IL-17A promotes the expression of osteoclast-related genes involved in osteoclastogenesis. by Hao Tang (44155)

Multiple homologs of 16p12.1 genes contribute to neurodevelopmental defects in <i>Drosophila melanogaster</i> and <i>X</i>. <i>laevis</i>. by Lucilla Pizzo (2735491)

“…<i>laevis</i> represents controls injected with the highest amount of morpholino (50 ng, see <b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009112#pgen.1009112.s005" target="_blank">S5 Fig</a></b>). …”

Kylo-0603’s EC50 & tissue levels. by Xueqin lu (22250795)

IL-17A inhibits apoptosis of OCPs. by Hao Tang (44155)

IL-17A promotes RANKL-stimulated osteoclastogenesis. by Hao Tang (44155)

Homologs of 16p12.1 genes contribute towards neurodevelopmental defects through weak genetic interactions and combined independent effects. by Lucilla Pizzo (2735491)

“…<p>(<b>A</b>) We generated eye-specific <i>GMR-GAL4</i> recombinant lines for the four 16p12.1 homologs to test a total of twelve pairwise interactions for modulation of eye defects. …”

Inhibition of autophagy attenuates IL-17A-mediated osteoclastogenesis. by Hao Tang (44155)

The number of overrepresented short sequences decreases as infection progresses. by MiYao Hu (7865549)

Analytical sensitivity and reproducibility. by Lizhi Yu (12476136)

Depth of coverage and heterogeneity of the mutation loci. x-axis, mutation loci in sample set one or two; y-axis, depth of coverage after UMI consolidation. by Lizhi Yu (12476136)

Quantification and accuracy of average VAF. by Lizhi Yu (12476136)

Schematic overview of the cross-platform study. by Lizhi Yu (12476136)

Impact of DNA extraction process on depth of coverage. by Lizhi Yu (12476136)

Absence of neocortex is associated with a dorsal shift of piriform cortex in <i>Emx1</i>-cKO mice. by Sathish Venkataramanappa (10331993)

<b>Adipose TGR5 deletion promotes hepatic steatosis through decreasing adiponectin secretion in mice</b> by Jiahui Li (646449)

Supplementary Figures 1-8 from Targeting Notch Signaling with a Notch2/Notch3 Antagonist (Tarextumab) Inhibits Tumor Growth and Decreases Tumor-Initiating Cell Frequency by Wan-Ching Yen (11520727)

ACR-16 is conserved in clade III worms. by Jennifer D. Noonan (14117157)

Relative expression of (A) miR-214 and (B) the <i>ATF4</i> target gene after transfection with 40 nM of miR-214 mimics or a negative mimics control for 24 h, followed by treatment... by Tipparat Penglong (164413)

Discovery of the Diphenyl 6‑Oxo-1,6-dihydropyridazine-3-carboxylate/carboxamide Analogue J27 for the Treatment of Acute Lung Injury and Sepsis by Targeting JNK2 and Inhibiting the... by Jing Liao (193197)

“…The optimal compound <b>J27</b> decreased the release of TNF-α and IL-6 in mouse and human cells J774A.1 and THP-1 (IL-6 IC₅₀ = 0.22 μM) through the NF-κB/MAPK pathway. …”

Discovery of the Diphenyl 6‑Oxo-1,6-dihydropyridazine-3-carboxylate/carboxamide Analogue J27 for the Treatment of Acute Lung Injury and Sepsis by Targeting JNK2 and Inhibiting the... by Jing Liao (193197)

“…The optimal compound <b>J27</b> decreased the release of TNF-α and IL-6 in mouse and human cells J774A.1 and THP-1 (IL-6 IC₅₀ = 0.22 μM) through the NF-κB/MAPK pathway. …”