GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age. by Nicole K. Polinski (10947787)

“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”

Means for STEM competence for pre- and post-test. by Esther Kim (2996622)

“…After the Challenge, participants increased in awareness of global issues, and engagement with others, but also showed a small but significant decrease in respect for people from other cultural backgrounds. …”

Intraperitoneal hinokitiol injection does not decrease the number of live bacteria in BALF. by Toshihito Isono (8587668)

Concentrations of particles that caused significant decreases in the viability of SNU-1 cells compared to untreated cells during 1, 2, 4, 6 or 24 h treatment periods. by Amrita Banerjee (382658)

Inflammatory cell infiltration in infected tissue is decreased in the AG treated group. by Mario C. Salinas-Carmona (9553084)

Decreased number of cones and retinal ganglion cells in Oc-deficient retina. by Michaela Kreplova (9239560)

Intensity-modulated proton therapy decreases dose to organs at risk in low-grade glioma patients: results of a multicentric <i>in silico</i> ROCOCO trial by Daniëlle B. P. Eekers (5560430)

Umbelliprenin treatment decreases the activity of the TCF reporter in gastric cancer cells. by Lijing Zhang (463702)

GTDE decreased the expression of the NLRP3 inflammasome and AGEs in the cerebral cortex. by Hui-Chuan Kuo (12368492)

Exposure to exogenous antioxidants prior to osmotic stress decreases tardigrade survival. by Amanda L. Smythers (9077730)

NatB-inactivation decreased Drk levels through its N-terminal sequences, which was regulated by the N-end rule E3 ubiquitin ligase POE/UBR4. by Zhentao Sheng (107495)

Placental aromatase expression decreased in severe neonatal opioid withdrawal syndrome by Courtney Townsel (6705368)

siRNA Knockdown of PKCδ decreases phosphorylation of VEEV capsid. by Brian D. Carey (6092747)

rHSP60 decreases LPS-induced mononuclear cell proliferation. by Igor Emiliano L. Souza (18196495)

A high-salt high fat diet decreased locomotor activity but did not alter circadian rhythm. by Yoko Yokoyama (394202)

Conditions that ablate cytonemes decrease signaling, reduce myoblast and tumor growth. by Sol Fereres (664350)

PAM16 correlation with N-MYC. by Zahra Motahari (6814013)

TG6-44 treatment decreases A/X31-induced ROS in THP-1 cells. by Juan A. De La Cruz (11154187)

Effects of 1466 on capsid and pgRNA encapsidation compared to known CAM-A and CAM-E inhibitors. by Daniel P. Bradley (10306893)

Subjects:

Discovery of Novel Pyrimidine-Based Capsid Assembly Modulators as Potent Anti-HBV Agents by WooChan Kim (10690503)

“…One of the synthesized derivatives, compound <b>23h</b> (R¹ = MeSO₂, R² = 1-piperidin-4-amine, R³ = 3-Cl-4-F-aniline) displayed potent inhibitory effects in the in vitro assays (52% inhibition in the protein-based assay at 100 nM and an IC₅₀ value of 181 nM in the serum HBV DNA quantification assay). …”