DataSheet_1_ENSO coupling to the equatorial Atlantic: Analysis with an extended improved recharge oscillator model.pdf by Rodrigo Crespo-Miguel (14422728)

“…Moreover, the damping time of the ENSO fluctuations has doubled from 10 to 20 months, and the oscillation period of ENSO has decreased from 60-70 months before the 1960s to 50 months afterward. …”

Pharmacometabolomics of Response to Sertraline and to Placebo in Major Depressive Disorder – Possible Role for Methoxyindole Pathway by Hongjie Zhu (152174)

“…Patients showing a good response to sertraline had higher pretreatment levels of 5-methoxytryptamine (5-MTPM), greater reduction in 5-MTPM levels after treatment, an increase in 5-Methoxytryptophol (5-MTPOL) and Melatonin (MEL) levels, and decreases in the (KYN)/MEL and 3-Hydroxykynurenine (3-OHKY)/MEL ratios post-treatment compared to pretreatment. …”

Table_1_Contrasting Effects of Chronic Anthropogenic Disturbance on Activity and Species Richness of Insectivorous Bats in Neotropical Dry Forest.xlsx by Katarina Meramo (12099026)

“…Bats are a species-rich and functionally diverse group, with important roles in ecosystems, and are therefore recognized as a good model group for assessing the impact of environmental change. …”

Gene Co-Expression Modules as Clinically Relevant Hallmarks of Breast Cancer Diversity by Denise M. Wolf (272435)

“…As expected, the proliferation module was highly associated with decreased recurrence-free survival (RFS). Interestingly, the immune modules appeared associated with RFS even after adjustment for receptor subtype and proliferation; and in a multivariate analysis, the combination of Tcell/Bcell immune module down-regulation and proliferation module upregulation strongly associated with decreased RFS. …”

Potent Suppression of Kv1.3 Potassium Channel and IL-2 Secretion by Diphenyl Phosphine Oxide-1 in Human T Cells by Ning Zhao (84707)

“…In this study, DPO-1 blocked Kv1.3 current in a voltage-dependent and concentration-dependent manner, with IC₅₀ values of 2.58 µM in Jurkat cells and 3.11 µM in human peripheral blood T cells. …”

Hematopoietic parameters, splenomegaly and EMH of AnkT9-treated <i>Hbb^th3/+</i>- are comparable to those of WT-chimeras. by Laura Breda (328422)

“…In mice treated with T9W, and even more so in AnkT9W-treated chimeras, the amount of red pulp was decreased considerably, accounting for only about 40% to 50% of the cross-sectional area, and denoting a considerable reduction of EMH.…”

DataSheet_1_Nutrient deficiency effects on root architecture and root-to-shoot ratio in arable crops.docx by Gina Lopez (14325873)

“…However, the respective trait responses are complex, particularly at the field scale, and poorly understood due to difficulties in root phenotyping monitoring, inaccurate sampling, and environmental conditions. Here, we conducted a systematic review and meta-analysis of 50 field studies to identify the effects of nitrogen (N), phosphorous (P), or potassium (K) deficiencies on the root systems of common crops. …”

Cathelicidin Insufficiency in Patients with Fatal Leptospirosis by Janet C. Lindow (150690)

“…While drawn from a limited study size, significant conclusions include that poor clinical outcomes are associated with high systemic bacterial loads, and a decreased antibody response. …”

DataSheet1_The effect of 1-deoxynojirimycin isolated from logging residue of Bagassa guianensis on an in vitro cancer model.pdf by Susanne Suely Santos da Fonseca (18336321)

“…</p><p>Results: Assessing cell viability after 72 h (about 3 days) of treatment reveals a remarkable reduction, particularly in glioblastoma cells (A172), exhibiting a lower IC50 compared to ACP02 and MRC5 (fibroblast derived from normal lung tissue) cell lines. …”

Predicted Fur binding sequences within the promoter regions of <i>N. gonorrhoeae</i> iron-induced genes.¹ by Chunxiao Yu (561760)

“…1<p>Iron regulation as previously determined by microarray analyses of <i>N. gonorrhoeae</i> grown in defined medium CDM (-Fe) or CDM with 10 µM ferric nitrate (+Fe) <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0096832#pone.0096832-Ducey1" target="_blank">[50]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0096832#pone.0096832-Jackson1" target="_blank">[51]</a>.…”

Early RPMs increase the range without increasing the average speed of chromosome movement. by Chih-Ying Lee (162089)

“…By this measure, RPMs in <i>mps3-dCC</i> are not significantly different from wild-type at t₃ (*) while RPMs are significantly decreased in <i>mps3-dAR</i> and <i>csm4Δ</i>. Statistical analysis is in the legend to <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002730#pgen-1002730-t001" target="_blank">Table 1</a>. …”

Do Spatially-Implicit Estimates of Neutral Migration Comply with Seed Dispersal Data in Tropical Forests? by François Munoz (447828)

“…Most estimates of <i>I</i> were derived from large plots (10–50 ha) and were too large to be accounted for by a Cauchy kernel. …”

Stem-binding bnAbs prevent membrane fusion in an <i>in vitro</i> single particle fusion assay. by Boerries Brandenburg (32421)

“…Upon lowering the pH from 7.4 to 5.0 (t = 0 seconds), viruses incubated with only 15 nM CR8020 or CR6261 undergo HA-mediated fusion with the target membrane, visualized as a rapid increase in signal due to fluorescence dequenching followed by diffusion of R18 molecules away from the fusion site (<b>B</b> and <b>C</b>, yellow triangles), whereas no fusion events occur when viruses are incubated with 1500 nM bnAbs (<b>D</b> and <b>E</b>). …”

Supporting Information. by Segni B. Ligaba (695899)

“…D, Network analysis of genes (highlighted in blue) whose knockdown decreased HFK growth. Fig. E, Uncropped and unadjusted western blots shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0116755#pone.0116755.g004" target="_blank">Fig. 4C</a>. …”

Table_1_Subclinical Hyperthyroidism Could Predict Poor Outcomes in Patients With Acute Ischemic Stroke Treated With Reperfusion Therapy.DOCX by Sang-Hwa Lee (6092549)

“…However, compared with patients in the euthyroid state, patients with subclinical hyperthyroidism had an increased risk of poor functional outcomes at 3 months after a stroke (adjusted odds ratio [OR] 2.50, 95% confidence interval [CI] 1.01–6.14 for a mRS score of 3 to 6) and a decreased rate of successful reperfusion after reperfusion therapy (OR 0.13, 95% CI 0.04–0.43).…”

Expression of Ring1B is influenced by the 5′ UTR. by Erwin Boutsma (377558)

“…Numbers correspond to the constructs in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0002322#pone-0002322-g002" target="_blank">figure 2A</a>. …”

Fibroblast growth factor 9 (FGF9) inhibits myogenic differentiation of C2C12 and human muscle cells by Jian Huang (7250)

“…FGF9 (10–50 ng/mL) significantly decreased mRNA expression of <i>MyoG</i> and <i>Mhc</i> while increasing the expression of <i>Myostatin</i>. …”

An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing by Raymond W. Wong (8463498)

“…<div><p>The ability of HIV-1 to evolve resistance to combined antiretroviral therapies (cARTs) has stimulated research into alternative means of controlling this infection. We assayed >60 modulators of RNA alternative splicing (AS) to identify new inhibitors of HIV-1 RNA processing—a segment of the viral lifecycle not targeted by current drugs—and discovered compound N-[4-chloro-3-(trifluoromethyl)phenyl]-7-nitro-2,1,3-benzoxadiazol-4-amine (5342191) as a potent inhibitor of both wild-type (<i>Ba-L</i>, <i>NL4-3</i>, <i>LAI</i>, <i>IIIB</i>, and <i>N54</i>) and drug-resistant strains of HIV-1 (IC₅₀: ~700 nM) with no significant effect on cell viability at doses tested. 5342191 blocks expression of four essential HIV-1 structural and regulatory proteins (Gag, Env, Tat, and Rev) without affecting total protein synthesis of the cell. …”

Image_1_Weaning Age Affects the Development of the Ruminal Bacterial and Archaeal Community in Hu Lambs During Early Life.JPEG by Huiling Mao (6520772)

“…Compared to W30, PW30 had a decreased relative abundance of Bacteroidetes. …”

Table_1_Weaning Age Affects the Development of the Ruminal Bacterial and Archaeal Community in Hu Lambs During Early Life.DOCX by Huiling Mao (6520772)

“…Compared to W30, PW30 had a decreased relative abundance of Bacteroidetes. …”