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241
Juvenile demyelination leads to a substantial decrease in potassium currents in PV interneurons of the PFC.
Published 2025“…Scale: 500 pA, 100 ms. <b>B</b>. I–V curves showing a significant decrease in Kv amplitude in PV interneurons from mice that underwent juvenile demyelination. …”
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Low concentrations of siRNA TMPRSS2-ERG III and IV impair TMPRSS2-ERG oncogene and oncoprotein levels but not cell viability.
Published 2015“…One hundred percent cell viability corresponds to the number of living cells incubated with transfecting agent only. Results are the mean ± SD of two independent experiments containing 8 replicates for each condition. * = <i>p</i><0.05, ** = <i>p</i><0.01, *** = <i>p</i><0.001, significant decrease compared to untreated cells (TA) or to siRNA Control (Kruskal & Wallis followed by Tukey and Dunnet test).…”
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246
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Receptor specific silencing decreases NGF induced apoptosis.
Published 2013“…A 37.5%-decrease (*) and a 50%-decrease (**) of apoptotic signal were detected respectively in p75<sup>NTR</sup>-siRNA and p75<sup>NTR</sup>/trkA<sup>NGFR</sup>-siRNA (p<.05).…”
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Astrocytic AQP4 is decreased in aged cortical astrocytes.
Published 2015“…<p>(A) AQP4 immunoreactivity (blue) and protein levels (B) are significantly decreased in the aged cortex. …”
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252
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Antineoplastic Effects of siRNA against TMPRSS2-ERG Junction Oncogene in Prostate Cancer
Published 2015“…The siRNA against TMPRSS2-ERG fusion variant IV showed the highest anti-proliferative effects: Significantly decreased cell viability, increased cleaved caspase-3 and inhibited a cluster of anti-apoptotic proteins. …”
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254
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Proteasome activity was decreased in the <i>myc-rpt6-S119A</i> mutant.
Published 2017“…The mean ± SEM rate of Suc-LLVY-AMC cleavage is decreased in the <i>myc-rpt6-S119A</i> mutant compared to the WT and <i>myc-rpt6-S119D</i> strains. …”
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256
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A Functional 12T-Insertion Polymorphism in the <i>ATP1A1</i> Promoter Confers Decreased Susceptibility to Hypertension in a Male Sardinian Population
Published 2015“…The <i>ATP1A1</i> promoter containing the 12T-insertion exhibited decreased transcriptional activity in in vitro reporter-assay systems, indicating decreased α1Na,K-ATPase expression with the 12T-insertion, compared with the 12T-deletion <i>ATP1A1</i> promoter. …”
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Data_Sheet_1_Perceptual Priming Can Increase or Decrease With Aging.PDF
Published 2020“…<p>A decline in declarative or explicit memory has been extensively characterized in cognitive aging and is a hallmark of cognitive impairments. …”