A decrease in CD44+ cells in response to hypoxia. by Daniel V. Brown (3797809)

Suppression of the growth defects in flippase mutants by decreased synthesis of PI. by Kanako Yamagami (703555)

Tranilast decreases OC formation induced by RANKL. by Tien Van Phan (583324)

The Intracellular level of FLASH decreases during apoptosis. by Song Chen (69646)

Transcriptional and translational markers of syncytialization and biochemical differentiation are significantly decreased by rotenone. by O’Llenecia S. Walker (8486163)

IL-1Ra expressed by MSCs decreased Th17 differentiation. by Kijun Lee (4888660)

PV1-treated mice exhibited a decrease in overall activation of T lymphocytes. by Pedro Henrique Papotto (791904)

LPS decreases only T cell proliferative response to OKT3. by Fanny Poujol (834338)

h-GAAP Decreases Cell Susceptibility to Extrinsic Apoptosis Pathways by Caroline Gubser (24818)

Cilostazol decreases OC formation and bone resorption induced by RANKL. by Ke Ke (583325)

Lethal toxin decreases IL-22 production in human ILCs. by Sudarshan Seshadri (370894)

Rabankyrin-5 Overexpression Increases, whereas Knock-Down Decreases Fluid-Phase Uptake, Specifically by Carsten Schnatwinkel (48)

Brivanib decreases viability of PDGF-BB treated LX-2 cells. by Ikuo Nakamura (548298)

“…Cells showed a brivanib dose-dependent decrease in viability, with half maximal inhibitory concentration (IC₅₀) of 16.98 µM (95% CI 13.95 µM–20.67 µM). …”

Thimerosal decreases the expression of survivin via the PI3K/Akt pathway. by Wen-Xue Li (189757)

MCP-1-deficiency decreased CD11c-expressing cells via impairing the production of ROS and decreased activation of PLCγ2, Akt, and ERK upon M-CSF stimulation in BMM. by Woon-Ki Kim (447798)

“…<p>BMMs from WT (open bar) and MCP-1-KO mice (oblique-lined bar) were incubated in the presence of M-CSF (30 ng/ml) with U73122 (10 µM), Akt inhibitor IV (0.3 µM), PD098059 (5 µM), DPI (50 nM), NAC (3 mM), or H₂O₂ (300 µM) for 4 d (A). *, <i>P</i><0.05; ***, <i>P</i><0.001 compared with vehicle-treated WT cells. …”

Bay 61–3606 sensitizes MCF-7 cells to TRAIL by decreasing Mcl-1. by So-Young Kim (562174)

mPEG PV1-Fab’ treatment decreases T_reg population. by Pedro Henrique Papotto (791904)

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…<i>N</i>-(4-Bromophenyl)-4-(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-6-morpholino-1,3,5-triazin-2-amine <b>4f</b>, <i>N</i>-(4-chlorophenyl)-4,6-bis­(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-1,3,5-triazin-2-amine <b>5c</b>, and 4,6-<i>bis</i>(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-<i>N</i>-(4-methoxyphenyl)-1,3,5-triazin-2-amine <b>5d</b> showed promising activity against these cancer cells: <b>4f</b> [(IC₅₀ = 4.53 ± 0.30 μM (MCF-7); 0.50 ± 0.080 μM (HCT-116); and 3.01 ± 0.49 μM (HepG2)]; <b>5d</b> [(IC₅₀ = 3.66 ± 0.96 μM (HCT-116); and 5.42 ± 0.82 μM (HepG2)]; and <b>5c</b> [(IC₅₀ = 2.29 ± 0.92 μM (MCF-7)]. …”

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…<i>N</i>-(4-Bromophenyl)-4-(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-6-morpholino-1,3,5-triazin-2-amine <b>4f</b>, <i>N</i>-(4-chlorophenyl)-4,6-bis­(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-1,3,5-triazin-2-amine <b>5c</b>, and 4,6-<i>bis</i>(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-<i>N</i>-(4-methoxyphenyl)-1,3,5-triazin-2-amine <b>5d</b> showed promising activity against these cancer cells: <b>4f</b> [(IC₅₀ = 4.53 ± 0.30 μM (MCF-7); 0.50 ± 0.080 μM (HCT-116); and 3.01 ± 0.49 μM (HepG2)]; <b>5d</b> [(IC₅₀ = 3.66 ± 0.96 μM (HCT-116); and 5.42 ± 0.82 μM (HepG2)]; and <b>5c</b> [(IC₅₀ = 2.29 ± 0.92 μM (MCF-7)]. …”

Ang II decreases brain hemorrhages, delays experimental cerebral malaria and increases survival of mice. by Julio Gallego-Delgado (796586)