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19761
Pituitary Adenylate Cyclase Activating Peptide Deficient Mice Exhibit Impaired Thymic and Extrathymic Regulatory T Cell Proliferation during EAE
Published 2013“…In addition to these Treg alterations, a specific reduction of Th2 cells (about 4-fold) was observed in the lymph nodes in PACAP KO mice, with no effects on Th1 and Th17 subsets, whereas in the CNS, Th1 and Th17 cells were increased and Th2 decreased. …”
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19762
Macrophages Have Distinct Transcriptional Responses to Vacuolar and Cytosolic L. monocytogenes Infection
Published 2008“…Red indicates an increase in RNA abundance relative to uninfected macrophages, and green indicates a decrease. Genes identified by SAM and at least 4-fold induced in WT macrophages by <i>hly− L. monocytogenes</i> are indicated as targets of the “Vacuolar Response”. …”
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19763
The MEDII-associated mesoderm suppressing activity is found within the small molecular weight components of the medium.
Published 2013“…Aggregates were transferred to unsupplemented medium or medium supplemented with 50% MEDII, 50% E or R and cultured for a further 2 days before reduction to a single cell suspension. …”
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19764
Data Sheet 1_Impact of fluoxetine exposure on Lymnaea stagnalis and its developing eggs: integrating untargeted lipidomics, targeted metabolomics, and classical risk assessment.doc...
Published 2025“…In the albumen gland, we detected a decrease of key lipid classes, including sphingomyelins and fatty acids, which can be linked with impaired egg quality. …”
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19765
Quantification of total Shc protein levels by semi-quantitative immunofluorescence following RNAi-mediated knockdown of p66Shc in early bovine embryos.
Published 2014“…Embryos injected with either RNAi-A or RNAi-E siRNAs exhibited a significant decrease in Shc protein levels. …”
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19766
SRM measurements of a subset of <i>C. jejuni</i> metabolic enzymes.
Published 2012“…</p>3<p>Fold change of fragment ion intensities between the 2 h and 20 h samples; negative values denote decreased levels in the 20 h samples.…”
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19767
The effects of PC1, PC2 and IFT88 siRNA knockdown on hASC primary cilia.
Published 2013“…Cilia expression on hASC: (a) Non-targeting scramble siRNA baseline cilia expression on approximately 50% of the hASC population (b) PC1 and (c) PC2 knockdown conditions express more cilia observed in a curved conformation and a minimal decrease in cilia population frequency, (d) IFT88 knockdown confers a reduction in cilia frequency on the hASC population. …”
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19768
Effect of RAMP1 mRNA knockdown on TT cells.
Published 2014“…<p>(A) mRNA expression levels of RAMP1, RAMP2 and CaSR in TT cells transfected with RAMP1 or scrambled siRNA, 72 hr post-transfection expressed as fold change normalised to Actβ. …”
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19769
Suppressive effect of AMP-activated protein kinase on the epithelial-mesenchymal transition in retinal pigment epithelial cells
Published 2017“…In this study, EMT-associated formation of cellular aggregates was induced by co-stimulation of cultured ARPE-19 cells with tumor necrosis factor (TNF)-α (10 ng/ml) and transforming growth factor (TGF)-β<sub>2</sub> (5 ng/ml). 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR), a potent activator of AMPK, significantly suppressed TNF-α and TGF-β<sub>2</sub>-induced cellular aggregate formation (p < 0.01). …”
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19770
Induction of intracellular metabolic activators by sofosbuvir.
Published 2024“…The gene expression was shown as fold-changes over the corresponding untreated groups. imHC and Huh7 were infected with HCVcc (genotype 2a) at MOI 1 and subsequently exposed to various concentrations of sofosbuvir for 7 days. …”
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19771
Chromatin relaxation affects spliceosome recruitment to nascent RNA and binding of splicing factors to ncRNAs.
Published 2012“…Each junction was analyzed separately, and for each junction genes included in the analysis (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0048084#s3" target="_blank">Materials and Methods</a>) were divided into categories of increased (Up), decreased (Down) or unchanged (less than 2-fold change in any direction) U2AF65 counts in a region of +/−100 nt around the corresponding junction. …”
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19772
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19773
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19774
Sequential Injection Analysis of Butyrylcholinesterase Using Butyrylcholine Ion-Selective Electrode Detector (Supporting Information)
Published 2022“…In the present SIA method using the BuCh-ISE detector based on <i>α</i>-cyclodextrin membrane, BChE in the concentration range of 0.015–0.50 units/mL was determined at a BuCh concentration of 2.0 mmol dm<sup>−3</sup> and a reaction time of 5.0 min. …”
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19775
Effect of Squeeze Casting on Microhardness and Microstructure of Al-3Cu-xSi Alloy
Published 2019“…This process provides changes in the microstructure which lead to changes in the mechanical properties of the material such as the increase in the microhardness of the processed alloy. alloys Al-5,5% Si-3% Cu, Al-7,5% Si-3% and Al-9% Si-3% Cu alloys were solidified by the squeeze casting process to analyze the microstructural and microhardness variations. Pressures of 0 MPa, 50 MPa, 100 MPa and 150 Mpa were used. In general, with increasing pressure and composition, the λ2 values decrease from the metal/mold interface, especially at pressures of 150 MPa and Composition of 9%Si, on the other hand the increase of these variables leads to the formation of more phases Al2Cu metastable that have a decrease in the Microhardness of the material, in addition to the formation of other phases due to the proximity to the eutetic.…”
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19776
Table_1_Circular RNA Expression Profiling Identifies Glaucoma-Related Circular RNAs in Various Chronic Ocular Hypertension Rat Models.XLS
Published 2020“…Furthermore, 3,502 differentially expressed circular RNAs verified in both COH rats were identified, of which 691 were upregulated and 2,811 were downregulated. Seven significantly downregulated (both log<sub>2</sub>FoldChange < −2.5 and adjusted P < 0.001) and seven significantly upregulated (both log<sub>2</sub>FoldChange > 2.5 and adjusted P < 0.001) circular RNAs were shown. …”
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19777
Fig 3 -
Published 2024“…Range of bTB prevalence changes for 50% changes in harvest rates in Alpena County. The upper dashed line represents results for a 50% decrease in harvest rate, lower represents the result for a 50% increase in harvest rate and the solid line represents baseline predictions (maintaining harvest at current levels).…”
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19778
Depiction of the TMH.
Published 2020“…This is because the relationship within this range is predicted to be monotonic and, with error, might often be well fit with a line or some other monotonic function. Given this, the TMH has often been tested 1 of 2 ways: <b>(e)</b> by testing for the effect of a statistical interaction between the temperature during disease sampling and the temperature to which host are adapted (usually measured as the 50-year mean temperature at the location of their collection) on infection probability or <b>(f)</b> by testing for a negative relationship between the 50-year mean temperature of hosts and the temperature of peak prevalence minus the 50-year mean temperature of hosts. …”
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19779
EHEC-Hly-containing OMVs cause DNA laddering and formation of TUNEL-positive nuclei.
Published 2013“…<p>(<b>A, B</b>) HBMEC (<b>A</b>) and Caco-2 cells (<b>B</b>) were incubated with EHEC-Hly-containing OMVs (TA50 or 8033; 100 ng of EHEC-Hly) or EHEC-Hly-free OMVs (TA51 or 8033c; 20 µg of OMV protein) for 48 h. …”
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19780
THE FREQUENCY AND DISTRIBUTION OF SISTER CHROMATID EXCHANGES (SCES) IN THE INDIVIDUAL CHROMOSOMES OF HUMAN KA¬RYOTYPE
Published 2020“…<p>The difference in the number of SCEs found per cell in 50 mitoses of control subjects when evaluated from photomicrographs or karyotypes is small but significant (p< 0.01). …”