The Non-Catalytic Domains of <i>Drosophila</i> Katanin Regulate Its Abundance and Microtubule-Disassembly Activity by Kyle D. Grode (725568)

“…<div><p>Microtubule severing is a biochemical reaction that generates an internal break in a microtubule and regulation of microtubule severing is critical for cellular processes such as ciliogenesis, morphogenesis, and meiosis and mitosis. …”

Hemodiafiltration Decreases Serum Levels of Inflammatory Mediators in Severe Leptospirosis: A Prospective Study by Sérgio Aparecido Cleto (3143949)

VCP inhibition induces accumulation of ubiquitinated-proteins and decreases NFκB-expression. by Kyla Walworth (3150936)

“…The increase in ubiquitinated-protein accumulation in soluble protein-fraction suggests that the DDN^DBeQ treatment alters VCP-function resulting in proteostasis-inhibition and ER-accumulation of these proteins. We also see a significant decrease in expression of tumor-mediator, NFκB in DDN/DDN^DBeQ treated samples as compared to the control-vehicle, although DDN^DBeQ was most effective as anticipated. …”

Mitochondrial protein acetylation correlates with a decrease in sirtuin 3 levels. by Mercedes García-Roche (6459200)

The distributions of the end-simulation adolescence-limited proportion when (a) <i>k</i> is increased or decreased by 50%, (b) <i>c</i> is increased or decreased by 50%, (c) <i>γ</i> is increased or decreased by 50%, and (d) Δ<i>e</i> is increased or decreased by 50%, compared against the benchmark distribution <i>F</i>(<b>p</b>₀) for the parameters shown in Table 1. by Jia Ning Leaw (752775)

Proliferative tissue degeneration is accompanied by a sustained decrease in proliferation, acute apoptotic responses, and progressive accumulation of DDR foci. by Catarina M. Henriques (102294)

“…Proliferative tissues such as A) testes, B) head kidney and C) gut sections show sustained significant decrease in proliferation in <i>tert^−/−</i> as compared to <i>tert^+/+</i> siblings (panels b, d and e) (p<0.001) and an acute apoptotic response at 3 months of age (p<0.001), which clears by c. 12 months (panels g, i and j). …”

Downregulation of DOM decreases the abundance of PER and TIM. by Zhenxing Liu (399809)

“…Downregulation of DOM decreased PER levels at CT1-5 and CT17-21. (Scale bar: 50 um.) …”

Table_1_Gomisin A Suppresses Colorectal Lung Metastasis by Inducing AMPK/p38-Mediated Apoptosis and Decreasing Metastatic Abilities of Colorectal Cancer Cells.DOC by Ji-Ye Kee (4011965)

“…Both oral and intraperitoneal administration of G.A (50 mg/kg) inhibited lung metastasis of CT26 cells. …”

Both with somatic and with dendritic stimulation, pyramidal cell burst firing decreases as the apical dendrite becomes shorter. by Ronald A. J. van Elburg (80591)

Both with somatic and with dendritic stimulation, pyramidal cell burst firing decreases as the apical dendrite becomes shorter. by Ronald A. J. van Elburg (80591)

Relationship between Differential Hepatic microRNA Expression and Decreased Hepatic Cytochrome P450 3A Activity in Cirrhosis by Raj Vuppalanchi (458660)

“…In this study, we examined if certain microRNAs (miRNA) are associated with decreased hepatic CYP3A activity in cirrhosis.…”

BIC of models tested throughout model building. by Guillaume Lingas (9955528)

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Pharmacokinetic models and concentrations predictions of treatments considered. by Guillaume Lingas (9955528)

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Mutagenesis model simulations. by Guillaume Lingas (9955528)

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Decreased levels of ubiquitinated proteins in U87MG cells that express PTEN. by Rajaa Errafiy (497050)

Inhibition of Nuclear Factor-Kappa B Activation Decreases Survival of <i>Mycobacterium tuberculosis</i> in Human Macrophages by Xiyuan Bai (407197)

“…Inhibition of the executioner protease caspase-3 or of the autophagic pathway significantly abrogated the effects of BAY. We conclude that NFκB inhibition decreases viability of intracellular <i>MTB</i> in human macrophages via induction of apoptosis and autophagy.…”

Multinomial logistic model of the effects of a cluster of phenolic compounds on host and parasitoid survival across development among larvae that survived to at least 50 mg. by Noah H. Rose (703745)

BCG-AS−Ndk has decreased intracellular survival due to increased phagolysosome fusion. by Jim Sun (367834)

ROS and superoxide decrease in the dormant form of mycobacteria. by Amar Yeware (7115063)

The introduction of mutualisms into assembled communities increases their connectance and complexity while decreasing their richness. by Gui Araujo (22170819)

“…(C) Mutualism also promotes an increase in network connectance when introduced into assembled communities, while stopping mutualistic interactions from entering an assembled system slowly decreases it. (D) As a result, the introduction of mutualistic interactions promotes a growth in complexity in communities where it was once established as low, while stopping the introduction of further mutualistic interactions causes a slight decrease in complexity. …”