Discovery of N‑Substituted Acetamide Derivatives as Promising P2Y₁₄R Antagonists Using Molecular Hybridization Based on Crystallographic Overlay by Wenjin Liu (4016060)

“…Thus, compound <b>I-17</b>, with potent P2Y₁₄R antagonistic activity, <i>in vitro</i> and <i>in vivo</i> efficacy, and favorable bioavailability (<i>F</i> = 75%), could be a promising lead compound for acute gouty arthritis.…”

Discovery of N‑Substituted Acetamide Derivatives as Promising P2Y₁₄R Antagonists Using Molecular Hybridization Based on Crystallographic Overlay by Wenjin Liu (4016060)

“…Thus, compound <b>I-17</b>, with potent P2Y₁₄R antagonistic activity, <i>in vitro</i> and <i>in vivo</i> efficacy, and favorable bioavailability (<i>F</i> = 75%), could be a promising lead compound for acute gouty arthritis.…”

Predicted <i>cis</i>-acting elements in <i>DpAP2</i> promoter. by Lingru Ruan (18995544)

“…<i>parva</i> cells treated with different concentrations of MeJA (10, 20, 50, 100 μM) and GA3 (10, 20, 50, 100 μM). The high concentrations of MeJA (10–100 μM) inhibited the accumulation of carotenoid, and the relative expression of <i>DpAP2</i>, <i>PSY</i>, <i>PDS</i> and <i>GGPS</i> decreased significantly. …”

Synprint mediates the coupling of IRP with P/Q-type calcium channels. A: by Yanina D. Álvarez (277954)

“…Please note that while Syn⁻, EGFP and Syn⁺ have almost identical I_Ca2+ values, a highly significant decrease (p<0.005) in the IRP exocytosis was found between Syn⁺ and the other two groups of experiments. …”

Serum EVs of iFIRKO mice promote hepatocyte proliferation <i>in vitro</i>. by Yoshihiro Niitsu (14249456)

The Combination of Quantitative Proteomics and Systems Genetics Analysis Reveals that PTN Is Associated with Sleep-Loss-Induced Cognitive Impairment by Yutong Zhou (5492852)

Correlations among clinical illness signs. by Aiden E. Juge (12986438)

Analysis of MD simulations for the SP domain of native PC and its mutant structures (L305R, W342C, G403R, V420E, and W444C) over 200 ns simulations. by Mahvash Farajzadeh-Dehkordi (17468232)

Mild hypoxic-ischemic encephalopathy piglet model. by Dawn B. Lammert (21175128)

Imbalanced Dataset Distribution. by Mudhafar Jalil Jassim Ghrabat (22177655)

“…We surpassing other models as such, CNN, VGG19, ResNet50.</p></div>…”

Data Preprocessing Steps for IDC Dataset. by Mudhafar Jalil Jassim Ghrabat (22177655)

“…We surpassing other models as such, CNN, VGG19, ResNet50.</p></div>…”

Flowchart of Proposed SMO_CNN. by Mudhafar Jalil Jassim Ghrabat (22177655)

“…We surpassing other models as such, CNN, VGG19, ResNet50.</p></div>…”

IDC Breast Cancer Dataset Descriptions. by Mudhafar Jalil Jassim Ghrabat (22177655)

“…We surpassing other models as such, CNN, VGG19, ResNet50.</p></div>…”

Accuracy Graph. by Mudhafar Jalil Jassim Ghrabat (22177655)

“…We surpassing other models as such, CNN, VGG19, ResNet50.</p></div>…”

Loss Graph. by Mudhafar Jalil Jassim Ghrabat (22177655)

“…We surpassing other models as such, CNN, VGG19, ResNet50.</p></div>…”

Hyperparameter Tuning of the Proposed Model. by Mudhafar Jalil Jassim Ghrabat (22177655)

“…We surpassing other models as such, CNN, VGG19, ResNet50.</p></div>…”

Comparison of Accuracy Metric. by Mudhafar Jalil Jassim Ghrabat (22177655)

“…We surpassing other models as such, CNN, VGG19, ResNet50.</p></div>…”

ROC Curve for the Best Model (AUC = 0.92). by Mudhafar Jalil Jassim Ghrabat (22177655)

“…We surpassing other models as such, CNN, VGG19, ResNet50.</p></div>…”

Sampling Images of IDC Dataset. by Mudhafar Jalil Jassim Ghrabat (22177655)

“…We surpassing other models as such, CNN, VGG19, ResNet50.</p></div>…”

CNN Model Layers Summary. by Mudhafar Jalil Jassim Ghrabat (22177655)

“…We surpassing other models as such, CNN, VGG19, ResNet50.</p></div>…”