Macrophage migration inhibitory factor antagonist (p425) ameliorates kidney histopathological and functional changes in diabetic rats by Jamal Khalilpour (6302258)

“…The aim of the present study was to investigate the renal effects of MIF inhibition in a diabetic experimental model. Methods: Eighteen male Wistar rats (230 ± 20 g) were divided into three groups: 1) control, 2) diabetic (STZ, 50 mg/kg, dissolved in saline, ip), 3) diabetic + MIF antagonist (p425, 1 mg/kg per day, ip, on the 21th day, for 21 consecutive days). …”

Uniform downscaling of postsynaptic AMPA receptors across the dendritic tree in primary hippocampal cultures. by Mathieu Letellier (6803699)

“…(B) Representative EPSC trace evoked by a pair of brief depolarizations (+100 mV, 50-ms interval) of the presynaptic neuron. …”

Data_Sheet_1_Epigenetic Effects Promoted by Neonicotinoid Thiacloprid Exposure.pdf by Colin Hartman (11080926)

“…In addition, we found that exposure to thia results in a decrease in H3K9me3 levels in spermatocytes. …”

Overview of the comparative analysis of deconvolution model performances using synthetic spatial data in four different scenarios and six different mixture percentages. by Nuray Sogunmez Erdogan (21533872)

“…Tested deconvolution algorithms are DWLS, RCTD, S-DWLS, SPOTlight, Stereoscope, and WISpR. <b>A</b>, A mean Root Mean Squared Error (RMSE) assessment of predictive performances of six methods’ performances. …”

Evaluation of the immunomodulatory activity of thalidomide on tumor-associated macrophages in the 4T1 murine metastatic breast cancer model by D.C. Reis (4770336)

“…<div><p>ABSTRACT The present work evaluated the immunomodulatory effect of thalidomide (Thal) at different doses on tumor-associated macrophages (TAMs) using a mouse model of human breast cancer. Mice were inoculated with 4T1 cells in the left flank and treated with Thal once a day at concentrations of 50, 100, and 150mg/kg body weight from the 5th day until the 28th day of tumor inoculation. …”

Do psychosocial factors modify the negative association between disability and life satisfaction in old age? by Thomas Puvill (726017)

“…</p><p>Setting</p><p>66,561 community-dwelling Survey of Health, Ageing, and Retirement in Europe (SHARE) participants aged 50–106 with a mean age of 67.8 ± 9.9 (SD) years from 17 European countries and Israel.…”

Predictive coding of sensory inputs and emergent oscillations. by Kwangjun Lee (22226994)

“…As PE decreases, the color of animation becomes lighter and prediction becomes clearer. …”

Gas exchanges and production of watermelon plant under salinity management and nitrogen fertilization by Saulo Soares da Silva (7291103)

“…The experiment was conducted in a randomized block design, arranged in a 6 x 2 factorial scheme, with five replicates, corresponding to six irrigation strategies with saline water applied at different phenological stages of the crop (control - irrigation with low-salinity water throughout the entire crop cycle, and salt stress at the vegetative stage, vegetative/flowering stage, flowering, fruiting and fruit maturation) and two nitrogen rates (50 % and 100 %, equivalent to 50 mg and 100 mg of N kg-1 of soil). …”

Image_2_Light intensity changes and UVB radiation affect peridinin content and antioxidant activity in the Cassiopea andromeda holobiont.jpeg by Holger Kühnhold (6499133)

“…</p>Materials and Methods<p>Indoor bred C. andromeda specimens were exposed to five different PAR intensities (50, 100, 200, 400 and 800 µmol photons m⁻² s⁻¹) and a combined treatment of narrow-band UVB (λ = 285 ± 10 nm) radiation and intermediate (200 µmol photons m⁻² s⁻¹) PAR intensity over a period of four weeks. …”

Image_1_Light intensity changes and UVB radiation affect peridinin content and antioxidant activity in the Cassiopea andromeda holobiont.jpeg by Holger Kühnhold (6499133)

“…</p>Materials and Methods<p>Indoor bred C. andromeda specimens were exposed to five different PAR intensities (50, 100, 200, 400 and 800 µmol photons m⁻² s⁻¹) and a combined treatment of narrow-band UVB (λ = 285 ± 10 nm) radiation and intermediate (200 µmol photons m⁻² s⁻¹) PAR intensity over a period of four weeks. …”

DEVELOPMENT OF AN ANALYTICAL METHOD FOR THE DETERMINATION OF LEAD BASED ON LOCAL SURFACE PLASMON RESONANCE OF SILVER NANOPARTICLES by Hamed Azimi (1521268)

Molecular Hybridization-Inspired Optimization of Diarylbenzopyrimidines as HIV‑1 Nonnucleoside Reverse Transcriptase Inhibitors with Improved Activity against K103N and E138K Mutan... by Sheng Han (419184)

“…The antiviral activity of this compound was much higher than those of ETR and EFV against the WT, E138K, and K103N variants (EC₅₀ = 3.4, 4.3, and 3.6 nM, respectively), and the cytotoxicity was decreased while the selectivity index (SI) was increased. …”

Cell parameter sensitivity for switch cell islets. by Janita P. Hogan (10573758)

DataSheet_1_Hair cortisol and changes in cortisol dynamics in chronic kidney disease.pdf by Laura Boswell (12123132)

“…Reduced cortisol suppression after 1-mg dexamethasone suppression (DST) (p < 0.001), a higher noon (12:00 h pm) salivary cortisol (p = 0.042), and salivary cortisol AUC (p = 0.008) were seen in CKD. 24-h urinary-free cortisol (24-h UFC) decreased in CKD stages III–IV compared with I–II (p < 0.001); higher midnight salivary cortisol (p = 0.015) and lower suppressibility after 1-mg DST were observed with declining kidney function (p < 0.001). …”

DataSheet_1_Hair cortisol and changes in cortisol dynamics in chronic kidney disease.pdf by Laura Boswell (12123132)

“…Reduced cortisol suppression after 1-mg dexamethasone suppression (DST) (p < 0.001), a higher noon (12:00 h pm) salivary cortisol (p = 0.042), and salivary cortisol AUC (p = 0.008) were seen in CKD. 24-h urinary-free cortisol (24-h UFC) decreased in CKD stages III–IV compared with I–II (p < 0.001); higher midnight salivary cortisol (p = 0.015) and lower suppressibility after 1-mg DST were observed with declining kidney function (p < 0.001). …”

Mapping of serum neutralizing activity in high titer, protected RM using BG505 Env PV mutants. by Tysheena P. Charles (3385586)

“…The second row represents whether a log fold decrease or increase in ID₅₀ titer is expected. …”

Supplementary Table S1: Sequences of additionally tested antisense oligonucleotides by Alexandra Dainis (8351694)

“…Stadhouders et al. reported that A-A, A-G, C-C, G-G, G-A binding mismatches showed the greatest decrease in off target binding in a real-time PCR assay, so we designed our mismatch ASOs to contain these mismatch pairs when possible <a href="https://paperpile.com/c/bTaOUO/sLzRQ">[5]</a>. …”

Analgesic and antiinflammatory activities of the essential oil from Artemisia sieberi Besser by Elahe Pishgahzadeh (8185611)

“…The dose of 1 mg/kg of the oil also exhibited a central analgesic effect as evidenced by a significant increase in reaction time at several time points after 15 min treatment in the hot plate method. …”

Effect of Cinnamomum verum leaf essential oil on virulence factors of Candida species and determination of the in-vivo toxicity with Galleria mellonella model by Gayan Kanchana Wijesinghe (10377462)

“…MBIC50 for forming biofilms were ≤ 0.35 mg/mL. 1.0 mg/mL prevent biofilm progression of Candida. …”

Table1_Targeted Plasmalogen Supplementation: Effects on Blood Plasmalogens, Oxidative Stress Biomarkers, Cognition, and Mobility in Cognitively Impaired Persons.DOCX by Dayan B. Goodenowe (13004757)

“…Administration of 1-O-alkyl-2-acylglycerol (AAG) plasmalogen precursors containing DHA at the sn-2 position dose-dependently increase blood DHA plasmalogens and are neuroprotective in animal models of neurodegeneration at doses between 10 and 50 mg/kg. We conducted an investigational clinical trial in 22 cognitively impaired persons to evaluate the effects of an escalating oral dosing regimen of DHA-AAG from 900 to 3,600 mg/day over a 4-month period on blood serum plasmalogen and non-plasmalogen phospholipids and oxidative stress biomarkers. …”