Analysis of SMN levels in different tissues of severe SMA mice. by Francesca Gabanella (34598)

“…(C) Analysis of SMN decrease in the spinal cord of severe SMA mice. Western blot analysis of the indicated serial dilutions (100 equals 50 µg of proteins) of whole tissue extracts from the spinal cord of normal (<i>SMN2</i>^+/+;<i>mSmn</i>^+/+), carrier (<i>SMN2</i>^+/+;<i>mSmn</i>^+/−) and severe SMA (<i>SMN2</i>^+/+;<i>mSmn</i>^−/−) mice at postnatal day 3. …”

Convallatoxin suppresses osteosarcoma cell proliferation, migration, invasion, and enhances osteogenic differentiation by downregulating parathyroid hormone receptor 1 (PTHR1) expr... by Xin Liu (43569)

“…<p>Osteosarcoma (OS) is the most common primary malignant bone tumor in children and adolescents. Convallatoxin, a natural cardiac glycoside, exhibits potent anti-tumor activities. …”

Table_1_Lactose-Induced Chronic Diarrhea Results From Abnormal Luminal Microbial Fermentation and Disorder of Ion Transport in the Colon.XLS by Hong Xue (28736)

“…The concentrations of lactose, galactose and lactic acid of the cecal content were markedly increased (P < 0.01) and SCFA concentration was significantly decreased (P < 0.01). This was associated with depletion of the Lachnospiraceae NK4A136 group and Ruminococcaceae UCG-005 and increased relative abundance of Lactobacillus, escherichia-shigella and megamonas in the cecal microbiota. …”

Changes in Patch Features May Exacerbate or Compensate for the Effect of Habitat Loss on Forest Bird Populations by Ainhoa Magrach (124536)

“…Satellite image analyses revealed that, from 1985 to 2008, forested area decreased by 8.8% and the remaining forest fragments became 16% smaller, 58–73% more isolated and 11–50% more regular. …”

Data Sheet 1_High intensity human activity limits ultra-high altitude soil microbial community dispersal and keystone taxa distribution in southeastern Tibetan Plateau.docx by Wenzu Liu (22364023)

“…Human activities increase the complexity of microbial networks but decrease the stability of soil micro-ecosystems. As elevtation increases, the dispersal limitation of microbial communities decreases (total effect size: bacterial = −0.705, fungal = −0.745). …”

Histological analysis for neurons and myelin. by Svitlana Garbuzova-Davis (81764)

“…Contralateral striatosomes also showed size decreases similar to striatosomes within infarct area. …”

An <i>in-silico</i> analysis to identify structural, functional and regulatory role of SNPs in <i>hMRE11</i> by Bhoomi Tarapara (11977197)

“…<p>Meiotic recombination 11 (<i>MRE11</i>) is a component of the tri-molecular <i>MRE11</i>-RAD50-NBS1 (MRN) complex, which functions as an exonuclease and endonuclease which is involved in identifying, signalling, protecting and repairing double-strand breaks in DNA (DSBs). …”

DataSheet_1_Effects of the neurotoxin β-N-methylamino-L-alanine (BMAA) on the early embryonic development of marine shellfish and fish.docx by Yilei Fu (14287574)

“…A sustained and dose-dependent decrease in heart rate was apparent in marine medaka embryos at 9-days post fertilization following BMAA exposure. …”

Table_1_Assessing Mental Health of Women Living in Karachi During the Covid-19 Pandemic.XLS by Shabnam Shamim Asim (9971105)

“…As the age increased, their scores decreased, with women aged 18–30 having a significantly higher mean depression and anxiety scores compared to women who were above 50. …”

Immunization with <i>Brugia malayi</i> Myosin as Heterologous DNA Prime Protein Boost Induces Protective Immunity against <i>B</i>. <i>malayi</i> Infection in <i>Mastomys coucha</i... by Jyoti Gupta (825079)

Application of TREM2-Transduced Myeloid Cells Reduced Axonal and Myelin Injury by Kazuya Takahashi (69459)

“…<div><p>(A) Reduced spinal cord axonal injury and decreased demyelination after cell therapy by TREM2-transduced myeloid cells. …”

Positive feedback on osteoclast formation is critical for obtaining oscillations with increasing amplitude. by Timur Akchurin (377722)

“…<p>A) Parametric portrait of the system in the space of parameters <i>k</i>₉<i>k</i>₁₀; <i>k</i>₆–<i>k</i>₈; <i>k</i>₁₁. …”

Normal morphology of doublecortin-positive neurons after environmental enrichment in APP_Sw,Ind mice. by Jorge Valero (230721)

“…(C) Number of dendritic endings into the area delimited by concentric circles at increasing radius (50 µm). Decreased number of neuronal dendritic endings at 150 µm from the soma in APP_Sw,Ind mice is reversed by EE. …”

Fig 3 - by Katharina Rump (2224759)

“…<p>Methylation of <i>BCHE</i> in neuronal SH-SY5Y and U343 cells after midazolam incubation A) <i>BCHE</i> intron 2 methylation reduced after midazolam (50 μg/ml) exposure of SH-SY5Y cells (n = 3; p = 0.01) analyzed by methylation specific PCR. …”

IGF2 knockdown alters the cellular response to Taxol. by Jurriaan Brouwer-Visser (578686)

“…<p>Taxol-induced G2/M arrest. (A) HEY-T30 cells were treated for 16 hours with the indicated concentrations of Taxol, and DNA content analyzed by flow cytometry. …”

Kinematic Profiles of Mudskipper Pectoral Fin versus Salamander Hindlimb by Zachary Quigley (11422969)

“…Individual trials were pooled for each species (N = 50 trials for P. barbarus pectoral fins and N = 46 for A. tigrinum hindlimbs, which had two trials removed due to extreme outliers) and profiles were plotted as mean ± s.e.m. for each percent of stance. …”

Supplementary Material for: Identification of risk factors associated with metabolic dysfunction-associated steatotic liver disease in psoriatic patients by Küçük K. (20178678)

“…There was no significant difference between the mean age of both patient groups (50.4 vs 47.3 years, p=0.26). …”

The RBPJ AOS variants show dysregulated Notch target gene expression when compared to WT RBPJ. by Ellen K. Gagliani (11478756)

“…Cells were additionally transfected with increasing concentrations (50, 150 & 250 ng) of either WT, NBM (F261A/V263A/R422E/E425R/E398R), KRS (K195E/R218H/S221D), NBM/KRS, or K195E Rbpj constructs in panels <b><i>ii-iv</i></b>. …”

Wnk signals through Fray to regulate glial potassium flux. by Lorenzo Lones (14374536)

Data Sheet 3_Cepharanthine may inhibit the proliferation of prostate cells by blocking the EGFR/PI3K/AKT signaling pathway: comprehensive network analysis, molecular docking, and e... by Yin Huang (179237)

“…In vitro experiments showed that CEP inhibited WPMY-1 (IC₅₀ = 6.396 μM) and BPH-1 (IC₅₀ = 2.355 μM) proliferation in a dose-dependent manner. …”