Hemoglobin A1c Levels and Risk of Severe Hypoglycemia in Children and Young Adults with Type 1 Diabetes from Germany and Austria: A Trend Analysis in a Cohort of 37,539 Patients be... by Beate Karges (640991)

“…Based on advances in diabetes technology and pharmacotherapy, we hypothesized that the inverse association between severe hypoglycemia and HbA1c has decreased in recent years.…”

Meta-analysis of angina pectoris attack time. by Xiaoqi Wu (9503481)

Evolution of the index lesion over time during the study. by Oussama Mouri (573438)

“…By day 28, the mean index lesion size reduced by approximately 50% and 99% by day 100 compared with the baseline lesion.…”

Fig 4 - by Nehal Shawky Nagy (17721213)

“…The Rotenone group shows multiple positive α—synuclein neurons (arrows), while the gonadal extract-treated rotenone group shows decreased expression. (IHC, x400, scale bar 50 microns). …”

Baseline Transmission (None) and Five Intervention Scenarios: Q, QI, QA, QIA, and QIAC by Joseph T Wu (31525)

“…Therefore, the rate of transmission decreased by 75% within a peer group when one of two infected individuals complied with quarantine and by 96% if both did. …”

DataSheet_1_GMP-Compliant Manufacturing of TRUCKs: CAR T Cells targeting GD2 and Releasing Inducible IL-18.pdf by Wolfgang Glienke (12283652)

“…Based on our previous development and validation of automated and closed processing for GMP-compliant manufacturing of CAR T cells, we here present the proof of feasibility for translation of this method to TRUCKs. …”

Changes in Renal Function and Oxidative Status Associated with the Hypotensive Effects of Oleanolic Acid and Related Synthetic Derivatives in Experimental Animals by Hlengiwe Pretty Madlala (750105)

“…We also used experimental models of hypertension to further explore the effects of sub-chronic oral OA treatment and evaluated influences on oxidative status.…”

Quantitative Real-Time Polymerase Chain Reaction Measurement of <i>HLA-DRA</i> Gene Expression in Whole Blood Is Highly Reproducible and Shows Changes That Reflect Dynamic Shifts i... by Sara Cajander (2657173)

“…</p><p>Methods and Findings</p><p>Blood samples were collected from 60 patients with bacteraemic sepsis on up to five occasions during Days 1–28 after hospital admission. We found the reproducibility of the qRT-PCR method to be high by demonstrating low threshold variations (<0.11 standard deviation (SD)) of the qRT-PCR system, low intra-assay variation of Ct-values within triplicates (≤0.15 SD) and low inter-assay variations (12%) of the calculated target gene ratios. …”

Direct maintenance of acinar cell activity in lacrimal glands (LGs) by orally administrated royal jelly. by Sachiko Inoue (3621764)

“…<p>A: Effects of RJ on decreased tear secretion after postganglionic denervation (PGD; six mice). …”

Sensitivity of the long-term reduction in microfilarial load in individuals under 20 years of age to the assumed rate of decay of vaccine efficacy. by Hugo C. Turner (407442)

“…<p>The mean duration of vaccine prophylactic (against incoming L3 larvae) and therapeutic (against microfilariae) activity is 1/the rate of decay (i.e. 5, 10, 20 and 50 years). …”

Data_Sheet_1_The Role of Transthoracic Echocardiography in the Evaluation of Patients With Ischemic Stroke.pdf by Robson Sarmento Teodoro (11340303)

Over-expression of SOCS1 blocked IFN-α and IFN-λ signaling pathway. by Bing Liu (70818)

“…<p>Over-expression of SOCS1 repressed IFN-induced ISRE-luciferase activity (A), decreased IFN-α and IFN-λ induced ISG15 and MxA (B) mRNA and protein levels (C) and STAT1 phosphorylation (C) in Con1b replicon cell. …”

Fig 3 - by Nehal Shawky Nagy (17721213)

“…The Rotenone group shows multiple positive α—synuclein neurons (arrows) and the gonadal extract-treated rotenone group shows decreased expression. (IHC, x400, scale bar 50 microns). …”

Membrane depolarization and death induced by HAMLET in mitochondria and pneumococci. by Anders P. Hakansson (311436)

“…Treatment of the cells with HAMLET resulted in dissipation of both the bacterial and mitochondrial membrane potential in tumor cells seen by an increased staining with DiBAC₄(3) and a decreased staining with TMRE, respectively. <i>B</i>) Membrane potential and <i>C</i>) membrane rupture measurements in <i>S. pneumoniae</i> AL2 (D39 <b>Δ</b><i>lytA</i>), or in isolated rat liver mitochondria. …”

<i>Drosophila</i> model of diabetic cardiomyopathy. by Jianbo Na (12352)

“…Mean ± SE are shown; n = 50 total flies in two separate experiments. …”

Global Consumption Trend of Antifungal Agents in Humans From 2008 to 2018: Data From 65 Middle- and High-Income Countries by Pathadka, Swathi

“…Results: Consumption of systemic antifungal agents increased from 0.50 (in 2008) to 0.92 defined daily dose (DDD)/1000 inhabitants/day (in 2018), with a compound annual growth rate of 6.2%. …”
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Data TPP. by Zufan Alamrie Asmare (16474982)

“…</p><p>Results</p><p>In this study, the proportion of poor TPP was found to be 50.16% (95%CI = 46.23, 54.08). In the multi-variable multi-level logistic regression; having no formal education (AOR = 2.95; 95%CI: 1.41,6.15) and primary education (AOR = 2.33; 95%CI:1.04, 5.24), being a farmer (AOR = 3.02; 95%CI:1.73,5.28), and merchant (AOR = 2.63; 95%CI:1.20, 5.75), time taken to water point >30 minutes (AOR = 4.60,95CI:1.30,16.26) and didn’t receive health education about trachoma (AOR = 2.36;95CI:1.16,4.79) were significantly associated with poor TPP.…”

Data_Sheet_1_Insights Into Manganese Solubilizing Bacillus spp. for Improving Plant Growth and Manganese Uptake in Maize.docx by Ayesha Ijaz (11634421)

“…Mn deficiency is widespread mainly in dry, calcareous, and sandy soil, which leads to a significant decrease in crop yield. Mn-reducing bacteria promote the solubilization of Mn minerals, thus increasing Mn availability in soil. …”

Overproduction of C–R cells and enhanced Reelin signaling in the Nde1Lis1 cortex by Ashley S. Pawlisz (52227)

“…Compared to wild-type and Nde1Lis1 mutant, a significant decrease in the Dab1 protein level was detected in the Nde1Lis1cortex, suggesting that the overproduced Reelin in the mutant were active and could elicited Dab1 degradation.…”

Reference ranges for serum insulin-like growth factor I (IGF-I) in healthy Chinese adults by Huijuan Zhu (668017)

“…Both sexes were divided into 13 groups according to age (18, 19, 20–24, 25–29, 30–34, 35–39, 40–44, 45–49, 50–54, 55–59, 60–64, 65–69 and ≥70 years). The serum IGF-I levels were measured by performing a chemiluminescent assay (Immulite 2000®), and the LMS (Lambda-Mu-Sigma) method was applied to construct smooth centile curves of age-specific IGF-I levels.…”