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    The frequency of co-expression of ALDH and CGA progressively decreases during colon tumorigenesis in FAP patients. by Tao Zhang (43681)

    Published 2020
    “…Fig 2F shows that in normal crypts, many cells staining for the colonic SC marker ALDH1 co-stained for chromogranin-A (CGA) and other NEC markers. In contrast, in <i>APC</i>-mutant tissues from familial-adenomatous-polyposis (FAP) patients, the proportion of ALDH+/CGA+ SCs progressively increased while ALDH+/CGA–PNCs, and ALDH+/CGA–NECs progressively decreased. …”