DataSheet_1_Multivariate Mendelian randomization provides no evidence for causal associations among both psoriasis and psoriatic arthritis, and skin cancer.pdf by Nianzhou Yu (14825545)

DataSheet2_Real-World Data and Budget Impact Analysis (BIA): Evaluation of a Targeted Next-Generation Sequencing Diagnostic Approach in Two Orthopedic Rare Diseases.PDF by Elena Pedrini (224672)

“…This study evaluated the analytical validity and the budget impact of an NGS-Ion Torrent™ approach for the molecular germline diagnosis of two musculoskeletal rare diseases.</p><p>Methods: Two cohorts of 200 and 199 patients with suspect or clinical diagnosis of multiple osteochondromas (MO) and osteogenesis imperfecta (OI) previously evaluated with a single-gene diagnostic protocol were re-analyzed using a targeted NGS assay. …”

Fig 3 - by Debarpan Dhar (724473)

Upregulation of Cx30 impairs pyramidal cell excitability and action potential properties. by Eléonore Hardy (15208385)

A Novel Splice-Site Mutation in Angiotensin I-Converting Enzyme (ACE) Gene, c.3691+1G>A (IVS25+1G>A), Causes a Dramatic Increase in Circulating ACE through Deletion of the Transmem... by Alexandre Persu (396983)

“…The levels of renin-angiotensin-aldosterone system components in the mutated cases and wild-type controls were similar, both at baseline and after 50 mg captopril. Compared with non-affected members, quantification of ACE surface expression and shedding using flow cytometry assay of dendritic cells derived from peripheral blood monocytes of affected members, demonstrated a 50% decrease and 3-fold increase, respectively. …”

DataSheet2_Transcriptional Repression and Protein Degradation of the Ca2+-Activated K+ Channel KCa1.1 by Androgen Receptor Inhibition in Human Breast Cancer Cells.PDF by Anowara Khatun (5104091)

“…A treatment with the antiandrogen bicalutamide or enzalutamide for 48 h significantly suppressed (1) depolarization responses induced by paxilline (PAX), a specific K_Ca1.1 blocker and (2) PAX-sensitive outward currents induced by the depolarizing voltage step. …”

A- and D‑Ring Structural Modifications of an Androsterone Derivative Inhibiting 17β-Hydroxysteroid Dehydrogenase Type 3: Chemical Synthesis and Structure–Activity Relationships... by Francisco Cortés-Benítez (4523380)

“…Decreasing the intratumoral androgen biosynthesis by using an inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) is a strategy to treat prostate cancer. …”

A custom built widefield microscope. by Dinu F. Albeanu (58044)

“…The ordering of parts is as follows: CCD camera, an F to C mount adapter with an emission filter placed inside or on top of the coupler, a 62 mm, 105 mm FL lens, a 62 mm to 52 mm step down ring, a 52 mm to 52 mm coupling ring, and a 52 mm, 50 mm FL lens. …”

Demographic characteristics of the survey sample. by Stephanie Niño de Rivera (19501049)

“…Overall, 50% of the sample identified as women, 13% as Black or African American, and 7% as Hispanic or Latino, with a mean age of 46 years. …”

Image_1_Axial spondyloarthritis patients have altered mucosal IgA response to oral and fecal microbiota.tiff by Tejpal Gill (618904)

Image_2_Axial spondyloarthritis patients have altered mucosal IgA response to oral and fecal microbiota.tiff by Tejpal Gill (618904)

The average performance of two-sample testing approaches with smaller non-faller population. by Ioannis Bargiotas (3390458)

“…<p>The non-fallers were progressively excluded, by a step of 10%, in order to balance the size of the two groups without excluding fallers. …”

Minocycline administration ameliorates photoreceptor cell death in <i>Mertk</i>^−/−<i>Cx3cr1</i>^<i>GFP/+</i><i>Ccr2</i>^<i>RFP/+</i> mice. by Ryo Terauchi (10687481)

Capacity of the insect AST-A peptides to activate the <i>A</i>. <i>coluzzii</i> GPRALS. by Rute C. Felix (5664397)

Reducing AHP duration in mice with upregulated astroglial Cx30 restores pyramidal cell excitability and excitatory synaptic transmission. by Eléonore Hardy (15208385)

Table_2_Social Media and Large Carnivores: Sharing Biased News on Attacks on Humans.xlsx by Veronica Nanni (8613942)

Presentation_1_Low-Dose Mycophenolate Mofetil for Treatment of Neuromyelitis Optica Spectrum Disorders: A Prospective Multicenter Study in South China.PPTX by Qiao Huang (4386955)

“…The serum AQP4-IgG titer decreased in 50 cases (63%). The median Simple McGill pain score (SF-MPQ) was reduced in 65 patients (88%) with myelitis from 17 (range 0–35) to 11 (range 0–34) after treatment (P < 0.0001). …”

A vaginal drug delivery model by Mohd. Aamir Mirza (2561590)

“…Stearic acid and Compritol 888 (1:1, w/w ratio) as lipid, a mixture of 3% Poloxomer 188 and 0.5% sodium taurocholate as surfactant and organic to aqueous ratio of 10:50 was taken. …”

Mutant S gene segment plasmid design. by Debarpan Dhar (724473)

“…The S1 UTRs, while not sufficient, were necessary for efficient packaging, as mutations of the 5′ or 3′ UTRs led to a complete loss of virus recovery. Using a second novel assay, we determined that 50 5′ nts and 50 3′ nts of S1 are sufficient to package a non-viral gene segment into MRV. …”

A Mouse Model for Studying the Clearance of Hepatitis B Virus In Vivo Using a Luciferase Reporter by Sheng-qiang Liang (359591)