VCP inhibition induces accumulation of ubiquitinated-proteins and decreases NFκB-expression. by Kyla Walworth (3150936)

“…The increase in ubiquitinated-protein accumulation in soluble protein-fraction suggests that the DDN^DBeQ treatment alters VCP-function resulting in proteostasis-inhibition and ER-accumulation of these proteins. We also see a significant decrease in expression of tumor-mediator, NFκB in DDN/DDN^DBeQ treated samples as compared to the control-vehicle, although DDN^DBeQ was most effective as anticipated. …”

Luteolin decreases production of IL-6, IL-8 and VEGF in TNF-triggered primary NHEKs. by Zuyi Weng (109988)

Extent of demyelination is decreased following NgR knock down. by Fereshteh Pourabdolhossein (624998)

Hepatic Expression of Detoxification Enzymes Is Decreased in Human Obstructive Cholestasis Due to Gallstone Biliary Obstruction by Jin Chai (183630)

“…</p><p>Results</p><p>The levels of bile acid synthetic enzymes, CYP7B1 and CYP8B1, and the detoxification enzyme CYP2B6 were increased in cholestatic livers by 2.4-fold, 2.8-fold, and 1.9-fold, respectively (<i>p</i><0.05). …”

Decreased B cell proliferation upon MPA and 6-MP stimulation. by Anouk von Borstel (7421039)

Association of polymorphic IC_50s versus wild<i>-</i>type at codon 876 in selected drugs tested. by Winnie Okore (14139712)

Subjects:

IL-1Ra expressed by MSCs decreased Th17 differentiation. by Kijun Lee (4888660)

CXCL8 (2, 20, and 200 pg/ml) and CCL20 (5, 50, and 500 pg/ml) enhanced Ki-67 gene expression, but only 200 pg/ml of CXCL8 and 500 pg/ml of CCL20 enhanced early osteogenic marker ge... by Janak L. Pathak (759122)

miR-105 results in decreased Cdk6 expression at both the mRNA and protein levels. by D. Rice Honeywell (442714)

“…<p>(A–B) PC3 cells were transfected with 50 nM miR-105 or control mimics as described in materials and methods and relative levels of Cdk6 expression were assessed over time. …”

Knockdown of NG2 by siRNA results in decreased viability and a reduction in PARP levels. by Frank Maus (792209)

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

Subjects:

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

Subjects:

Decrease of 4 Asp isomers at 70°C. by Kenzo Aki (386666)

“…<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0058515#pone-0058515-g007" target="_blank">Figure 7b:</a> decrease of L-β-Asp with incubation of T6-Lβ peptide at 70°C. …”

Circulating APRIL levels are decreased in diabetic patients. by Adriana Carvalho-Santos (814114)

Decrease in activity of transcriptional factor NRF2 in MCF-7 cells exposed to gDNA^OX at final concentrations of 50 ng/mL for 2 hours. by Svetlana V. Kostyuk (473354)

HemaMax administration decreased leukopenia (a) and thrombocytopenia (b) at nadir in irradiated, unsupported rhesus monkeys. by Lena A. Basile (331369)

Decrease in vRNA in brain during antiretroviral therapy. by Sonny R. Elizaldi (9684796)

A decrease in CD44+ cells in response to hypoxia. by Daniel V. Brown (3797809)

Sulforaphane decreases IL-6, TNF-α, IL-17, and total IgG levels. by Su-Jin Moon (424173)

Correlation between axolysis and mitochondrial swelling or axolysis and a decreased NNND, respectively. by Johanna Prinz (836737)