Discovery of Urea Derivatives of Celastrol as Selective Peroxiredoxin 1 Inhibitors against Colorectal Cancer Cells by Yang Li (7082)

“…Herein, a series of celastrol urea derivatives were developed based on its cocrystal structure with PRDX1, with the aim of pursuing a PRDX1-specific inhibitor. …”

Association of metabolic syndrome and psoriasis severity. by Dina Evyana (18462048)

Sociodemographic characteristic of the study population. by Dina Evyana (18462048)

Baseline clinical characteristic of the study population. by Dina Evyana (18462048)

Prevalence of metabolic syndrome (MetS) in hard-to-treat psoriasis. by Dina Evyana (18462048)

Elevated IL-18, NF-κB p65, and YY1 expression and decreased FXR and MRP2 were observed in the BDL rats. by Xiao-cong Liu (785281)

IκBαM.1-Infected Mice Have Decreased Latency in Lung B Cells 16 dpi after Intranasal Infection by Laurie T Krug (68237)

DC-based vaccination decreases the early secretion of IL-10 by CD4⁺ T cells following infection with <i>L. major</i> by Tobias Schwarz (241564)

NSE-apoE4, but not GFAP-apoE4, mice have decreased spine density in the auditory cortex at 19–21 months of age. by Sachi Jain (108277)

Decreasing fitness over time observed following analysis of paired isolates obtained from acute HIV-1 infection subjects, measured using QPCR. by Alicia Arnott (242179)

Range of SARS-CoV-2% memory B cells among participants with hybrid immunity, by number of spike exposure*—Georgia, December 2020– July 2022, n = 15. by Zeshan A. Chisty (18388200)

Thy1-p45 transgenic mice have decreased retraction of CST fibers and improved functional recovery following SCI compared to their WT littermates. by Tsung-Chang Sung (436234)

Increased NO from X-CGD neutrophils stimulated by A23187 is associated with the decreased of H₂O₂ production. by Akari Nakamura-Utsunomiya (8677080)

Study population: patients living with comorbidities (on the left) and immunosuppressive conditions (on the right) who are at risk of pneumococcal disease in France in the year 202... by Benjamin Wyplosz (22032756)

Diabetes increases A_2AR density and decreases A₁R density in hippocampal nerve terminals. by João M. N. Duarte (326380)

Decreased IL-17A production by DGKζ deficient <i>i</i>NKT cells following α-GalCer stimulation in vitro. by Jinhong Wu (424170)

Activation of the glucocorticoid receptor increases expression of the MKP-1/DUSP1 gene and decreases IL-1β-stimulated p38 MAPK phosphorylation. by Susan J. Burke (130329)

The proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases in <i>APC</i>-mutant colon tissues from FAP patients. by Tao Zhang (43681)

“…<p>Representative IHC stains of normal, normal-appearing FAP, and FAP adenomatous colonic crypts are shown for the expression of the: <b>(A)</b> NEC marker chromogranin-A (CGA). <b>(B)</b> SC marker ALDH1. …”

PPARγ inhibition decreased effects of MAG incubation on PPARγ expression and insulin-stimulated signaling pathway in human umbilical vein endothelial cells. by Xiangyan Liang (431205)

UV-irradiated M phase-cells show decreased MCM 2–7 loading and G1 arrest after release: HeLa cells. by Masayuki Morino (304956)