Table1_Effectiveness of early heparin therapy on outcomes in critically ill patients with sepsis-induced coagulopathy.docx by Jia-Jia Huang (243641)

“…Further analysis showed that treatment with 6,250–13750 IU/day of unfractionated heparin associated with a decreased risk of intensive care unit mortality. …”

Table 1_Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy.docx by Chao Lv (335727)

“…Ultra-high-performance liquid chromatography-quadrupole orbitrap mass spectrometry (UHPLC-QTOF-MS) was used to identify the metabolites in TFA. MAFLD mice induced by a high-fat diet were treated with TFA at doses of 50 and 100 mg/kg. …”

Table 2_Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy.docx by Chao Lv (335727)

“…Ultra-high-performance liquid chromatography-quadrupole orbitrap mass spectrometry (UHPLC-QTOF-MS) was used to identify the metabolites in TFA. MAFLD mice induced by a high-fat diet were treated with TFA at doses of 50 and 100 mg/kg. …”

Distinct Roles for the vBcl-2-mediated Inhibition of Autophagy and Apoptosis in γHV68 Chronic Infections In Vivo. by Xiaofei E (82852)

“…<p>Splenic infectious centers measured at 12 dpi (A, left), 14 dpi (B, left), 21 dpi (C, left), 28 dpi (D, up), 35 dpi (E, up), or 42 dpi (F, up) and viral genome load measured by real-time PCR at 12 dpi (A, right), 14 dpi (B, right), 21 dpi (C, right), 28 dpi (D, down), 35 dpi (E, down), or 42 dpi (F, down), in the BALB/c mice intranasally infected with the WT or recombinant γHV68 mutants, as indicated (Mean±SEM of five mice per group/time point/experiment). …”

DataSheet_1_Temperature and elevated CO2 alter soybean seed yield and quality, exhibiting transgenerational effects on seedling emergence and vigor.docx by Naflath Thenveettil (19262185)

“…When the growing temperature increased from optimum to high, the seed oleic acids increased (63%), while linoleic and linolenic acids decreased (- 28% and - 43%, respectively). Significant temperature and CO₂ effects were observed in progenies with the highest maximum seedling emergence (80%), lesser time to 50% emergence (5.5 days), and higher seedling vigor from parents grown at low-temperature treatment under eCO₂.…”

<i>Fgf20</i> is necessary for formation of the lateral compartment of the organ of Corti. by Sung-Ho Huh (191072)

“…Total numbers of hair cells were decreased by 50% in <i>Fgf20^βGal/βGal</i> cochlea. …”

Image_1_BML-111 Reduces Neuroinflammation and Cognitive Impairment in Mice With Sepsis via the SIRT1/NF-κB Signaling Pathway.TIF by Shangwen Pan (5648291)

“…Boc-2 (50 μg/kg) was administered intracerebroventricularly 30 min before CLP, and EX527 (10 μg) was administered every 2 days for a total of three times before CLP, also intracerebroventricularly. …”

Methodology flow chart. by Sidra Aman Rana (14167473)

“…<div><p>Domestic water availability is intricately linked with a growing population, urbanization, and associated land use/land cover change (LULCC). …”

eIF3f regulated rRNA stability through hnRNP K. by Fushi Wen (175725)

“…(D) Silencing of hnRNP K decreased rRNA. Predesigned hnRNP K siRNA (50 nM, Eurogentec) was transfected into MiaPaCa-2 cells using Lipofectamine. rRNA and hnRNP K mRNA fold changes compared to control RNAi cells were assessed by real time RT-PCR after 48 hours. …”

Fig 10 - by Narasimha M. Beeraka (12189587)

“…BT-474 cells with cisplatin/oxaliplatin treatment: expression of FN3K, Nrf2, and Keap1 was not completely declined with cisplatin but NQO1, and HO-1 expression was mitigated at higher concentrations; interestingly, oxaliplatin downregulated the expression of FN3K and Nrf2 consequently mitigated expression of antioxidant proteins such as NQO1 and HO-1. 1-deoxy-1-morpholinofructose (DMF) (dissolved in 50% ethanol), a competitive inhibitor of FN3K, was used as a positive control which could only inhibit ∼10% of total FN3K activity but the FN3K expression was not decreased upon DMF treatment [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0283705#pone.0283705.ref012" target="_blank">12</a>]. …”

Luminescent Hydrido-Carbonyl Clusters of Rhenium Containing Bridging 1,2-Diazine Ligands by Monica Panigati (1734016)

“…In the case of <b>4a</b>, a blue shift and an increase of the emission intensity were observed upon decreasing the solvent polarity.…”

Model sensitivity analysis to parameters: <i>k</i>_<i>τ</i>, <i>τ</i>_<i>max</i>, <i>F</i>_<i>p</i>, <i>F</i>_<i>c</i>, <i>K</i><sub><i>r</i... by Dharsan K. Soundarrajan (11632145)

“…<i>e</i>., 50% of a BV of 1.5 μM would simulate a value of 0.75 μM). …”

Chromatin relaxation affects spliceosome recruitment to nascent RNA and binding of splicing factors to ncRNAs. by Ignacio E. Schor (120406)

“…S5</a>). Orange boxes mark regions with peaks appearing at 2 h TSA and not further increasing, or even decreasing, at 6 h (MALAT1 peaks). …”

Data Sheet 1_OvaRePred (HerTempo): an enhanced ovarian aging clock for personalized reserve assessment, endocrine age modeling, and predicting reproductive milestones across the fe... by Huiyu Xu (12255545)

“…A two-parameter logistic curve allowed translation of ovarian reserve scores into an “endocrine age” and enabled individualized prediction of future milestones, such as diminished reserve with ovarian score of 50 and perimenopause, the lowest ovarian reserve score in our ART population. …”

Gene activation and global RNA synthesis by NGF. by Yu-Wei Lee (432337)

“…<p>(<b>A</b>)PC12 cells were incubated with NGF (50 ng/ml) or without NGF for 4 hours. mRNA levels were measured using RT-qPCR relative to the house keeping gene <i>cyclophilin A</i> mRNA. …”

<i>ab</i> cooperates with impaired Hippo pathway signalling to drive tumour overgrowth. by Nezaket Turkel (434914)

“…F-actin for cell morphology is in red. GFP (panels A–H), Elav (panels A′–D′), Dac (panels E′F′), Eya (panels G′H′), and merges (panels A″–H″). …”

Image 4_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.tif by Tong Luo (458639)

“…Introduction<p>Acute lung injury (ALI) is a life-threatening respiratory disorder characterized by excessive inflammation and oxidative stress, with no specific pharmacological therapy currently available. …”

HAS inhibition in HepR21 leads to ROS surge, decline in HA level and upregulated MAP-LC3 levels. by Paramita Saha (473954)

“…<p>[A] <b><i>Inhibition of HA synthesis led to increased generation of ROS</i></b><b>—</b> HepR21 cells subjected to treatment with different concentrations of HA synthetase inhibitor, 4-MU and untreated cells were assayed for ROS. 4-MU treatment resulted in excess generation of ROS as a function of time and concentration. …”

Supplementary file 1_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.docx by Tong Luo (458639)

“…Introduction<p>Acute lung injury (ALI) is a life-threatening respiratory disorder characterized by excessive inflammation and oxidative stress, with no specific pharmacological therapy currently available. …”

DataSheet1_Reduce the application of phosphorus fertilizer in peanut fields and improve its efficiency by using iron modified biochar to adsorb phosphorus recovery products.docx by Junxiao Zhang (421908)

“…After the fifth desorption and recycling process, the adsorption capacity of the biochar decreased to 24%. The peanut yield in the FeB-P1 treatment was 50.8% higher than that in the FeBP-P2 treatment. …”