the oxidative damage-dependent miR-150-FNDC5/pyroptosis axis by Jyotirmaya Behera (11496551)

“…In the present study, we investigated the effect of EX on bone mass and mechanical quality using a diabetic mouse model. The T2DM mouse model was established by a high-fat diet (HFD) with two streptozotocin (STZ) injections (50 mg/kg/body weight) in C57BL/6 female mice. …”

Microphotographs of the thyroid gland of female rats and BMD analysis of follicle depletion. by Matti Viluksela (321291)

“…<p>Decrease of follicle contents is illustrated by comparing samples from controls (A) and 300 mg/kg bw (B). …”