Mitotic Checkpoint Kinase Mps1 Has a Role in Normal Physiology which Impacts Clinical Utility by Ricardo Martinez (5665279)

“…Using an isogenic cellular model system, PF-7006 is shown to be selectively cytotoxic to Rb1-deficient cells relative to Rb1-competent cells (also a measure of kinase selectivity). Human bone marrow cells pretreated with palbociclib have decreased PF-7006-dependent apoptosis relative to cells without palbociclib pretreatment. …”

Antiaromaticity-Promoted Activation of Dihydrogen with Borole Fused Cyclooctatetraene Frustrated Lewis Pairs: A Density Functional Theory Study by Danling Zhuang (9109239)

“…However, combining these two concepts together for H₂ activation is less developed. Herein, we report a density functional theory study on antiaromaticity-promoted H₂ splitting. …”

Inhibition of Enterovirus 71 (EV-71) Infections by a Novel Antiviral Peptide Derived from EV-71 Capsid Protein VP1 by Chee Wah Tan (167218)

“…Substitutions of arginine and lysine residues with alanine in the SP40 peptide at positions R3A, R4A, K5A and R13A were found to significantly decrease antiviral activities, implying the importance of positively charged amino acids for the antiviral activities. …”

Data_Sheet_1_Systematic Assessment of COVID-19 Pandemic in Bangladesh: Effectiveness of Preparedness in the First Wave.docx by Priom Saha (11590057)

Schematic illustration of the complex locus on chromosome 2 associated with leaf molybdenum concentrations. by Simon K. G. Forsberg (673429)

“…A fourth independent GWA association (SNP₂) was also detected upstream of vBLOCK. The direction of the effects for the minor alleles at the significantly associated loci (<i>SNP1</i>^<i>+</i>, <i>SNP2</i>^<i>+</i>, <i>DEL</i>^<i>53</i> and <i>DUP</i>^<i>326</i>) relative to that of the major, reference allele are illustrated with + (increased) and—(decreased), respectively. …”

RNA-seq analysis of PAX9-depleted MCF10A cells relative to siNT control. by Katherine I. Farley-Barnes (9258036)

“…For the second column, a 1 denotes that the mRNA had decreased expression (fold change ≤ - 2) in the RNA-seq dataset, while a 0 indicates denotes that the mRNA had increased expression (fold change ≥ - 2) in the RNA-seq dataset. …”

Proteomic analysis of the response of <i>Trichinella spiralis</i> muscle larvae to exogenous nitric oxide by Xiaoli Wang (46677)

“…<i>spiralis</i>. Herein, we applied label-free analysis to investigate the effect of sodium nitroprusside (SNP, a NO donor compound) on the proteome of <i>T</i>. …”

Table_6_Effect of high-dose Spirulina supplementation on hospitalized adults with COVID-19: a randomized controlled trial.docx by Mohammad Reza Aghasadeghi (9524778)

“…This study aimed to evaluate the efficacy and safety of high-dose Spirulina platensis for SARS-CoV-2 infection.</p>Study Design<p>We conducted a randomized, controlled, open-label trial involving 189 patients with COVID-19 who were randomly assigned in a 1:1 ratio to an experimental group that received 15.2g of Spirulina supplement plus standard treatment (44 non-intensive care unit (non-ICU) and 47 ICU), or to a control group that received standard treatment alone (46 non-ICU and 52 ICU). …”

Table_2_Effect of high-dose Spirulina supplementation on hospitalized adults with COVID-19: a randomized controlled trial.docx by Mohammad Reza Aghasadeghi (9524778)

“…This study aimed to evaluate the efficacy and safety of high-dose Spirulina platensis for SARS-CoV-2 infection.</p>Study Design<p>We conducted a randomized, controlled, open-label trial involving 189 patients with COVID-19 who were randomly assigned in a 1:1 ratio to an experimental group that received 15.2g of Spirulina supplement plus standard treatment (44 non-intensive care unit (non-ICU) and 47 ICU), or to a control group that received standard treatment alone (46 non-ICU and 52 ICU). …”

Table_3_Characteristics of full compensation and its association with total astigmatism: A cross-sectional study.DOCX by Ziyun Wu (413514)

“…Astigmatism was defined as a cylinder that was better than or equal to 0.75 diopters (D). …”

Table_2_Characteristics of full compensation and its association with total astigmatism: A cross-sectional study.DOCX by Ziyun Wu (413514)

“…Astigmatism was defined as a cylinder that was better than or equal to 0.75 diopters (D). …”

Conventional vs. Tablet Computer-Based Patient Education following Lung Transplantation – A Randomized Controlled Trial by Hendrik Suhling (532255)

“…term=gottlieb+tablet+pc+education&rank=1</a>.</p></div>…”

Table_1_Characteristics of full compensation and its association with total astigmatism: A cross-sectional study.DOCX by Ziyun Wu (413514)

“…Astigmatism was defined as a cylinder that was better than or equal to 0.75 diopters (D). …”

The effect of 3-month finasteride challenge on biomarkers for predicting cancer outcome on biopsy: Results of a randomized trial by Javier Hernandez (242120)

“…Relative to baseline, the 90-day PCA3 and PSA decreased in the finasteride group by 25% and 50%, respectively (both p<0.001). …”

Table_3_A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation.xlsx by Ermeng Xiong (11176635)

“…Hdac1 knock-out led to strongly perturbed protein expression of antagonistic transcription factors that govern plasma cell versus B cell identity (by decreasing IRF4 and BLIMP1 and increasing BACH2 and PAX5).…”

Evaluation of a Dengue NS1 Antigen Detection Assay Sensitivity and Specificity for the Diagnosis of Acute Dengue Virus Infection by Laura L. Hermann (638244)

“…We found significant variation in the sensitivity of the InBios NS1 ELISA kit depending on the serotype of the dengue virus and also found decreasing sensitivity the longer after the onset of illness, showing 100% sensitivity early during illness, but dropping below 50% by Day 7.…”

Table_2_A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation.xlsx by Ermeng Xiong (11176635)

“…Hdac1 knock-out led to strongly perturbed protein expression of antagonistic transcription factors that govern plasma cell versus B cell identity (by decreasing IRF4 and BLIMP1 and increasing BACH2 and PAX5).…”

Table_4_A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation.xlsx by Ermeng Xiong (11176635)

“…Hdac1 knock-out led to strongly perturbed protein expression of antagonistic transcription factors that govern plasma cell versus B cell identity (by decreasing IRF4 and BLIMP1 and increasing BACH2 and PAX5).…”

Table_1_A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation.xlsx by Ermeng Xiong (11176635)

“…Hdac1 knock-out led to strongly perturbed protein expression of antagonistic transcription factors that govern plasma cell versus B cell identity (by decreasing IRF4 and BLIMP1 and increasing BACH2 and PAX5).…”

Tetracaine induces apoptosis through a mitochondrion-dependent pathway in human corneal stromal cells <i>in vitro</i> by Zhan Song (5445803)