Ludmila Belayev 12-point scoring between groups. by Guangxiao Ni (19713106)

“…MiR-199a-5p decreased the expression of PIK3R2 after MCAO, activated Akt signaling pathway, and increased the expression of Claudin-5 and VEGF in the ischemic penumbra. …”

High fat diet decreased tumor latency but did not affect survival in MMTV-PyMT transgenic mice. by Katherine V. Clark-Knowles (368164)

The injectable contraceptives depot medroxyprogesterone acetate and norethisterone enanthate substantially and differentially decrease testosterone and sex hormone binding globulin... by Chanel Avenant (409756)

“…<p dir="ltr">HIV acquisition risk with norethisterone (NET) enanthate (NET-EN) is reportedly less than for depo-medroxyprogesterone acetate intramuscular (DMPA-IM). We investigated the effects of these progestin-only injectable contraceptives on serum testosterone and sex hormone binding globulin (SHBG) levels, since these may play a role in sexual behavior and HIV acquisition. …”

Lifespan is decreased in <i>P[syt^P-L]</i> heterozygotes. by Mallory C. Shields (4474210)

Extracellular adenosine modulates host-pathogen interactions through regulation of systemic metabolism during immune response in <i>Drosophila</i> by Adam Bajgar (730380)

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

Linear decrease of delta power (1.1–5.0 Hz) across the first three sleep cycles in the cortical, hippocampal and scalp recordings. by Fabio Moroni (34208)

Compound CID 9998128 Is a Potential Multitarget Drug for Alzheimer’s Disease by Nguyen Quoc Thai (5348798)

“…We have probed small molecule compound CID 9998128 as a potential multitarget drug for the Alzheimer’s disease (AD) using <i>in silico</i> and <i>in vitro</i> experiments. …”

Compound CID 9998128 Is a Potential Multitarget Drug for Alzheimer’s Disease by Nguyen Quoc Thai (5348798)

“…We have probed small molecule compound CID 9998128 as a potential multitarget drug for the Alzheimer’s disease (AD) using <i>in silico</i> and <i>in vitro</i> experiments. …”

Pancreatic cancer cell proliferation is decreased upon M344 treatment. by Shelby M. Knoche (13833807)

Selected point of entry health desks. by Aney Rijal (21262075)

“…<div><p>Purpose</p><p>This research aimed to identify the barriers and facilitators in implementation fidelity of malaria screening at Nepal-India border Point of Entry (POE) health desks.</p><p>Method</p><p>A mixed-method approach was used guided by an implementation fidelity framework. …”

Incubation of <i>T</i>. <i>brucei</i> with Pol I transcription inhibitors results in a dramatic decrease in VEX1 foci. by Louise E. Kerry (3815164)

DataSheet_1_A point mutation in MC06g1112 encoding FLOWERING LOCUS T decreases the first flower node in bitter gourd (Momordica charantia L.).docx by Jian Zhong (329110)

“…A point mutation (C277T) in MC06g1112, which results in a P93S amino acid mutation between parental lines, may be responsible for decreasing FFN in bitter gourd. …”

Diagram of study design and observation points for comparison study. by Sheila K. West (7245476)

Structural details for each point mutation studied by X-ray crystallography in this study. by Aleksi Sutinen (10039145)

Models of G48D, M78I, G125C, and A146V RAD52 point mutants. by Abdulaziz B. Hamid (13804692)

A Point Mutation in p190A RhoGAP Affects Ciliogenesis and Leads to Glomerulocystic Kidney Defects by Katherine Stewart (848894)

Decreased neutrophil and monocyte antigen expression in the paws of anti-S100A9-treated mice. by Annabelle Cesaro (112070)

Loss of cytoplasmic incompatibility in <i>Wolbachia</i>-infected <i>Aedes aegypti</i> under field conditions by Perran A. Ross (844275)

“…To investigate the critical temperature range for the loss of <i>Wolbachia</i> infections, we held <i>Ae</i>. <i>aegypti</i> eggs in thermocyclers for one week at a range of cyclical temperatures. …”