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AKT inhibition decreases neuroblast populations.
Published 2012“…Otic vesicles were isolated from HH18 chicken embryos, made quiescent and cultured for 20 h in serum-free culture medium without additions (0S, a) or in the presence of IGF-I (10 nM, b), LY294002 (LY, 25 µM, c) or AKTi VIII (AKTi, 50 µM, d). …”
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Resveratrol decreases PKM2 expression.
Published 2013“…<p>Resveratrol treatment decreases PKM2 mRNA in (A), HeLa; (B), HepG2 and (C), MCF-7; by approximately two-folds. β-actin was taken as endogenous control and normalized to PKM2 mRNA. …”
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ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulat...
Published 2011“…<p><b>Copyright information:</b></p><p>Taken from "ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of γ-secretase activity"</p><p>http://www.molecularneurodegeneration.com/content/2/1/14</p><p>Molecular Neurodegeneration 2007;2():14-14.…”
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At lower concentrations, METH decreases LTP.
Published 2010“…<p>At higher concentrations, METH increases baseline synaptic transmission and decreases LTP. (<b>A</b>) Summary plot of normalized fEPSP slope measurements recorded in the CA1 region of the hippocampus. …”
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Isoflurane decreased miR-214.
Published 2013“…M-miR-214: mimic miR-214; I-miR-214: miR-214 inhibitor. (<b>E</b>) miR-214 decreased Bax expression in a dose-dependent manner. …”
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