Knock-down of <i>PYCR</i> genes effect is independent of proline and nucleotide biosynthesis. by Saif Sattar Alaqbi (12055053)

Fig 7 - by Tong Zhuang (17847113)

The working model of blood pressure regulation by Csk and Angiotensin II through Src. by Hyeon-Ju Lee (796527)

Monobenzyltin Complex C1 Induces Apoptosis in MCF-7 Breast Cancer Cells through the Intrinsic Signaling Pathway and through the Targeting of MCF-7-Derived Breast Cancer Stem Cells... by Somayeh Fani (2967933)

“…<p><b>(A, B) Aldefluor assay of MCF-7 cancer stem cells, (C) western blot analysis of protein markers of the Wnt/β-catenin self-renewal pathway in MCF-7 treated cells with a concentration of 2.5 μg/mL (IC</b>_<b>50</b><b>).…”

Image_2_The impact of genetic modified Ma bamboo on soil microbiome.pdf by Kai Wang (21246)

“…<p>Evaluating the potential alteration of microbial communities is a vital step for biosafety of genetic modified plants. Recently, we have produced genetic modified Ma bamboo with increased cold and drought tolerance by anthocyanin accumulation. …”

Characterization of the Thermally Induced Topochemical Solid-State Transformation of NH₄[N(CN)₂] into NCNC(NH₂)₂ by Means of X-ray and... by Bettina V. Lotsch (1467520)

“…The mechanism of the solid−solid transformation of NH₄[N(CN)₂] into NCNC(NH₂)₂, which represents the isolobal analogue of Wöhler's historic conversion of ammonium cyanate into urea, has been investigated by temperature-dependent single-crystal and powder X-ray diffraction, neutron powder diffraction, and Raman and solid-state NMR spectroscopy as well as thermoanalytical measurements. …”

Characterization of the Thermally Induced Topochemical Solid-State Transformation of NH₄[N(CN)₂] into NCNC(NH₂)₂ by Means of X-ray and... by Bettina V. Lotsch (1467520)

“…The mechanism of the solid−solid transformation of NH₄[N(CN)₂] into NCNC(NH₂)₂, which represents the isolobal analogue of Wöhler's historic conversion of ammonium cyanate into urea, has been investigated by temperature-dependent single-crystal and powder X-ray diffraction, neutron powder diffraction, and Raman and solid-state NMR spectroscopy as well as thermoanalytical measurements. …”

Bacterial amyloid curli acts as a carrier for DNA to elicit an autoimmune response via TLR2 and TLR9 by Sarah A. Tursi (3927317)

“…Here, we show that DNA complexed with amyloid curli powerfully stimulates Toll-like receptor 9 (TLR9) through a two-step mechanism. First, the cross beta-sheet structure of curli is bound by cell-surface Toll-like receptor 2 (TLR2), enabling internalization of the complex into endosomes. …”

IGF-1 induces an increase in <i>PRNP</i> expression through the PI3K-Akt-FOXO3a pathway. by Ting Liu (45625)

“…No notable changes were detected after 1 hour of treatment, but the <i>PRNP</i> mRNA level gradually decreased over time, and an approximately 50% decrease was observed after 24 hours of treatment. …”

Enhanced Cuprophilic Interactions in Crystalline Catalysts Facilitate the Highly Selective Electroreduction of CO₂ to CH₄ by Lei Zhang (38117)

“…Moreover, the detailed DFT calculations also prove that the cuprophilic interactions can effectively facilitate the electroreduction of CO₂ to CH₄ by decreasing the Gibbs free energy change of potential determining step (*H₂COOH → *OCH₂). …”

Table2_Non-GM Genome Editing Approaches in Crops.DOCX by Zheng Gong (419954)

“…Although efficient, these methods pose several problems, including 1) The transformation process requires laborious and time-consuming tissue culture and regeneration steps; 2) many crop species and elite varieties are recalcitrant to transformation; 3) The segregation of transgenes in vegetatively propagated or highly heterozygous crops, such as pineapple, is either difficult or impossible; and 4) The production of a genetically modified first generation can lead to public controversy and onerous government regulations. …”

Meta-analyses of the association of <i>G6PC2</i> allele variants with elevated fasting glucose and type 2 diabetes by Yuanyuan Shi (563992)

“…Per increment of G allele at rs560887 and A allele at rs573225 resulted in a FG 0.070 mmol/l and 0.075 mmol/l higher (ß (95% CI) = 0.070 (0.060, 0.079), <i>p</i> = 4.635e-50 and 0.075 (0.065, 0.085), <i>p</i> = 5.856e-48, respectively). …”

Auxiliary proteins may act as rate-limiting factors of the m6A writer complex. by Kiran Pandey (9282593)

“…<p>Here we use the term ‘rate-limiting’ to describe the functionally limiting component, based on knockdown correlations rather than direct kinetic measurements. About 50% of m6A remained when METTL3 was reduced to 5%, showing that only a small amount of METTL3 is required to maintain physiological levels of m6A in mRNA. …”

Video_2_Controlling Fibronectin Fibrillogenesis Using Visible Light.AVI by Tetyana Gudzenko (9096176)

2.tif from The three-dimensional flower-like Bi₂WO₆ assisted by ethanolamine through microwave method for efficient photocatalytic activity by Xingchen Liu (524190)

“…The three-dimensional flower-like Bi₂WO₆ was synthesized through one-step microwave method (the reaction temperature was 434 K and the reaction took 10 min), with the assist of ethanol amine. …”

Catalytic C–H Amination Mediated by Dipyrrin Cobalt Imidos by Yunjung Baek (6671804)

“…The mechanism of C–H amination was probed via kinetic isotope effect experiments [<i>k</i>_H/<i>k</i>_D = 10.2(9)] and initial rate analysis with <i>para</i>-substituted azides, suggesting a two-step radical pathway. …”

Table_1_IRE1-bZIP60 Pathway Is Required for Nicotiana attenuata Resistance to Fungal Pathogen Alternaria alternata.XLSX by Zhen Xu (92379)

A Reduce and Replace Strategy for Suppressing Vector-Borne Diseases: Insights from a Stochastic, Spatial Model by Kenichi W. Okamoto (500514)

“…We find this “reduce and replace” strategy can decrease the frequency of competent vectors below 50% two years after releases end. …”

Sampling frame and survey response. by Charity Oga-Omenka (6635432)

A Suppressive Antagonism Evidences Progesterone and Estrogen Receptor Pathway Interaction with Concomitant Regulation of <i>Hand2</i>, <i>Bmp2</i> and ERK during Early Decidualizat... by Ana C. Mestre-Citrinovitz (568049)

“…Here we describe a suppressive interaction between progesterone receptor (onapristone) and estrogen receptor (ICI182780) antagonists and their relation to a rescue phenomenon with concomitant regulation of <i>Hand2</i>, <i>Bmp2</i> and p-ERK1/2 during the early decidualization steps. …”