First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

Subjects:

Does Mean Platelet Volume Decrease in the presence of Coronary Artery Fistula? by Isa Sincer (7234577)

“…Conclusion: The present study suggests that MPV may decrease in patients with CAF.</p></div>…”

Decreased protection of NMT in <i>ACBD6</i>-deficient cells. by Eric Soupene (64584)

Effect of melatonin (50 μM) on the TGF-β1 (10 ng/mL, 72 h)-mediated TGF-β1/Smad pathway and EMT in HBdSMCs. by Yang Zhang (30734)

IODVA1 inhibits lamellipodia and circular dorsal ruffle (CDR) formation in MDA-MB-231 cells and decreases Rac activation. by Anjelika Gasilina (8566296)

Low oscillatory shar stress <i>Arf6</i> heterozygosity decreases Arf6 expression. by Venkateswara R. Gogulamudi (15447428)

Image_1_Decrease in Serum Urate Level Is Associated With Loss of Visceral Fat in Male Gout Patients.tif by Zijing Ran (11429935)

“…Objective<p>To clarify the relationship between serum urate (SU) decrease and visceral fat area (VFA) reduction in patients with gout.…”

All-cause gastroenteritis hospitalisations of children decreased after the introduction of rotavirus vaccine in Stockholm by Selma Olsson-Åkefeldt (11500789)

IFN-g decrease cell viability of Hepa1-6 cells. by Hitomi Morihara (18607200)

Table_1_Decreased Serum Brain-Derived Neurotrophic Factor Concentrations 72 Hours Following Marathon Running.DOCX by Astrid Roeh (11136600)

“…<p>Background: Physical exercise has been linked to beneficial effects on brain plasticity. One potential key mechanism for this relationship is an exercise-induced increase of brain-derived neurotrophic factor (BDNF). …”

DataSheet_1_Decrease in Serum Urate Level Is Associated With Loss of Visceral Fat in Male Gout Patients.docx by Zijing Ran (11429935)

“…Objective<p>To clarify the relationship between serum urate (SU) decrease and visceral fat area (VFA) reduction in patients with gout.…”

Image_3_A Shift in Myeloid Cell Phenotype via Down Regulation of Siglec-1 in Island Macrophages of Bone Marrow Is Associated With Decreased Late Erythroblasts Seen in Anemia of Cri... by Shirin Hasan (7894118)

“…There were more (2.5-fold) EEBs and less LEBs (2.4-fold) per million TBM cells in B; with a corresponding decrease in Siglec-1 and Ly6G expressions in EBIMØ associated with EEB. …”

Image_4_A Shift in Myeloid Cell Phenotype via Down Regulation of Siglec-1 in Island Macrophages of Bone Marrow Is Associated With Decreased Late Erythroblasts Seen in Anemia of Cri... by Shirin Hasan (7894118)

“…There were more (2.5-fold) EEBs and less LEBs (2.4-fold) per million TBM cells in B; with a corresponding decrease in Siglec-1 and Ly6G expressions in EBIMØ associated with EEB. …”

Global Land Use Change Impacts on Soil Nitrogen Availability and Environmental Losses by Jing Wang (6206297)

“…By compiling a global data set of 1,782 paired observations from 185 publications, we show that land use conversion from natural to managed ecosystems significantly reduced NNM by 7.5% (−11.5, −2.8%) and increased NN by 150% (86, 194%), indicating decreasing N availability while increasing potential N loss through denitrification and nitrate leaching. …”

Detailed meta–analyses in untreated hypothyroid patients compared with controls for each HRV parameters: RR intervals, SDNN, RMSSD, pNN50, TP, LF, HF, LF/HF. by Valentin Brusseau (12769704)

Decreased membrane localization of myrGFP in <i>ACBD6</i>-deficient cells. by Eric Soupene (64584)

ROC curve and P-R curve (attack traffic proportion = 50%). by Longyan Ran (18452261)

SLAMF6 knock down or knock out leads to a decrease in TCR activation. by Matthew A. Dragovich (6843362)

Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3‑Oxo-3,4-dihydro‑2<i>H</i>‑ben... by Shuhei Ikeda (2380180)

“…Starting from hit compound <b>1</b> and its co-crystal structure with MAGL, structure-based drug discovery (SBDD) approach enabled us to generate various spiro scaffolds like <b>2a</b> (azetidine-lactam), <b>2b</b> (cyclobutane-lactam), and <b>2d</b> (cyclobutane-carbamate) as novel bioisosteres of 3-oxo-3,4-dihydro-2<i>H</i>-benzo­[<i>b</i>]­[1,4]­oxazin-6-yl moiety in <b>1</b> with higher lipophilic ligand efficiency (LLE). …”

DataSheet_1_Decreased TCF1 and BCL11B expression predicts poor prognosis for patients with chronic lymphocytic leukemia.docx by Taotao Liang (9944552)

“…Then the expression and prognostic values of TCF1 and its partner gene B cell leukemia/lymphoma 11B (BCL11B) were explored for 505 CLL patients from 6 datasets and validated with 50 CLL patients from Henan cancer hospital (HNCH). …”