Data Sheet 4_Time-updated patterns of hemoglobin and hematocrit and the risk of CKD progression.docx by Li-zhe Fu (14825593)

“…A multivariate time-dependent Cox model revealed mean_Hb and mean_HCT as independent protective factors for the composite outcome {hazard ratio (HR) (95% confidence interval [CI]): 0.851 (0.786, 0.921) g/L, p=0.000; 0.578% (0.441%, 0.758%), p=0.000}. …”

Data Sheet 1_Time-updated patterns of hemoglobin and hematocrit and the risk of CKD progression.docx by Li-zhe Fu (14825593)

“…A multivariate time-dependent Cox model revealed mean_Hb and mean_HCT as independent protective factors for the composite outcome {hazard ratio (HR) (95% confidence interval [CI]): 0.851 (0.786, 0.921) g/L, p=0.000; 0.578% (0.441%, 0.758%), p=0.000}. …”

Organ level model. by Shayoni Ray (179927)

“…<p>An organ-level simulation containing three ideally localized clefts is shown at (a) 0 MCS and (b) 1500 MCS (Scale = 50 µm). The results were quantified with (c) cleft depth and (d) spanning angle. …”

Oxidative stress in INS1E and alphaTC1 cells in 3D aggregates. by Mireille M. J. P. E. Sthijns (12245491)

“…B) Seeding INS1E and alphaTC1 cells in the ratios 100:0 and 50:50 in 3D aggregates exposed to 500 μM H₂O₂ decreased the percentage of oxidative stress–positive INS1E cells. …”

Epigenome-wide association studies of occupational exposure to benzene and formaldehyde by Rachael V. Phillips (6880574)

“…In the benzene EWAS, we found genome-wide significant alterations, i.e., FWER-controlled <i>P</i>-values <0.05, in the mean and variance of methylation at 22 and 318 CpG sites, respectively, and in mean methylation of a large genomic region. …”

Table_1_Favorable Effects of Tacrolimus Monotherapy on Myasthenia Gravis Patients.DOCX by Zhirong Fan (9566711)

“…QMG scores significantly decreased at 6 and 12 months, with mean differences and 95% CIs of −4.67(−6.88, −2.45) and −5.77 (−7.55, −4.00), respectively. …”

Cytotoxicity of candidate agents to cholangiocarcinoma cells. by Chiara Braconi (235041)

“…All three compounds decreased cell viability in a concentration-dependent manner, with an IC50 for felodipine of 26±5 µM, nitrendipine, 44±10 µM and nifedipine, 15±4 µM. …”

Effect of Ang II and Zol on EPC <i>in vitro</i> tube formation ability. by Jin-Xiu Yang (128753)

“…B: Light micrographs showing typical tubules (200×). <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046511#s3" target="_blank">Results</a> are the mean ± SD, n = 5. …”

DREAM expression in human placenta of first, second and third trimester. by Dora Baczyk (105789)

“…DREAM is stained green and nuclei are stained blue (DAPI). Each image is a representative of 50 fields examined (original magnification, ×400). …”

Expression of SDF-1 in the bone marrow and frequency of GFP⁺CXCR4⁺ cells in peripheral blood. by Koji Ataka (489887)

“…<p>Effects of β₃-adrenergic blockade on the infiltration of bone marrow-derived microglia in the PVN. (A) Chronic PS decreased the SDF-1 concentration in the bone marrow (<i>n</i> = 3−4) and increased the frequency of CXCR4⁺ monocytes in the peripheral blood (<i>n</i> = 4−6). …”

Aptamer L44 binds predominantly to TESA and protein extracts from <i>T. cruzi</i> trypomastigotes. by Rana Nagarkatti (90297)

“…<p>100-L44 was used to perform an ELA assay in a polystyrene 96 well plate coated with 50 µl/well of decreasing amounts, beginning at a concentration of 100 ng/µl, of TESA and trypomastigote extracts (Trypo) from <i>T. cruzi</i> Tulahuen strain, and epimastigote extracts (Epi) from <i>T. cruzi</i> Y2 strain. …”

SB-216763 inhibits the GSK-3 pathway. by Pramod K. Dash (246530)

“…<p><b>A</b>) Representative images of western blots for phospho-GSK-3ß, phospho-LRP6, phospho-ß-Catenin, phospho-Akt, and phospho-ERK in response to i.p. injection of SB-216763 (2.5 and 5.0 mg/kg) or vehicle (0 mg/kg) (n = 3/group). …”

Effects of metformin on angiogenic activities and apoptosis of hRVECs. by Jing Han (43038)

“…<p><b>(A)</b> Proliferation assay showed that metformin treatment at 5–50mM for 24 hours reduced hRVEC proliferation dose-dependently. …”

9.2.27PE in combination with ABT-737 induces apoptosis in melanoma cells. by Karianne Risberg (207221)

“…To determine whether caspases and cathepsins were involved in the decreased cell viability caused by the combination of 9.2.27PE and ABT-737, the cells were pre-treated with for 1 h with Z-VAD-FMK (50 µM)±Z-FA-FMK (50 µM). …”

Cerebellar cortex of SCA3 patients. by Tzu-Yun Wang (427574)

Cerebral cortex of SCA3 patients. by Tzu-Yun Wang (427574)

The pool of premyelinating OL lineage cells is significantly increased following rHI; PreOLs are less susceptible to acute degeneration following rHI than following late HI. by Matthew W. Hagen (627944)

“…(D) Stereology further shows a decreased rate of preOL death following rHI relative to late HI (Kruskal-Wallis: H = 7.5, p = 0.057, on 3 df; mean ± SD Control: 0.9±0.4%; Early HI: 1.2±0.9%; Late HI: 5.0±2.4%; rHI: 1.7±1.8%; Bonferroni-corrected post-hoc Mann-Whitney U-tests: *Late HI vs. …”

PAI-1 inhibition leads to the accumulation of VE-cadherin at the Golgi apparatus. by Anna E. Daniel (841267)

“…<p>(A) HUVEC were treated with PAI-039 (25 μM) or solvent (DMSO 0.1%) for four hours and stained for VE-cadherin (green) and GM130 (red) (scale bar 50 μm). …”

Training effects on brain states (example left frontal channel). by Natasha Kovacevic (5664406)

“…<p><b>(A)</b> Relaxation training effect. Left: mean participant scores with respect to the relaxation training effect, with error bars representing 95% CI. …”

DataSheet_1_Optimizing linear energy transfer distribution in intensity-modulated proton therapy using the alternating direction method of multipliers.pdf by Qingkun Fan (17379391)

“…For the prostate case, the mean LET (unit: keV/µm) at the rectum decreased from 2.65 (ICR-LET) to 2.14 (ADMM-LET).…”