Showing 41 - 60 results of 15,464 for search '(( 50 ((((ng decrease) OR (we decrease))) OR (nn decrease)) ) OR ( 10 nm decrease ))', query time: 0.52s Refine Results
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    The NG50 of ccTSA on datasets from 4 organisms with different sequence coverage and k-mer values. by Jung Ho Ahn (157844)

    Published 2012
    “…The k-mer values were varied from 19 to 35 on 36 bp data and from 37 to 73 on 76 bp data. In most datasets, NG50 values increased then decreased as we increased the k-mer values. …”
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    GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) by F. Anthony Romero (2452198)

    Published 2017
    “…Structure–activity relationship studies coupled with further structure-based design targeting the LPF shelf, BC loop, and KAc regions allowed us to significantly increase potency and selectivity, resulting in the identification of non-CNS penetrant <b>19</b> (GNE-781, TR-FRET IC<sub>50</sub> = 0.94 nM, BRET IC<sub>50</sub> = 6.2 nM; BRD4(1) IC<sub>50</sub> = 5100 nΜ) that maintained good in vivo PK properties in multiple species. …”
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    Robust Operation of Mesoporous Antireflective Coatings under Variable Ambient Conditions by Barry Reid (1559488)

    Published 2018
    “…For high-surface-energy materials, pores on the 2–50 nm (i.e., on the subwavelength scale) are subject to capillary condensation by surrounding gas phase water molecules, which hampers their functioning. …”