Data_Sheet_1_Dynamic Changes and Prognostic Value of Gut Microbiota-Dependent Trimethylamine-N-Oxide in Acute Ischemic Stroke.doc by Chuhong Tan (6292904)

“…</p><p>Results: TMAO levels showed no significant changes before and within 24 h of AIS treatment (at admission) but decreased significantly thereafter. Elevated log₂-transformed baseline TMAO levels were associated with increased risks of 90-day [odds ratio (OR), 2.62; 95% confidence interval (CI), 1.55–4.45; p < 0.001] and 12-month (OR, 3.59; 95% CI, 2.12–6.09; p < 0.001) major ischemic events, as well as 90-day (OR, 2.89; 95% CI, 1.46–5.71; p = 0.002) and 12-month (OR, 2.58; 95% CI, 1.50–4.46; p = 0.001) unfavorable functional outcomes, after adjustments for confounding factors. …”

Aerobic Exercise Inhibits Sympathetic Nerve Sprouting and Restores β-Adrenergic Receptor Balance in Rats with Myocardial Infarction by Ting Chen (15205)

“…<div><p>Background</p><p>Cardiac sympathetic nerve sprouting and the dysregulation of β-adrenergic receptor (β-AR) play a critical role in the deterioration of cardiac function after myocardial infarction (MI). …”

Image_1_Safety and Immunological Evaluation of Interleukin-21 Plus Anti-α4β7 mAb Combination Therapy in Rhesus Macaques.jpg by Maria Pino (109981)

“…<p>Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infections compromise gut immunological barriers, inducing high levels of inflammation and a severe depletion of intestinal CD4⁺ T cells. …”

Table_1_Safety and Immunological Evaluation of Interleukin-21 Plus Anti-α4β7 mAb Combination Therapy in Rhesus Macaques.docx by Maria Pino (109981)

“…<p>Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infections compromise gut immunological barriers, inducing high levels of inflammation and a severe depletion of intestinal CD4⁺ T cells. …”

Table1_Longitudinal Trend of Plasma Concentrations of Extracellular Vesicles in Patients Hospitalized for COVID-19.DOCX by Elena Campello (11953730)

“…Blood samples of consecutive COVID-19 patients admitted to a medical Unit were longitudinally collected within 48 h of admission, at discharge and 30 days post-discharge. …”

Adiponectin Modulates Oxidative Stress-Induced Autophagy in Cardiomyocytes by Eric E. Essick (435031)

“…., “HF with preserved ejection fraction” (HF-preserved EF) accounts for up to 50% of all HF presentations; however there have been no therapeutic advances. …”

Table_2_Safety and Immunological Evaluation of Interleukin-21 Plus Anti-α4β7 mAb Combination Therapy in Rhesus Macaques.docx by Maria Pino (109981)

“…<p>Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infections compromise gut immunological barriers, inducing high levels of inflammation and a severe depletion of intestinal CD4⁺ T cells. …”

Image_2_Safety and Immunological Evaluation of Interleukin-21 Plus Anti-α4β7 mAb Combination Therapy in Rhesus Macaques.jpg by Maria Pino (109981)

“…<p>Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infections compromise gut immunological barriers, inducing high levels of inflammation and a severe depletion of intestinal CD4⁺ T cells. …”

Table_1_The efficacy and safety of anti-vascular endothelial growth factor combined with Ahmed glaucoma valve implantation in the treatment of neovascular glaucoma: a systematic re... by Chang-Zhu He (19267120)

“…Compared with AGVI alone, the combination of anti-VEGF drugs and AGVI can reduce postoperative intraocular pressure (IOP) at 1 week [WMD = −4.03, 95% CI (−5.73, −2.34), p < 0.001], 1 month [WMD = −5.39, 95% CI (−7.05, −3.74), p < 0.001], 3 months [WMD = −6.59, 95% CI (−7.85, −5.32), p < 0.001], 6 months [WMD = −4.99, 95% CI (−9.56, −0.43), p = 0.032], and more than 12 months [WMD = −3.86, 95% CI (−6.82, −0.90), p = 0.011], with a higher Effective rate [RR = 1.27, 95% CI (1.18, 1.37), p < 0.001], decreased incidence of postoperative hyphema [RR = 0.24, 95% CI (0.15, 0.39), p < 0.001], reduced use of postoperative antiglaucoma medications [WMD = −0.48, 95% CI (−0.61, −0.35), p < 0.001], and decreased aqueous humor VEGF levels [SMD = −2.84, 95% CI (−4.37, −1.31), p < 0.001].…”

Data_Sheet_1_Physiological Changes, Activity, and Stress During a 100-km–24-h Walking-March.docx by Marc Jörres (10288175)

“…All serum parameters were analyzed for correlation concerning different MET levels, speed, age, BMI, baseline NT-pro-BNP, mean heart rate during the race, and sex with linear regression analysis.</p>Results<p>We found significant elevations for muscle and cardiac stress markers (CRP, CK, CK-MB, AST, ALT, cortisol, and NT-pro-BNP) as well as decreasing markers of lipid metabolism (cholesterol, triglycerides, LDL). …”

DataSheet_1_Efficacy of flavonoids-containing supplements on insulin resistance and associated metabolic risk factors in overweight and obese subjects: a systematic review and meta... by Jia Yao (323339)

“…Flavonoids, with anti-inflammatory and antioxidative functions, are proposed to treat insulin resistance (IR) in obese subjects. We aimed to evaluate the effectiveness and safety of flavonoids-containing supplements on IR and associated metabolic risk factors in overweight and obese participants.…”

Table_1_Global, regional, and national HIV/AIDS disease burden levels and trends in 1990–2019: A systematic analysis for the global burden of disease 2019 study.docx by Xuebin Tian (7402760)

“…Age-standardized prevalence, death, and DALY rates decreased in high sociodemographic index (SDI) areas. …”

Differential microRNA expression in human placentas of term intra-uterine growth restriction that regulates target genes mediating angiogenesis and amino acid transport by Shanthie Thamotharan (3992894)

“…<i>In-vitro</i> nutrient deprivation (~50%) increased the expression of <i>miR-10b</i> and <i>miR-149</i> by 1.5-fold (p<0.02) while decreasing <i>miR-363</i> (p<0.0001). …”

LGG-1 foci formation following UV irradiation in hermaphrodite and male gonads. by Hyemin Min (6733586)

“…The non-irradiated gonad appeared not different from the ones at the 0.5 h and 3 h time points. (6 h) LGG-1 foci largely disappeared, whereas PGL-1 was lost from around 50% of germ cells (a cluster of blue germ nuclei) in the pachytene region of the UV-irradiated gonad. …”

S1 Data - by Dénes Pauka (16955686)

“…Specimens were examined by a Zwick/Roell Z5.0 biaxial tester. The Young’s modulus (<i>E</i> (MPa)) was calculated using a linear regression procedure where the base of the elongation was the parallel length of the sample, the achieved maximal force (<i>F</i>_max (N)), the elongation at the time of <i>F</i>_max (<i>L</i>_max (mm)), the force at the beginning of rupture (<i>F</i>_break (N)), the elongation at the time of <i>F</i>_break (<i>L</i>_break (mm)) were registered. …”

Root Zone Organic Matter Effects on Creeping Bentgrass Growth in Controlled Environments by Maureen Kahiu (20834468)

“…Inorganic N within cores from putting greens in the high and medium SOM groups increased more than those from the low SOM group, suggesting a greater percentage of inorganic N was allocated for CBG growth. …”

Table1_The long-term prognostic implications of free triiodothyronine to free thyroxine ratio in patients with obstructive sleep apnea and acute coronary syndrome.jpg by Yun Zhou (308977)

“…The free triiodothyronine to free thyroxine (FT3/FT4) ratio as a novel biomarker of cardiovascular disease prognosis, but the impact of the FT3/FT4 ratio on the prognosis of OSA in patients with acute coronary syndromes (ACS) remains uncertain.…”

Data_Sheet_1_Actinobacteria and Cyanobacteria Diversity in Terrestrial Antarctic Microenvironments Evaluated by Culture-Dependent and Independent Methods.pdf by Adriana Rego (6760589)

“…Data derived from HTS show that the percentage of cyanobacteria decreases from about 20% in the sample closest to the water source to negligible values on the last three samples of the transect with less water availability. …”

Image_1_Maternal Tn Immunization Attenuates Hyperoxia-Induced Lung Injury in Neonatal Rats Through Suppression of Oxidative Stress and Inflammation.TIF by Chung-Ming Chen (2155318)

“…Furthermore, the alleviation of lung injury was accompanied by a reduction in lung cytokine and 8-OHdG expression. …”

Effects of high dissolved inorganic and organic carbon availability on the physiology of the hard coral Acropora millepora from the Great Barrier Reef by Friedrich Meyer (1403593)

“…This experimental study investigated the individual and combined effects of ambient and high</p> <p>DIC (<i>p</i>CO₂ 403 μatm/ pH_Total 8.2 and 996 μatm/pH_Total 7.8) and DOC (added as Glucose 0 and</p> <p>294 μmol L^-1, background DOC concentration of 83 μmol L^-1) availability on the physiology (net and gross photosynthesis, respiration, dark and light calcification, and growth) of the scleractinian coral <i>Acropora millepora</i> (Ehrenberg, 1834) from the Great Barrier Reef over a 16 day interval. High DIC availability did not affect photosynthesis, respiration and light calcification, but significantly reduced dark calcification and growth by 50 and 23%, respectively. …”