DataSheet_2_A cyclic peptide-based PROTAC induces intracellular degradation of palmitoyltransferase and potently decreases PD-L1 expression in human cervical cancer cells.docx by Yu-Ying Shi (15975992)

“…Introduction<p>Our previous research has found that degradation of palmitoyltransferase in tumor cells using a linear peptide PROTAC leads to a significant decrease in PD-L1 expression in tumors. …”

Knockdown of MRN complex decreases HBV cccDNA level. by Kaitao Zhao (3617825)

Knockdown of MRN complex decreases HBV cccDNA level. by Kaitao Zhao (3617825)

Cardiac-specific p38γ/δ^act overexpression decreases cardiac glycogen storage and lipid accumulation. by Ayelén M. Santamans (5487941)

Fig 1 - by Dalia Zaafar (6693017)

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Fig 3 - by Dalia Zaafar (6693017)

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Fig 5 - by Dalia Zaafar (6693017)

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Photomicrographs representing caspase-3 immunoreactivity in the sarcoplasm of cardiomyocytes of mice of different groups. by Dalia Zaafar (6693017)

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Fig 4 - by Dalia Zaafar (6693017)

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Simulated effects of increased pCREB combined with decreased pCaMKIIα on bistability. by Yili Zhang (540283)

“…<p>(A1) Modification of model. Increased basal phosphorylation of CREB <i>k</i>_{<i>basalp_creb</i>}, concurrent with decreased basal phosphorylation of CaMKIIα <i>k</i>_{<i>basalp_CaMKII</i>}, in the absence of the effects of MeCP2/HDAC2/Sin3a (red) ([<i>E</i>_<i>comp</i>] = 0; [<i>E</i>_<i>MeCP2</i>] = 0). …”

The decrease or inhibition of Hsp90 induced REST degradation. by Raúl Orozco-Díaz (7067624)

“…(D) The level of REST dramatically reduced in differentiated SH-SY5Y cells treated with GA (1 μM) or PU-H71 (50 nM) at 24 h. (E) The REST level decreased by GA more than 50% and (F) PU-H71 more than 80%, respectively. …”

HPD 1466 decreases empty capsid accumulation in cells replicating HBV. by Daniel P. Bradley (10306893)

Lymphocytes decreased in mouse pneumonia model. by Qi Xu (134661)

Proteasomal activity decreases with ApoE4 expression. by Nathan R. Zuniga (20422428)

<i>Aspergillus flavus</i> mRNA expression (a) <i>aflD</i> and (c) <i>aflR</i> and phylogenetic analysis of (b) <i>aflD</i> and (d) <i>aflR</i> after exposure to 50 mg/mL of <i>U. e... by Martha Cebile Jobe (21175426)

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MBIC50 and MBEC50 values (µg/mL) of synthesized 1,2,3,5-tetrazine derivatives against bacteria pathogen strains. by Jean Paul Dzoyem (6424445)

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Decreased number of cones and retinal ganglion cells in Oc-deficient retina. by Michaela Kreplova (9239560)

<i>Kdm6a</i> conditional KO mice have decreased repopulating potential in serial competitive transplantation assays. by Ling Tian (107492)

“…Whole BM cells were harvested from all cohorts of young <i>Kdm6a</i> conditional KO mice (CD45.2) and mixed with WT competitor marrow (CD45.1 x CD45.2) in a 1:1 ratio, which was then transplanted into lethally-irradiated primary recipient mice (CD45.1). …”

Effect of control or Notch3 ASOs administered subcutaneously to C57BL/6 wild type mice on <i>Notch3</i> mRNA. by Ernesto Canalis (516050)

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Growth of cell monolayers and 3D spheroids under different concentrations of HIF inhibitor YC-1 in growth media. by Sreerupa Sarkar (9628788)