(A) HepG2-hNTCP were exposed to DMSO or different concentrations of Bexarotene (1 μM, 10 μM, and 20 μM) for 72 h; cell viability was then evaluated by XTT assay. by Sameh A. Gad (12269979)

S1 Dataset - by Nelmo Jordão Manjate (16324619)

Subjects:

Estimated mean values for light interception. by Torsten Schober (20485754)

“…However, with increasing PD, the proportion of higher-concentrated inflorescence fractions from upper canopy layers increased from 46% to 68%, while an extension of DVP shifted this proportion only marginally from 45% to 50%. In the context of standardized production, we therefore advocate high-density production systems that increase the proportion of desired inflorescence fractions from upper canopy layers.…”

Total, free, and bound thrombin of 10,000 simulations of blood clotting over collagen/ TF under venous flow rate. by Jason Chen (15937)

Subjects:

Baseline clinical profile of hospitalized COVID-19 patients with low and high renalase. by Basmah Safdar (12213257)

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

Fibrin concentration of 10,000 simulations compared to experimental data of blood clotting over collagen/ TF under venous flow rate. by Jason Chen (15937)

Subjects:

One-way sensitivity analysis, <i>Immediate ART</i> strategy compared to <i>ART<350/μL</i>. by Eric N. Ouattara (6890174)

FTY720 decreased viability, proliferation, and motility and induced apoptosis in human hepatoblastoma cells. by Laura L. Stafman (6577184)

“…<p>(A) Following 24 hours of treatment with FTY720, the viability of HuH6 cells measured using the alamarBlue cell viability assay was significantly decreased (LD₅₀ = 8.4 μM, p ≤ 0.05). (B) Following 24 hours of treatment with FTY720, the proliferation of HuH6 cells measured using the CellTiter 96 cell proliferation assay was significantly decreased (IC₅₀ = 6.4 μM, p ≤ 0.05). …”

Oral administration of TVSE decreases angiogenesis in 4T1 tumors in BALB/c mice. by Hyun Sook Lee (8039876)

Umbelliprenin treatment decreased the expression of MMP2 and MMP9 in gastric cancer cells. by Lijing Zhang (463702)

Reduction of OPL and decreased number of horizontal cells in P18 Oc-deficient mice. by Michaela Kreplova (9239560)

Fig 10 - by Vu Phong Lam (19225959)

Subjects:

rHSP60 decreases viability of B lymphocyte cell line but not macrophage one. by Igor Emiliano L. Souza (18196495)

Decreased ISCs and increased goblet cells after intestinal specific loss of MLL1. by Neha Goveas (11790822)

“…(B) Percent of weight loss of <i>Mll1</i>^{<i>FC/+; Vil-Cre-ERT2/+</i>} (n = 6) and of <i>Mll1</i>^{<i>FC/FC; Vil-Cre-ERT2/+</i>} (n = 10) mice. Mean ± s.d. is shown (p = 0.007, Student’s <i>t</i>-test). …”

Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(F)</b> qPCR analysis for cholesterogenic genes from NIH3T3 cells exposed to cholesterol (50 μm) or 25-hydroxycholesterol (10 μm) under 5% or 1% CO₂ for 4 h (mean ± SE, <i>n</i> = 3 biological replicates per condition, ***<i>P</i> < 0.001, nonsignificant (ns), two-way ANOVA with Bonferroni’s multiple comparisons test). …”

Cinacalcet administered early in the inactive phase markedly decrease parathyroid Ki-67 index. by Søren Egstrand (10906087)

“…(B) For each group, the median Ki-67 immunostained parathyroid sample closest to the group mean is shown. Each dot represents one sample. Scale bars measures 50μm.…”

Loss of Prox1a decreases PR production at 120 hours post-ablation. by Kellie Veen (17343374)

Increased osteoblastic activity and decreased osteoclastogenesis in TgLRAP cells <i>in vitro</i>. by Naoto Haruyama (487384)

“…Bars = 500 μm. The experiments were repeated 3 times. Each column represents the mean ± SD. …”